Non-invasive measurement of cardiac output in heart failure patients using a new foreign gas rebreathing technique

2002 ◽  
Vol 102 (2) ◽  
pp. 247 ◽  
Author(s):  
Anders GABRIELSEN ◽  
Regitze VIDEBÆK ◽  
Morten SCHOU ◽  
Morten DAMGAARD ◽  
Jens KASTRUP ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiac Output ◽  
Heart Failure Patients ◽  
Non Invasive ◽  
Invasive Measurement

Non-invasive measurement of cardiac output during exercise in chronic heart failure

2005 ◽  
Vol 12 (3) ◽  
pp. 298-299
Author(s):  
Gaia Cattadori ◽  
Piergiuseppe Agostoni ◽  
Anna Apostolo ◽  
Giancarlo Marenzi
Keyword(s):  
Heart Failure ◽  
Cardiac Output ◽  
Chronic Heart Failure ◽  
Non Invasive ◽  
Invasive Measurement

Non-invasive measurement of cardiac output in patients with chronic heart failure

2004 ◽  
Vol 9 (5) ◽  
pp. 277-280 ◽  
Author(s):  
Stephen J. Leslie ◽  
Sin??ad McKee ◽  
David E. Newby ◽  
David J. Webb ◽  
Martin A. Denvir
Keyword(s):  
Heart Failure ◽  
Cardiac Output ◽  
Chronic Heart Failure ◽  
Non Invasive ◽  
Invasive Measurement

Usefulness of Non-Invasive Measurement of Cardiac Output During Sub-Maximal Exercise to Predict Outcome in Patients With Chronic Heart Failure

2009 ◽  
Vol 104 (11) ◽  
pp. 1556-1560 ◽  
Author(s):  
Ayumi Goda ◽  
Chim C. Lang ◽  
Paula Williams ◽  
Margaret Jones ◽  
Mary Jane Farr ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiac Output ◽  
Chronic Heart Failure ◽  
Maximal Exercise ◽  
Non Invasive ◽  
Invasive Measurement

Non-invasive measurement of stroke volume during exercise in heart failure patients

2000 ◽  
Vol 98 (5) ◽  
pp. 545 ◽  
Author(s):  
Pier Giuseppe AGOSTONI ◽  
Karlman WASSERMAN ◽  
Giovanni B. PEREGO* ◽  
Marco GUAZZI* ◽  
Gaia CATTADORI* ◽  
...  
Keyword(s):  
Heart Failure ◽  
Stroke Volume ◽  
Heart Failure Patients ◽  
Non Invasive ◽  
Invasive Measurement

Non-invasive measurement of cardiac output in heart failure patients using a new foreign gas rebreathing technique

2002 ◽  
Vol 102 (2) ◽  
pp. 247-252 ◽  
Author(s):  
Anders GABRIELSEN ◽  
Regitze VIDEBÆK ◽  
Morten SCHOU ◽  
Morten DAMGAARD ◽  
Jens KASTRUP ◽  
...  
Keyword(s):  
Heart Failure ◽  
Cardiac Output ◽  
Reliable Estimate ◽  
Shunt Flow ◽  
Heart Failure Patients ◽  
Non Invasive ◽  
Patients With Heart Failure ◽  
Flow Through ◽  
The Mean ◽  
Rebreathing Method

Values of effective pulmonary blood flow (QEP) and cardiac output, determined by a non-invasive foreign gas rebreathing method (CORB) using a new infrared photoacoustic gas analysing system, were compared with measurements of cardiac output obtained by the direct Fick (COFICK) and thermodilution (COTD) methods in patients with heart failure or pulmonary hypertension. In 11 patients, of which three had shunt flow through areas without significant gas exchange, the mean difference (bias) and limits of agreement (±2S.D.) were 0.6±1.2litreċmin-1 when comparing COFICK and QEP, and -0.8±1.3litreċmin-1 when comparing COFICK and COTD. When correction for intrapulmonary shunt flow was applied (i.e. calculation of CORB) in all 11 patients, the bias between COFICK and CORB was 0.1±0.9litreċmin-1, primarily because agreement improved in the three patients with significant shunt flow. In the eight patients without significant shunt flow, the agreement between QEP and COFICK was 0.3±0.9litreċmin-1. In conclusion, a foreign gas rebreathing method with a new infrared photoacoustic gas analyser provided at least as reliable a measure of cardiac output as did thermodilution. In the absence of significant shunt flow, measurement of QEP itself provides a reliable estimate of cardiac output in heart failure patients. The infrared photoacoustic gas analyser markedly facilitates clinical use of the rebreathing method in general, which makes the method available to a larger group of clinicians working with patients with cardiovascular diseases.

