Colonic acetate in obesity: location matters!

2016 ◽  
Vol 130 (22) ◽  
pp. 2083-2086 ◽  
Author(s):  
Laure B. Bindels ◽  
Isabelle Leclercq
Keyword(s):  
Fatty Acids ◽  
Animal Models ◽  
Short Chain Fatty Acids ◽  
Host Immunity ◽  
Short Chain ◽  
Therapeutic Application ◽  
Complex Interactions ◽  
Micro Organisms ◽  
By Products ◽  
Chain Fatty Acids

Gut micro-organisms are recognized as crucial regulators of host immunity and the microbiota has been implicated in several inflammatory, immune, inflammatory or even psychiatric disorders. Therefore the analysis of the complex interactions between gut microbiota and the host is currently under intense investigation. Most of our knowledge stems from the study of animal models while translational research and data in humans are necessary to move the field forward and to evolve to diagnostic and therapeutic application. Amongst the microbial by-products, short chain fatty acids such as acetate yielded by fermentation of non-digestible fibers, were pointed as metabolic modulators. Here we highlight a study evaluating the effects of colonic infusion of one of the short chain fatty acids, acetate, in a cohort of overweight and obese normoglycaemic subjects.

scholarly journals Improving the Viability and Metabolism of Intestinal Probiotic Bacteria Using Fibre Obtained from Vegetable By-Products

Foods ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 2113
Author(s):  
María Ángeles Rivas ◽  
María José Benito ◽  
Santiago Ruíz-Moyano ◽  
Alberto Martín ◽  
María de Guía Córdoba ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Gastrointestinal Transit ◽  
Value Added ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
In Vitro Test ◽  
Probiotic Strains ◽  
By Products ◽  
Chain Fatty Acids

This study evaluated the effect of dietary fibre obtained from pomegranate, tomato, grape and broccoli by-products on the gastrointestinal transit survival, growth, and metabolism of six probiotic strains. The results showed that the studied by-products contained variable amounts of polysaccharides that affected the six probiotic microorganisms in different ways. In addition, the protective effect of the fibre obtained on the probiotic strains was more effective in the case of the fibre obtained from tomato peel. In terms of growth, grape stems showed the best results, favouring the growth of lactic acid bacteria. Finally, all fibres were able to increase the content of short-chain fatty acids in the in vitro test, but broccoli stems and pomegranate peel stimulated higher production of short-chain fatty acids. The results of this study demonstrate that plant by-product fibres can improve survival, growth, and metabolism in terms of the fatty acid profiles of probiotic strains, highlighting the desirability of harnessing these by-product fibres to develop new high-value-added ingredients as probiotic carriers.

The additivity of predicted ATP yields from feedstuffs incubated in vitro with rumen fluid

2000 ◽  
Vol 2000 ◽  
pp. 25-25 ◽  
Author(s):  
A.R. Moss ◽  
C. Rymer ◽  
S. Fakhri ◽  
D.I. Givens
Keyword(s):  
Fatty Acids ◽  
Microbial Biomass ◽  
Rumen Fluid ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
The Individual ◽  
Micro Organisms ◽  
Chain Fatty Acids

Rumen micro-organisms ferment feeds to short chain fatty acids (SCFA) with the production of ATP. Measuring SCFA concentration in vitro could therefore be used to predict the yield of ATP in vitro. This estimate could then be used to predict the yield of synthesised microbial biomass. However, feeds may interact when they are incubated together, and so it is quite possible that ATP yield is not additive. The objectives of this experiment were therefore to determine whether the yield of total SCFA produced by feed mixtures was additive, and also whether the ATP yield of feed mixtures could be predicted from the calculated ATP yield of the individual feeds.

Effect of short-chain fatty acids on the ethylene pathway in embryonic axes of Cicer arietinum during germination

1994 ◽  
Vol 92 (4) ◽  
pp. 629-635 ◽  
Author(s):  
Mercedes Gallardo ◽  
Paloma Munoz De Rueda ◽  
Angel Jesus Matilla ◽  
Isabel Maria Sanchez-Calle
Keyword(s):  
Fatty Acids ◽  
Cicer Arietinum ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Embryonic Axes ◽  
Chain Fatty Acids

Short-Chain Fatty Acids Prevent Diabetic Nephropathy In Vivo and In Vitro

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 92-OR ◽  
Author(s):  
WEI HUANG ◽  
YONG XU ◽  
YOUHUA XU ◽  
LUPING ZHOU ◽  
CHENLIN GAO
Keyword(s):  
Fatty Acids ◽  
Diabetic Nephropathy ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Fatty Acids

1898-P: Colonic Short-Chain Fatty Acids Lower Endogenous Glucose Production

Diabetes ◽  
2020 ◽  
Vol 69 (Supplement 1) ◽  
pp. 1898-P
Author(s):  
ADELINA I.L. LANE ◽  
SAVANNA N. WENINGER ◽  
FRANK DUCA
Keyword(s):  
Fatty Acids ◽  
Glucose Production ◽  
Short Chain Fatty Acids ◽  
Endogenous Glucose Production ◽  
Short Chain ◽  
Endogenous Glucose ◽  
Chain Fatty Acids

Concentrations and Correlations of Faecal Short-chain Fatty Acids and Faecal Water Content in Man

1994 ◽  
Vol 7 (6) ◽  
Author(s):  
U. Siigur ◽  
K. E. Norin ◽  
G. Allgood ◽  
T. Schlagheck ◽  
Tore Midtvedt
Keyword(s):  
Fatty Acids ◽  
Water Content ◽  
Short Chain Fatty Acids ◽  
Short Chain ◽  
Chain Fatty Acids
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