Relationship of skeletal muscle mass, muscle strength and bone mineral density in adults with cystic fibrosis

2000 ◽  
Vol 99 (4) ◽  
pp. 309-314 ◽  
Author(s):  
Sarah L. ELKIN ◽  
Lauren WILLIAMS ◽  
Margaret MOORE ◽  
Margaret E. HODSON ◽  
Olga M. RUTHERFORD
Keyword(s):  
Bone Mineral Density ◽  
Cystic Fibrosis ◽  
Muscle Strength ◽  
Muscle Mass ◽  
Bone Mineral ◽  
Significant Relationship ◽  
Mineral Density ◽  
Peripheral Muscle ◽  
Leg Muscle ◽  
Total Body

Few studies have investigated peripheral muscle strength and quality in patients with cystic fibrosis (CF). The present study tested the isometric and isokinetic strength of the quadriceps and hamstrings using an isokinetic dynamometer and a strength-testing chair in 25 CF adults and 25 controls. Total body and leg muscle mass were determined by dual-energy X-ray absorptiometry, and bone mineral density (BMD) was also measured. Both muscle strength and muscle mass (total body and leg) were decreased in the CF group. In both groups there was a highly significant relationship between quadriceps strength and leg muscle mass (CF, r = 0.7, P = 0.0002; controls, r = 0.6, P = 0.0013). When strength was normalized for muscle size, there was no significant difference between the two groups. Total body and leg BMD were significantly reduced in CF subjects compared with controls. However, when corrected for height, the differences disappeared. There was a significant relationship found between leg muscle mass and leg BMD. We conclude that CF adults are significantly weaker than controls. This is due to lower muscle mass, and not to a reduced force-generating capacity of the muscle, implying that there is no decrease in the quality of CF muscle. BMD is also reduced in CF subjects, and this appears to be related to shorter stature in this group.

Relationship of skeletal muscle mass, muscle strength and bone mineral density in adults with cystic fibrosis

2000 ◽  
Vol 99 (4) ◽  
pp. 309 ◽  
Author(s):  
Sarah L. ELKIN ◽  
Lauren WILLIAMS ◽  
Margaret MOORE ◽  
Margaret E. HODSON ◽  
Olga M. RUTHERFORD
Keyword(s):  
Bone Mineral Density ◽  
Skeletal Muscle ◽  
Cystic Fibrosis ◽  
Muscle Strength ◽  
Muscle Mass ◽  
Bone Mineral ◽  
Skeletal Muscle Mass ◽  
Mineral Density ◽  
Relationship Of

Musculoskeletal profile of amateur combat athletes: body composition, muscular strength and striking power

2021 ◽  
Author(s):  
Luke Del Vecchio ◽  
Nattai Borges ◽  
Campbell MacGregor ◽  
Jarrod D. Meerkin ◽  
Mike Climstein
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Lumbar Spine ◽  
Muscle Mass ◽  
Bone Mineral ◽  
Lower Limb ◽  
Mineral Density ◽  
Lean Muscle Mass ◽  
Total Body ◽  
Physiological Tests

Background: Previous research highlighted positive musculoskeletal adaptations resulting from mechanical forces and loadings distinctive to impacts and movements with sports participation. However, little is known about these adaptations in combat athletes. The aim of this study was to quantify bone mineral density, lean muscle mass and punching and kicking power in amateur male combat athletes. Methods: Thirteen male combat athletes (lightweight and middleweight) volunteered all physiological tests including dual energy X-ray absorptiometry for bone mineral density (BMD) segmental body composition (lean muscle mass, LMM), muscle strength and striking power, sedentary controls (n = 15) were used for selected DXA outcome variables. Results: There were significant differences (p < 0.05) between combat groups for lumbar spine (+5.0%), dominant arm (+4.4%) BMD, and dominant and non-dominant leg LMM (+21.8% and +22.6%). Controls had significantly (p < 0.05) high adiposity (+36.8% relative), visceral adipose tissue (VAT) mass (+69.7%), VAT area (+69.5%), lower total body BMD (−8.4%) and lumbar spine BMD (−13.8%) than controls. No differences in lower limb BMD were seen in combat groups. Arm lean mass differences (dominant versus non-dominant) were significantly different between combat groups (p < 0.05, 4.2% versus 7.3%). There were no differences in punch/kick power (absolute or relative) between combat groups. 5RM strength (bench and squat) correlated significantly with upper limb striking power (r = 0.57), dominant and non-dominant leg BMD (r = 0.67, r = 0.70, respectively) and total body BMD (r = 0.59). Conclusion: BMD and LMM appear to be particularly important to discriminate between dominant and non-dominant upper limbs and less so for lower limb dominance in recreational combat athletes.