scholarly journals 568 Echocardiography and impedance cardiography as determinants of successful slow Levosimendan infusion in patients with acute advanced heart failure

2021 ◽  
Vol 23 (Supplement_G) ◽  
Author(s):  
Gaetano Ruocco ◽  
Guido Pastorini ◽  
Mauro Feola
Keyword(s):  
Heart Failure ◽  
Cardiac Output ◽  
Speckle Tracking ◽  
Longitudinal Strain ◽  
Impedance Cardiography ◽  
Global Longitudinal Strain ◽  
Advanced Heart Failure ◽  
Non Invasive ◽  
Dimensional Echocardiography ◽  
Invasive Measurement

Abstract Aims Despite new therapeutic options, patients with heart failure (HF) still progress to advanced stage. Among new therapeutic options, Levosimendan was recently approved in order to treat patients hospitalized for acute decompensated heart failure (ADHF) with severe systolic dysfunction. The pharmacological effects of Levosimendan consist of inotropy, vasodilatation, and cardioprotection through the increase of calcium sensitivity. These effects should be monitored with echocardiography and in particular with speckle tracking and tri-dimensional echocardiography which appear to be useful in LV systolic function detection and monitoring. In this study we aim to evaluate the effect of slow infusion of Levosimendan on the non-invasive measurement of cardiac output, the speckle tracking parameters and the tri-dimensional echocardiography measurements in advanced ADHF patients. Methods and results This is a prospective observational study evaluating Levosimendan efficacy through advanced echocardiography. We enrolled 11 patients with diagnosis of ADHF who respect the recent ESC criteria of ‘advanced heart failure’. Patients underwent to blood sample examination to measure electrolytes, creatinine, and NTproBNP. Patients underwent to advanced echocardiography examination (performed for each patient pre- and post-Levosimendan infusion) with tri-dimensional echocardiography and global longitudinal strain assessment. Furthermore patients underwent to non-invasive cardiac output and cardiac index collection through impedance cardiography pre- and post-Levosimendan infusion. All patients were followed for 30 days after discharge for all cause of mortality and HF re-hospitalization. A total of 11 patients affected by advanced ADHF were included in this study. Mean age was 73.8 ± 4.7 years. 72.7% (n 8) patients were men. 81.9% (n 9) of patients recognize ischaemic heart disease as HF etiology. At admission mean systolic arterial pressure was 100 ± 17 mmHg, mean NTproBNP was 24 445 ± 12 194 pg/ml and mean serum creatinine was 1.55 ± 0.84 mg/dl. At tri-dimensional echocardiography mean LV ejection fraction (LVEF) was 19.7 ± 5.7% and at bi-dimensional echocardiography mean tricuspid anular plane systolic excursion (TAPSE) and pulmonary arterial systolic pressure (PASP) were, respectively, 12.5 ± 2.7 mm and 48 ± 16 mmHg. Mean LV global longitudinal strain (GLS) was −3.0 ± 1.8. Mean furosemide in-hospital infusion was 306 ± 102 mg/die and mean urine output 1436 ± 496 ml. None developed significant ventricular or supraventricular arrhythmias. All patients were treated with betablockers during infusion. At 30 days of follow-up two patients died and 1 patient was re-hospitalized. Evaluating the differences among our variables pre- and post-Levosimendan infusion, we found that NTproBNP was significantly reduced post-Levosimendan infusion (P = 0.01). Among ICG non-invasive measurement, we found significant differences in stroke volume (SV) and cardiac output (CO) in terms of significant improvement (P = 0.001 for both). Analysing tri-dimensional echocardiography variables, we observed a significant improvement of LVEF (P = 0.003), SV (P = 0.03) and 3-D LV GLS (P = 0.002). Furthermore, we observed a significant reduction in end-systolic volume (ESV) post-Levosimendan infusion (P = 0.02). Among bi-dimensional echocardiography measurements, there was a significant reduction in end-diastolic diameter of right ventricle (EDDRV) and in B-lines count (respectively, P = 0.02 and P = 0.002). Moreover, we observed a significant improvement in TAPSE (P = 0.003) and in LV GLS (P = 0.004). Conclusions Our study showed that slow Levosimendan infusion (12.5 mg at velocity of 0.05–1 mcg/kg/min) without bolus could be considered in advanced ADHF patients to improve cardiac performance without severe adverse events. ICG and echocardiography in-hospital evaluation seemed to be necessary to understand treatment success and patients status improvement as well as cardiac function benefit.

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