scholarly journals Vascular biomedicine in an era of chronic disease and multimorbidity

2019 ◽  
Vol 133 (9) ◽  
pp. 1137-1143 ◽  
Author(s):  
Gemma Currie ◽  
Christian Delles
Keyword(s):  
Heart Failure ◽  
Chronic Disease ◽  
Cardiovascular Diseases ◽  
Clinical Science ◽  
Renal Diseases ◽  
Healthcare Provision ◽  
Research Papers ◽  
New Models ◽  
Complex Features

Abstract It is increasingly common that patients present with more than one disease and that diseases are chronic in nature. Cardiovascular conditions such as hypertension, heart failure and stroke, renal diseases and cardiometabolic conditions such as diabetes are prime examples of chronic diseases which pose major challenges in contemporary healthcare provision. The complex features of multimorbidity call for precision medicine approaches that take comorbidity and chronicity into account. The research basis of chronic disease and multimorbidity, however, is currently in its infancy. This applies to all domains including basic, translational and clinical science. In this article we call for development of new models, smarter use of existing models and better characterisation of vascular and cardiovascular phenotypes in studies not directly related to cardiovascular diseases. This has the potential to further improve the quality of translational research, papers in journals such as Clinical Science and ultimately translate into better patient care.

Quality of life in chronic disease: a comparison between patients with heart failure and patients with aphasia after stroke

2010 ◽  
Vol 19 (13-14) ◽  
pp. 1855-1860 ◽  
Author(s):  
Åsa Franzén-Dahlin ◽  
Monica Rydell Karlsson ◽  
Märit Mejhert ◽  
Ann-Charlotte Laska
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Chronic Disease ◽  
Patients With Heart Failure

scholarly journals Socioeconomic Inequalities in Health-Related Quality of Life among Patients with Cardiovascular Diseases in Vietnam

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Bach Xuan Tran ◽  
Mackenzie PI Moir ◽  
Thao Phuong Thi Thai ◽  
Long Hoang Nguyen ◽  
Giang Hai Ha ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Disease ◽  
Cardiovascular Diseases ◽  
Chronic Disease Management ◽  
Management Program ◽  
Sociodemographic Characteristics ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Purpose. This study aims to explore the sociodemographic differences in health-related quality of life (HRQOL) among Vietnamese patients with cardiovascular diseases (CVD). Methods. A cross-sectional survey of 600 cardiovascular disease patients (300 inpatients and 300 outpatients) being treated at the Hanoi Heart Hospital was completed between July and December 2016. Data about HRQOL were collected by using the EuroQol-5 Dimensions-5 Levels (EQ-5D-5L) and EuroQOL-visual analogue scale (VAS). Sociodemographic characteristics were collected. A multivariate Tobit regression was used to detect the correlations between HRQOL and sociodemographic factors. Results. Our sample had an average EQ-5D index of 0.82 (SD=0.21) and VAS score of 77.8 (SD=13.6). Participants were most likely to report problems in pain/discomfort (38.8%) and anxiety/depression (35.2%) and were least likely to report problems related to self-care (19.8%). Age and sex were strongly associated with the EQ-5D index and the VAS. Having health insurance and the number of hospital visits were negatively associated with HRQOL, while participation in the chronic disease management program had the positive relationship. Conclusions. HRQOL among patients with CVD was moderately lower compared to the Vietnamese general population. Sociodemographic characteristics were strongly associated with HRQOL suggesting that addressing these inequalities should be prioritized in delivering services. Patients should also be encouraged to participate in the chronic disease management program due to its positive effects on quality of life.

scholarly journals Cardiovascular diseases in patients with chronic renal diseases

2008 ◽  
Vol 136 (Suppl. 2) ◽  
pp. 135-141 ◽  
Author(s):  
Nada Dimkovic
Keyword(s):  
Heart Failure ◽  
Cardiovascular Diseases ◽  
General Population ◽  
Renal Disease ◽  
Left Ventricular ◽  
Silent Myocardial Ischemia ◽  
Renal Diseases ◽  
Cerebrovascular Event ◽  
Cardiovascular Morbidity And Mortality ◽  
Chronic Renal Diseases

The risk of cardiovascular disease in patients with chronic renal disease appears to be far greater than in the general population and the risk of cardiovascular death is much higher than the risk of eventually requiring renal replacement therapy. Heart failure is important finding and it is evident even before the initiation of dialysis; the frequency of heart failure is 10 to 30 times higher in patients on dialysis than in the general population. Left ventricular hypertrophy has incidence of nearly 75-80% and is closely related to heart failure, ventricular arrhythmias, fatal myocardial infarction, aortic root dilatation and cerebrovascular event. Ischaemic heart disease is usually the consequence of coronary artery disease, but 27% of haemodialysis patients may have symptoms without atherosclerotic changes in coronary arteries. Silent myocardial ischemia is more frequent in dialysis population. Hypertension is present in 80-85% of patients and its prevalence is linearly related to glomerular filtration rate. Patients with end-stage renal disease are more likely to have an increase in pulse pressure and isolated systolic hypertension and they may not demonstrate the normal nocturnal decline in blood pressure. Patients on dialysis are prone to calcification of media and intima due to disbalance of promoters and inhibitors of calcification process. Now, there are no valid data about the privilege of one dialysis method over another in cardiovascular morbidity and mortality. Numerous traditional and non-traditional risk factors urge for preventive measures for cardiovascular diseases in patients with chronic renal diseases.

Advanced Heart Failure Management and Selection for Advanced Therapies

2015 ◽  
pp. 216-235
Author(s):  
Alexander Papolos ◽  
Nishant A. Gandhi ◽  
Elrond Teo ◽  
Raymond Bietry
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Chronic Disease ◽  
Cardiac Transplantation ◽  
Advanced Heart Failure ◽  
Therapeutic Window ◽  
Circulatory Support ◽  
Narrow Therapeutic Window ◽  
Advanced Therapies

Advancements in the field of heart failure have significantly improved both mortality and the quality of life of millions. However, heart failure generally remains a chronic disease with an insidious progression to organ failure despite optimal medical treatment. Early consideration of advanced therapies such as mechanical circulatory support and cardiac transplantation in advanced heart failure is essential. The purpose of this chapter is to assist the reader in the identification of patients with advanced heart failure that have not yet developed irreversible end-organ dysfunction, as interventions in this narrow therapeutic window results in improved post-surgical outcomes.

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