scholarly journals Bone Mineral Density in Cystic Fibrosis Patients with the CFTR I1234V Mutation in a Large Kindred Family Is Associated with Pancreatic Sufficiency

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Atqah Abdul Wahab ◽  
M. Hammoudeh ◽  
Mona Allangawi ◽  
Fawziya Al-Khalaf ◽  
Prem Chandra
Keyword(s):  
Bone Mineral Density ◽  
Cystic Fibrosis ◽  
Lumbar Spine ◽  
Bone Mineral ◽  
Whole Body ◽  
Mineral Density ◽  
Total Hip ◽  
Radiographic Absorptiometry ◽  
The Mean ◽  
Total Body

Objectives. To study bone mineral density (BMD) in cystic fibrosis (CF) children and adults with the CFTR I1234V mutation associated with pancreatic sufficiency.Methods. Lumbar spine, total hip, and whole-body mineral density were measured by dual-energy radiographic absorptiometry (DEXA) scan.Zscore was used for those less than 21 years andTscore was used for those 21 years or older.Results. Twenty-one CF patients were younger than 21 years and 5 CF patients were 21 years or older. Mean age was 17.29 ± 4.95 years, ranging from 10 to 33 years. The mean BMDZscores for patients younger than 21 years were −0.69 ± 0.96 (lumbar spine = L1–L4), −0.48 ± 0.92 (total hip), and −0.38 ± 0.86 (total body). The meanTscores for patients 21 years or older were 0.14 ± 0.7 (L1–L4), 0.38 ± 1 (total hip), and 0.52 ± 1.03 (total body). BMD reduction less than −1 was found in 7 (26.9%) CF patients. Vitamin D deficiency in 20 CF patients (76.9%) tended to be lower in CF patients with low BMD. BMD was significantly correlated with FEV1; however, no significant association was observed withP. aeruginosacolonization.Conclusion. BMD reduction does occur in patients with mild CFTR mutation associated with pancreatic sufficiency.

scholarly journals Correlation of Muscle Strength and Mass with Bone Mineral Density in Postmenopausal Women

2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Veline Martínez ◽  
Harold Saavedra ◽  
Mayra Rojas ◽  
Juan José Martínez ◽  
Marisol Posada ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Muscle Strength ◽  
Muscle Mass ◽  
Bone Mineral ◽  
Systemic Disease ◽  
Fragility Fractures ◽  
Correlation Study ◽  
Mineral Density ◽  
Health Studies ◽  
Index Weight

Introduction: Osteoporosis is a systemic disease of the bone, which entails an increased riskof fracture, with high impact on morbidity, mortality and costs in the health system. Severalstudies have shown a relationship between muscle mass and strength with bone mineral density.Our objective is to determine the correlation between these variables in postmenopausalwomen. Materials and Methods: For the correlation study, 100 postmenopausal womenolder than 50 years were selected randomly and a sociodemographic survey was conducted,and muscle strength was determined by manual grip strength, which was measured with adigital dynamometer. Bone mineral density measurements and muscle mass were obtainedwith densitometry. The correlation between strength, muscle mass, and bone mineral densitywas determined by a Spearman correlation. Results: The average age was 62.8 ± 7.48. Femurand column bone mineral density were significantly related to the muscle mass index, weight,and body mass index. The prevalence of fragility fracture was 17%. The bone mineral densityof the femur was lower in patients with fragile fracture, and there was a negative and significantcorrelation between femur bone mineral density and skeletal muscle mass index. Conclusion:Bone health studies should include the study of muscle mass index and the skeletal musclemass index. The improvement of the muscle mass index can influence femoral and vertebralbone mineral density with significant impact on fragility fractures. This is the first study of itskind conducted in Colombia and South America.

