Possible interaction between exposure to environmental tobacco smoke and therapy in children with asthma

1998 ◽  
Vol 95 (2) ◽  
pp. 143 ◽  
Author(s):  
Jean-Christophe DUBUS ◽  
Christiane ODDOZE ◽  
Monique BADIER ◽  
Chantal GUILLOT ◽  
Bernard BRUGUEROLLE
Keyword(s):  
Environmental Tobacco Smoke ◽  
Tobacco Smoke ◽  
Children With Asthma

scholarly journals Environmental Tobacco Smoke and Behaviors of Inner-City Children With Asthma

2008 ◽  
Vol 8 (5) ◽  
pp. 288-293 ◽  
Author(s):  
Maria Fagnano ◽  
Kelly M. Conn ◽  
Jill S. Halterman
Keyword(s):  
Inner City ◽  
Environmental Tobacco Smoke ◽  
Tobacco Smoke ◽  
Children With Asthma ◽  
And Behaviors

A Controlled Trial of an Environmental Tobacco Smoke Reduction Intervention in Low-Income Children With Asthma

CHEST Journal ◽  
2001 ◽  
Vol 120 (5) ◽  
pp. 1709-1722 ◽  
Author(s):  
Sandra R. Wilson ◽  
Eileen G. Yamada ◽  
Reddivalam Sudhakar ◽  
Lauro Roberto ◽  
David Mannino ◽  
...  
Keyword(s):  
Environmental Tobacco Smoke ◽  
Tobacco Smoke ◽  
Low Income ◽  
Controlled Trial ◽  
Low Income Children ◽  
Children With Asthma

Environmental tobacco smoke and its effect on the symptoms and medication in children with asthma

2009 ◽  
Vol 19 (2) ◽  
pp. 97-108 ◽  
Author(s):  
Akira Yamasaki ◽  
Keichi Hanaki ◽  
Katsuyuki Tomita ◽  
Masanari Watanabe ◽  
Yasuyuki Hasagawa ◽  
...  
Keyword(s):  
Environmental Tobacco Smoke ◽  
Tobacco Smoke ◽  
Children With Asthma

scholarly journals Screening for Environmental Tobacco Smoke Exposure Among Inner-City Children With Asthma

PEDIATRICS ◽  
2008 ◽  
Vol 122 (6) ◽  
pp. 1277-1283 ◽  
Author(s):  
J. S. Halterman ◽  
B. Borrelli ◽  
P. Tremblay ◽  
K. M. Conn ◽  
M. Fagnano ◽  
...  
Keyword(s):  
Inner City ◽  
Environmental Tobacco Smoke ◽  
Tobacco Smoke ◽  
Environmental Tobacco Smoke Exposure ◽  
Smoke Exposure ◽  
Tobacco Smoke Exposure ◽  
Children With Asthma

Possible interaction between exposure to environmental tobacco smoke and therapy in children with asthma

1998 ◽  
Vol 95 (2) ◽  
pp. 143-149 ◽  
Author(s):  
Jean-Christophe DUBUS ◽  
Christiane ODDOZE ◽  
Monique BADIER ◽  
Chantal GUILLOT ◽  
Bernard BRUGUEROLLE
Keyword(s):  
Environmental Tobacco Smoke ◽  
Tobacco Smoke ◽  
Fold Increase ◽  
Bronchial Reactivity ◽  
Urinary Cotinine ◽  
Bronchodilator Response ◽  
Doubling Dose ◽  
Children With Asthma ◽  
Anti Inflammatory ◽  
The Difference

1.The aim of the study was to determine the carbachol and albuterol responsiveness in treated and untreated asthmatic and allergic children exposed to environmental tobacco smoke assessed by urinary cotinine measurements. 2.Forty-six asthmatic and allergic children with normal spirometric values were recruited. The doubling dose, concentration of carbachol producing a 2-fold increase in specific airway resistance (SRaw) was determined and 200 ;μg of albuterol were administered via a Volumatic® spacer. The percentage of bronchodilatation was defined as the difference between the largest obtained SRaw and the post-β2 SRaw divided by the largest SRaw. Data were compared by a Mann–Whitney U-test. 3.The 23 children with a high urinary cotinine, compared with the 23 children without urinary cotinine, had a decreased doubling dose (108.2±14.7 ;μg versus 160.9±19.5 ;μg; P = 0.04) and an increased percentage of bronchodilatation (74.8±1.4% versus 68.8±1.8%; P = 0.03). A prophylactic anti-inflammatory treatment induced a weaker bronchial reactivity to carbachol and a slightly greater bronchodilatation in children exposed to environmental tobacco smoke. 4.Environmental tobacco smoke increases bronchial reactivity in asthmatic and allergic children. This effect might be reduced by anti-inflammatory therapy. The bronchodilator response may be enhanced in exposed children and may be caused by one or several direct interactions between tobacco smoke compounds and albuterol.

