Vision and Perception Deficits Associated With Dementia

2008 ◽  
Vol 13 (1) ◽  
pp. 4-11
Author(s):  
Monica Robinson
Keyword(s):  
Quality Of Life ◽  
Diabetic Retinopathy ◽  
Low Vision ◽  
The Elderly ◽  
Elderly Individual ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Vision Deficits ◽  
Age Related Changes

Abstract Sensory declines represent a broad category of normal age-related changes that can lead to diminished quality of life for the elderly individual, loss of independence, and increased costs for society as a whole (National Institute of Health, [NIH, 1999). As an individual ages, some of the most prevalent sensory losses are those related to vision and perception. According to the National Eye Institute (NEI, 2004), 3.3 million adult Americans have low vision or blindness and this figure is estimated to increase to 5.5 million by 2020. Vision deficits increase with age; sixty-nine percent of the population who are legally blind are those individuals 80 years old and older. Furthermore, as the population ages, so does the prevalence of multiple age-related diagnoses or conditions that effect vision and/or perception, such as diabetic retinopathy, cataracts, age-related macular degeneration, hemianopsia secondary to a stroke, and dementia.

scholarly journals Bone and Muscle Crosstalk in Aging

2020 ◽  
Vol 8 ◽  
Author(s):  
Chen He ◽  
Wenzhen He ◽  
Jing Hou ◽  
Kaixuan Chen ◽  
Mei Huang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Bone Mineral Density ◽  
Skeletal Muscle ◽  
Bone Cells ◽  
The Elderly ◽  
Extracellular Vesicle ◽  
Mineral Density ◽  
Age Related ◽  
Age Related Changes

Osteoporosis and sarcopenia are two age-related diseases that affect the quality of life in the elderly. Initially, they were thought to be two independent diseases; however, recently, increasing basic and clinical data suggest that skeletal muscle and bone are both spatially and metabolically connected. The term “osteosarcopenia” is used to define a condition of synergy of low bone mineral density with muscle atrophy and hypofunction. Bone and muscle cells secrete several factors, such as cytokines, myokines, and osteokines, into the circulation to influence the biological and pathological activities in local and distant organs and cells. Recent studies reveal that extracellular vesicles containing microRNAs derived from senescent skeletal muscle and bone cells can also be transported and aid in regulating bone-muscle crosstalk. In this review, we summarize the age-related changes in the secretome and extracellular vesicle-microRNAs secreted by the muscle and bone, and discuss their interactions between muscle and bone cells during aging.

scholarly journals Four Years of Observation to Evaluate Autonomy and Quality of Life after Implantation of a High-Add Intraocular Lens in Age-Related Macular Degeneration Patients

2020 ◽  
Vol 11 (2) ◽  
pp. 448-456
Author(s):  
Andreas F. Borkenstein ◽  
Eva-Maria Borkenstein
Keyword(s):  
Quality Of Life ◽  
Visual Acuity ◽  
Low Vision ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Corrected Distance Visual Acuity ◽  
Near Visual Acuity ◽  
Dry Amd

Visual impairment resulting from advanced dry age-related macular degeneration (AMD) limits the ability to perform activities required for independent living and adversely affects quality of life. We aimed to determine changes in these parameters in patients with AMD-related geographic atrophy who underwent magnifying cataract surgery (MAGS) using a foldable, bifocal high-add intraocular lens (IOL). The high-add IOL (LENTIS® MAX LS-313 MF 80, Oculentis) was implanted in the better seeing or dominant eye of eligible patients with clinically significant cataract, best corrected distance visual acuity 1.3–0.5 logMAR (20/400–20/63), best corrected near visual acuity >0.8 logMAR (20/125), and stable advanced dry AMD. Self-reported feasibility of performing routine activities and change in quality of life were the main outcome measures. Eleven of 15 operated patients had complete follow-up to 48 months. There were no significant intraoperative or postoperative complications. AMD converted from dry to wet in 2 patients. All patients reported functional gains in the first 3–6 months after surgery, and 10/11 patients reported improved quality of life. From baseline to 48 months, functional performance remained improved in all patients, and quality of life remained improved in the 9 patients with stable AMD. Best corrected distance visual acuity and uncorrected near visual acuity improved in all cases after surgery. Conclusion: Implantation of the high-add IOL was safe and resulted in durable functional and quality of life benefits. To our knowledge, our report describes the longest prospective follow-up (4 years) of a series of patients undergoing MAGS for rehabilitation of low vision related to advanced AMD. Data are needed from larger cohorts, but our experience supports giving consideration to MAGS in appropriately selected patients with low vision related to advanced dry AMD. We encourage further industry development of this technology and additional clinical research to collect more outcomes data to determine its potential to help patients maintain highly valued autonomy and quality of life.

