Effects of Signal Rise Time and Frequency on the Brainstem Auditory Evoked Response

1978 ◽  
Vol 21 (2) ◽  
pp. 408-416 ◽  
Author(s):  
John Cobb ◽  
Paul Skinner ◽  
John Burns
Keyword(s):  
Response Latency ◽  
Rise Time ◽  
Response Amplitude ◽  
Evoked Response ◽  
Center Frequency ◽  
Frequency Effect ◽  
Sensation Level ◽  
Auditory Evoked Response ◽  
Brainstem Auditory Evoked Response

Two experiments studied the effects of signal rise time and frequency on the brainstem auditory evoked response. In Experiment 1, five different rise times were presented, fast (10 µsec), 0.5, 1, 2.5, and 5 msec at a center frequency of 1000 Hz at three sensation levels, 20, 40, and 60 dB. As rise time was increased, response amplitude and detectability decreased and response latency increased. In Experiment 2, tonal pips were presented at 250, 500, 1000, 2000, 4000, and 8000 Hz at 40-dB sensation level. Although the effects of frequency and signal rise time were confounded, no frequency effect was apparent.

Study of brainstem auditory evoked response and biochemical markers in patients of alcohol use disorder

2021 ◽  
Vol 65 ◽  
pp. 193-200
Author(s):  
Mudassir Anis Siddiqui ◽  
Divya Srivastava ◽  
Sandeep Choudhary
Keyword(s):  
Alcohol Use ◽  
Biochemical Parameters ◽  
Alcoholic Hepatitis ◽  
Alcohol Use Disorder ◽  
Liver Enzymes ◽  
Evoked Response ◽  
Transmission Time ◽  
Control Group ◽  
Auditory Evoked Response ◽  
Brainstem Auditory Evoked Response

Objectives: Data available on brainstem auditory evoked response (BAER) and its correlation with biochemical parameters in patients of alcohol use disorder (AUD) in Indian population is scanty. Therefore, this study was undertaken to focus on the effects of AUD on BAER and liver enzymes. Materials and Methods: This case-control study included 40 males in the study group who had AUD and 40 healthy males in the control group in the age group of 20–60 years. The BAER was performed using octopus NCS/ EMG/EP (Clarity) machine. The levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase and serum bilirubin were estimated in all the subjects. Results: We observed a highly significant increase in the absolute latencies of waves III and V and interpeak latencies (IPL) I-III and I-V of BAER in the patients of AUD in this study. Significant increase in the liver enzymes and especially AST/ALT ratio of patients of AUD was seen which indicated towards subclinical alcoholic hepatitis. The latencies of waves of EPs (waves III, V, IPL I-III and IPL I-V) were positively correlated with the biochemical parameters and duration of AUD. Conclusion: Our findings indicated that AUD lead to the increase in brainstem transmission time and also lead to subclinical alcoholic hepatitis which is reflected by the increase in the liver enzymes. We concluded that chronic alcohol consumption affected the auditory pathways and delayed the auditory transmission time which was suggestive of possible demyelination of auditory tracts.

Brainstem auditory evoked response in presbyacusis

1991 ◽  
Vol 43 (1) ◽  
pp. 1-4
Author(s):  
Pawn Geol ◽  
Umesh wig ◽  
S. P. S. Yadav ◽  
Harish C. Geol ◽  
A. K. Sood
Keyword(s):  
Evoked Response ◽  
Auditory Evoked Response ◽  
Brainstem Auditory Evoked Response
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