Effectiveness of ongoing face-to-face anti-tobacco intervention in children with asthma

2020 ◽  
Vol 41 (3) ◽  
pp. 198-203
Author(s):  
M. Bobrowska-Korzeniowska ◽  
J. Jerzyńska ◽  
M. Mitał ◽  
D. Podlecka ◽  
A. Brzozowska ◽  
...  
Keyword(s):  
Environmental Tobacco Smoke ◽  
Tobacco Smoke ◽  
Tobacco Smoking ◽  
Active Group ◽  
Control Group ◽  
Face To Face ◽  
Active Intervention ◽  
Quit Smoking ◽  
Children With Asthma ◽  
Tobacco Intervention

Background: Interventions to help parents quit smoking may yield important benefits for children with asthma. Children’s exposure to environmental tobacco smoke can be measured by reporting of an adult in the household and testing the child’s biomarker, e.g., cotinine. Objective: The aim of the study was to assess the effectiveness of “face-to-face” intervention carried out since 2016 in families with children diagnosed with asthma 3 years after beginning the anti-tobacco intervention. Methods: This study was a follow-up to an interventional study that assessed the effectiveness of direct patient education versus educational leaflets alone about parental tobacco smoking. The patients with asthma (ages 4‐17 years) enrolled in our original intervention study conducted in 2016 were under the care of the allergy outpatient clinic. The active group was individually educated about the harmful effects of environmental tobacco smoke on their children. The control group included patients and parents, among whom only leaflets were distributed. After 3 years of ongoing intervention, in patients from both groups, exposure to tobacco smoking was evaluated with a questionnaire addressed to parents and/or caregivers and measurement of cotinine in children’s urine. The forced expiratory volume in the first second of expiration and fractional exhaled nitric oxide levels were measured. Results: Seventy participants completed the study: 37 in the active group and 33 in the control group. In the active group, 27% of the parents quit smoking entirely compared with 9.4% of parents in the control group. In the group of active intervention, a significant decrease in the cotinine level (p < 0 .001) and the number of cigarettes smoked daily were observed (p < 0.001) 3 years after the active intervention compared with values right after the intervention. In the control group, there were no significant changes in the above-mentioned parameters. Conclusion: “Face-to-face” intervention among families with smokers were effective and lowered cotinine levels in children with asthma and the number of cigarettes smoked assessed 3 years after the intervention.

scholarly journals Spirometric changes in children with asthma exposed to environmental tobacco smoke and treated with inhaled corticosteroids

2019 ◽  
Vol 76 (3) ◽  
pp. 321-330
Author(s):  
Snezana Radic ◽  
Branislava Milenkovic ◽  
Branislav Gvozdenovic ◽  
Biljana Medjo ◽  
Sanja Dimic-Janjic
Keyword(s):  
Lung Function ◽  
Fluticasone Propionate ◽  
Environmental Tobacco Smoke ◽  
Tobacco Smoke ◽  
Inhaled Corticosteroids ◽  
Persistent Asthma ◽  
Forced Expiratory Volume ◽  
The Family ◽  
Lower Lung ◽  
Children With Asthma

Background/Aim. Corticosteroids are the most frequently prescribed anti-inflammatory treatment in asthma. A purpose of this study was to compare the spirometric parameters as a response to inhaled fluticasone propionate (FP) treatment in children with asthma, exposed and nonexposed to environmental tobacco smoke (ETS). Methods. The study included 527 children aged between 1 and 16 years with persistent asthma divided into the groups of ETS exposed (ETSE, n = 337) and ETS free (ETSF, n = 190) children. Spirometry was performed before (1st set of results) and after 6 months of FP treatment (2nd set of results). Good lung function (GLF) was defined as forced expiratory volume in one second (FEV1) ? 85%, and ?poor lung function? (PLF) as FEV1 < 85%. Results. Among the ETSE children, 208 had one smoking parent, 129 had two, 228 had smoking mothers and 238 smoking fathers. The ETSE children received a higher FP dose (p < 0.0001) which was increased with the increase of the number of smokers in the family. The ETSE children had significantly lower lung function both in the 1st and 2nd sets of tests compared to the ETSF children (p < 0.05). After the FP treatment, both groups improved all spirometric parameters (p < 0.001). In the 2nd set of the spirometric tests, the children of smoking mothers had lower spirometry values compared to the children of smoking fathers (p < 0.05). The proportion of the children improving from the PLF to GLF after 6 months of FP was much higher among the ETSF than the ETSE children (p < 0.05). Conclusions. The ETSE children had lower spirometric values before FP. After 6-months of the FP treatment children in both groups improved the spirometric values, but the improvement was higher in the ETSF children.

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