scholarly journals The implantable miniature telescope

2015 ◽  
Vol 84 (2) ◽  
pp. 26-28
Author(s):  
Phillip Williams ◽  
Steven Wong
Keyword(s):  
Quality Of Life ◽  
The Elderly ◽  
The United States ◽  
Poor Quality ◽  
Current Treatment ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
End Stage ◽  
Implantable Miniature Telescope

Bilateral, end-stage, age-related macular degeneration (AMD) is a devastating condition of the eye. As the leading cause of blindness worldwide in the elderly, it leads to poor quality of life. While antivascular endothelium growth factor agents are used as front-line treatment for wet AMD, no current treatment exists for bilateral, end-stage AMD in Canada. The implantable miniature telescope (IMT), approved by the Food and Drug Administration in 2010, is a treatment option available for those over the age of 65 in the United States with stable severe to profound vision impairment (best-corrected visual acuity 20/160 to 20/800) caused by bilateral central scotomas associated with bilateral, end-stage AMD. Combining the fields of engineering and ophthalmology, intraocular implantation of the IMT provides improvements in patients’ functional vision and quality of life. As a relatively new treatment targeting the elderly, there are strict inclusion criteria as well as risks associated with the procedure. However, research and continuing development in this field is ongoing to minimize these risks.

scholarly journals Monitoring Health Parameters of Elders to Support Independent Living and Improve Their Quality of Life

Sensors ◽  
2021 ◽  
Vol 21 (2) ◽  
pp. 517
Author(s):  
Ilia Adami ◽  
Michalis Foukarakis ◽  
Stavroula Ntoa ◽  
Nikolaos Partarakis ◽  
Nikolaos Stefanakis ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Independent Living ◽  
Elderly Population ◽  
Well Being ◽  
The Elderly ◽  
Chronic Illnesses ◽  
Age Related ◽  
Self Sufficiency ◽  
Health And Well Being

Improving the well-being and quality of life of the elderly population is closely related to assisting them to effectively manage age-related conditions such as chronic illnesses and anxiety, and to maintain their independence and self-sufficiency as much as possible. This paper presents the design, architecture and implementation structure of an adaptive system for monitoring the health and well-being of the elderly. The system was designed following best practices of the Human-Centred Design approach involving representative end-users from the early stages.

scholarly journals Medication adherence and quality of life among the elderly with diabetic retinopathy

2014 ◽  
Vol 22 (6) ◽  
pp. 902-910 ◽  
Author(s):  
Fernanda Freire Jannuzzi ◽  
Fernanda Aparecida Cintra ◽  
Roberta Cunha Matheus Rodrigues ◽  
Thaís Moreira São-João ◽  
Maria Cecília Bueno Jayme Gallani
Keyword(s):  
Quality Of Life ◽  
Adverse Event ◽  
Diabetic Retinopathy ◽  
Medication Adherence ◽  
The Elderly ◽  
Oral Antidiabetics ◽  
Elderly Outpatients ◽  
Treatment Of Diabetes ◽  
Morisky Scale

METHOD: one hundred (n=100) elderly outpatients with diabetic retinopathy taking antihypertensives and/or oral antidiabetics/insulin were interviewed. Adherence was evaluated by the adherence proportion and its association with the care taken in administrating medications and by the Morisky Scale. The National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) was used to evaluate HRQoL.RESULTS: most (58%) reported the use of 80% or more of the prescribed dose and care in utilizing the medication. The item "stopping the drug when experiencing an adverse event", from the Morisky Scale, explained 12.8% and 13.5% of the variability of adherence proportion to antihypertensives and oral antidiabetics/insulin, respectively.CONCLUSION: there was better HRQoL in the Color Vision, Driving and Social Functioning domains of the NEI VFQ-25. Individuals with lower scores on the NEI VFQ-25 and higher scores on the Morisky Scale presented greater chance to be nonadherent to the pharmacological treatment of diabetes and hypertension.

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