scholarly journals Alveolar T-helper type-2 immunity in atopic asthma is associated with poor clinical control

2014 ◽  
Vol 128 (1) ◽  
pp. 47-56 ◽  
Author(s):  
Anders Bergqvist ◽  
Cecilia K. Andersson ◽  
Michiko Mori ◽  
Andrew F. Walls ◽  
Leif Bjermer ◽  
...  
Keyword(s):  
Asthma Control ◽  
Atopic Asthma ◽  
T Helper ◽  
Type 2 Immunity ◽  
Clinical Control ◽  
Alveolar Parenchyma ◽  
Helper Type

Many patients with asthma remain symptomatic despite treatment with conventional ICSs. The present study shows a link between poor asthma control and a Th2-skewed immunity in the alveolar parenchyma, a region not reached by conventional ICSs.

scholarly journals Basophils as a primary inducer of the T helper type 2 immunity in ovalbumin-induced allergic airway inflammation

Immunology ◽  
2014 ◽  
Vol 142 (2) ◽  
pp. 202-215 ◽  
Author(s):  
Wenwei Zhong ◽  
Wen Su ◽  
Yanjie Zhang ◽  
Qi Liu ◽  
Jinhong Wu ◽  
...  
Keyword(s):  
Airway Inflammation ◽  
Allergic Airway Inflammation ◽  
T Helper ◽  
Type 2 Immunity ◽  
Helper Type
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