Bone Mineral Density, Body Composition, and Muscle Strength in Premenopausal Women with Mental Retardation

1998 ◽  
Vol 15 (4) ◽  
pp. 345-356
Author(s):  
Manny Felix ◽  
Jeff McCubbin ◽  
Janet Shaw
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Mental Retardation ◽  
Muscle Strength ◽  
Femoral Neck ◽  
Muscle Mass ◽  
Bone Mineral ◽  
Premenopausal Women ◽  
Whole Body ◽  
Mineral Density

Many women with mild to moderate mental retardation (MMR) exhibit low levels of physical activity, muscle strength, and muscle mass, which place these individuals at risk for osteoporosis. Bone mineral density (BMD), the primary index of osteoporosis, of the femoral neck and the whole body was measured in premenopausal women with (M age = 28.14 ± 8.43) and without (M age = 29.64 ± 10.86) mental retardation (MMR and NMR, respectively). Multivariate analyses revealed no differences (p > .05) between groups (MMR = 16, NMR = 16) for BMD values. Significant differences existed (p < .05) between groups on body composition and muscle strength variables. In the MMR group, significant positive relationships (p < .05) were found between lean muscle mass and both femoral neck (r = .74) and whole body (r = .81) BMD. Unaccounted lifestyle factors may have contributed to nonsignificant BMD values between groups.

The effects of whole body vibration therapy on bone mineral density and leg muscle strength in older adults: a systematic review and meta-analysis

2011 ◽  
Vol 25 (11) ◽  
pp. 975-988 ◽  
Author(s):  
Ricky WK Lau ◽  
Lin-Rong Liao ◽  
Felix Yu ◽  
Tilda Teo ◽  
Raymond CK Chung ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Older Adults ◽  
Muscle Strength ◽  
Bone Mineral ◽  
Whole Body Vibration ◽  
Whole Body ◽  
Mineral Density ◽  
Body Vibration ◽  
Leg Muscle ◽  
Standardized Mean Difference

Objective: A systematic review and meta-analysis of randomized controlled trials was undertaken to determine whether whole body vibration improves bone mineral density and leg muscle strength in older adults. Data sources: Sources included MEDLINE, CINAHL, EMBASE, PEDro, PubMed, Science Citation Index and the reference list of each eligible article. Review methods: Article search and selection was performed independently by two researchers. The methodological quality of each selected article was rated by the PEDro scale. Results: Thirteen randomized trials (18 articles) totalling 896 subjects fulfilled the selection criteria. Four were considered to have good or excellent methodological quality and the rest were rated as fair. Meta-analyses revealed that whole body vibration has no significant effect on hip or lumbar spine bone mineral density in older women when compared with no intervention or active exercise ( P > 0.05). Whole body vibration, however, had a significant treatment effect on knee extension dynamic strength (standardized mean difference = 0.63, P = 0.006), leg extension isometric strength (standardized mean difference = 0.57, P = 0.003), and functional measures of leg muscle strength such as jumping height (standardized mean difference = 0.51, P = 0.010) and performance in sit-to-stand (standardized mean difference = 0.72, P < 0.001) among older adults compared with no intervention. Conclusion: Whole body vibration is beneficial for enhancing leg muscle strength among older adults. However, the review suggests that whole body vibration has no overall treatment effect on bone mineral density in older women. No randomized trial has examined the effects of whole body vibration on bone mineral density in older men.

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