Characteristics of high frequency signal propagation within a transformer winding model using transfer function analysis and experimental investigation

2005 ◽  
Author(s):  
B. Han
Keyword(s):  
Experimental Investigation ◽  
Transfer Function ◽  
High Frequency ◽  
Function Analysis ◽  
Signal Propagation ◽  
Frequency Signal ◽  
High Frequency Signal ◽  
Transfer Function Analysis ◽  
Transformer Winding

Effect of head-down-tilt bed rest and hypovolemia on dynamic regulation of heart rate and blood pressure

2000 ◽  
Vol 279 (6) ◽  
pp. R2189-R2199 ◽  
Author(s):  
Ken-Ichi Iwasaki ◽  
Rong Zhang ◽  
Julie H. Zuckerman ◽  
James A. Pawelczyk ◽  
Benjamin D. Levine
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Transfer Function ◽  
Stroke Volume ◽  
Plasma Volume ◽  
High Frequency ◽  
Function Analysis ◽  
Bed Rest ◽  
Baroreflex Control ◽  
Transfer Function Analysis

Adaptation to head-down-tilt bed rest leads to an apparent abnormality of baroreflex regulation of cardiac period. We hypothesized that this “deconditioning response” could primarily be a result of hypovolemia, rather than a unique adaptation of the autonomic nervous system to bed rest. To test this hypothesis, nine healthy subjects underwent 2 wk of −6° head-down bed rest. One year later, five of these same subjects underwent acute hypovolemia with furosemide to produce the same reductions in plasma volume observed after bed rest. We took advantage of power spectral and transfer function analysis to examine the dynamic relationship between blood pressure (BP) and R-R interval. We found that 1) there were no significant differences between these two interventions with respect to changes in numerous cardiovascular indices, including cardiac filling pressures, arterial pressure, cardiac output, or stroke volume; 2) normalized high-frequency (0.15–0.25 Hz) power of R-R interval variability decreased significantly after both conditions, consistent with similar degrees of vagal withdrawal; 3) transfer function gain (BP to R-R interval), used as an index of arterial-cardiac baroreflex sensitivity, decreased significantly to a similar extent after both conditions in the high-frequency range; the gain also decreased similarly when expressed as BP to heart rate × stroke volume, which provides an index of the ability of the baroreflex to alter BP by modifying systemic flow; and 4) however, the low-frequency (0.05–0.15 Hz) power of systolic BP variability decreased after bed rest (−22%) compared with an increase (+155%) after acute hypovolemia, suggesting a differential response for the regulation of vascular resistance (interaction, P < 0.05). The similarity of changes in the reflex control of the circulation under both conditions is consistent with the hypothesis that reductions in plasma volume may be largely responsible for the observed changes in cardiac baroreflex control after bed rest. However, changes in vasomotor function associated with these two conditions may be different and may suggest a cardiovascular remodeling after bed rest.

Spontaneous beat-by-beat fluctuations of total peripheral and cerebrovascular resistance in response to tilt

2004 ◽  
Vol 287 (3) ◽  
pp. R670-R679 ◽  
Author(s):  
Deborah D. O'Leary ◽  
J. Kevin Shoemaker ◽  
Michael R. Edwards ◽  
Richard L. Hughson
Keyword(s):  
Blood Pressure ◽  
Transfer Function ◽  
Total Peripheral Resistance ◽  
High Frequency ◽  
Function Analysis ◽  
Peripheral Resistance ◽  
Cerebrovascular Resistance ◽  
Arterial Blood ◽  
Transfer Function Analysis ◽  
Head Up Tilt

Beat-by-beat estimates of total peripheral resistance (TPR) can be obtained from continuous measurements of cardiac output by using Doppler ultrasound and noninvasive mean arterial blood pressure (MAP). We employed transfer function analysis to study the heart rate (HR) and vascular response to spontaneous changes in blood pressure from the relationships of systolic blood pressure (SBP) to HR (SBP→HR), MAP to total peripheral resistance (TPR) and cerebrovascular resistance index (CVRi) (MAP→TPR and MAP→CVRi), as well as stroke volume (SV) to TPR in nine healthy subjects in supine and 45° head-up tilt positions. The gain of the SBP→HR transfer function was reduced with tilt in both the low- (0.03–0.15 Hz) and high-frequency (0.15–0.35 Hz) regions. In contrast, MAP→TPR transfer function gain was not affected by head-up tilt, but it did increase from low- to high-frequency regions. The phase relationships between MAP→TPR were unaffected by head-up tilt, but, consistent with an autoregulatory system, changes in MAP were followed by directionally similar changes in TPR, just as observed for the MAP→CVRi. The SV→TPR had high coherence with a constant phase of 150–160°. Together, these data that showed changes in MAP preceded changes in TPR, as well as a possible link between SV and TPR, are consistent with complex interactions between the vascular component of the arterial and cardiopulmonary baroreflexes and intrinsic properties such as the myogenic response of the resistance arteries.

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