Talker Effects on Word-Discrimination Scores of Adults With Sensorineural Hearing Impairment

1979 ◽  
Vol 44 (3) ◽  
pp. 340-349 ◽  
Author(s):  
John P. Penrod

Speech discrimination testing was completed on 30 adults with varying degrees of sensorineural hearing impairment. Tape recordings of four talkers' utterances of CID W-22 word lists served as the stimulus materials. Listeners' responses were scored independently by three experienced judges. For 26 of the 30 subjects, the difference between the lowest and highest word-discrimination score was 8% or greater. Variations in scores could not be attributed to a single talker but were spread across all talkers. A moderate negative correlation was found between each listener’s average word-discrimination score and amount of variability among his or her individual scores. The statistical analysis indicated that talker differences were responsible for only a small portion of the variability in scores and suggested that a factor of greater importance is the talker-listener interaction.

2012 ◽  
Vol 31 (7) ◽  
pp. 1267-1273 ◽  
Author(s):  
Agnieszka Pollak ◽  
Malgorzata Mueller-Malesinska ◽  
Urszula Lechowicz ◽  
Agata Skorka ◽  
Lech Korniszewski ◽  
...  

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Yen-Hui Chan ◽  
Tien-Chen Liu ◽  
Chun-Kang Liao ◽  
Yen-Fu Cheng ◽  
Ching-Hui Tsai ◽  
...  

Abstract Betel quid is one of the most widely used psychoactive substances, and is consumed by approximately 10% of the world’s population. In addition to its carcinogenicity, betel quid has also been reported to affect many organs, including the brain, heart, lungs, gastrointestinal tract, and reproductive organs. As betel quid contains several neurotoxic ingredients, we hypothesize that it also possesses ototoxicity and may lead to sensorineural hearing impairment (SNHI). In this study, we investigated the contribution of betel quid consumption to SNHI in a large clinical cohort, and validated the pathogenetic mechanisms in ex vivo tissue explants. We enrolled a total of 2364 volunteers, and determined their audiologic results based on Z-scores converted from their original frequency-specific hearing thresholds. Using generalized linear regression, we identified a positive correlation between betel quid consumption and the Z-scores across different frequencies. Subsequently, we explored the toxicity of arecoline, the main neuroactive component of betel quid, on tissue explants from murine cochleae. Arecoline reduced cell activity in the explant cultures and induced apoptosis in the hair cells, probably through the effects of oxidative stress. These findings have expanded the potential hazards of betel quid to common neurological disorders, and provide insights into preventive strategies against SNHI caused by neurotoxic substances.


2013 ◽  
Vol 53 (9) ◽  
pp. 732-735 ◽  
Author(s):  
Kousuke Mori ◽  
Nobuyuki Ishii ◽  
Hitoshi Mochizuki ◽  
Akitoshi Taniguchi ◽  
Kazutaka Shiomi ◽  
...  

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