Muscle function during fatigue in myoadenylate deaminase-deficient Dutch subjects

2000 ◽  
Vol 98 (5) ◽  
pp. 579-585 ◽  
Author(s):  
C. J. DE RUITER ◽  
B. G. M. VAN ENGELEN ◽  
R. A. WEVERS ◽  
A. DE HAAN
Keyword(s):  
Muscle Function ◽  
Adductor Pollicis ◽  
Moderate Intensity ◽  
Force Output ◽  
Short Term ◽  
Shortening Velocity ◽  
Vigorous Exercise ◽  
Adductor Pollicis Muscle ◽  
Left Hand ◽  
Myoadenylate Deaminase

Myoadenylate deaminase (MAD) is an enzyme active in skeletal muscle, probably during exercise of moderate intensity but certainly during vigorous exercise, when the deamination of AMP leads to increased levels of IMP and ammonia. There is controversy about the clinical significance of MAD deficiency. The main objective of the present study was to investigate the extent to which genetically confirmed MAD deficiency affects muscle function under conditions of maximal short-term electrically induced activation. The left hand was immobilized and adductor pollicis muscle function was investigated. To exclude the influence of central factors, such as the patient's motivation, the ulnar nerve was maximally electrically activated and force output was measured at the thumb. Sixty rapid shortening contractions resulted in a decrease of maximal power to 34.2±5.4% and 33.3±6.3% (means±S.D.) of the values for unfatigued muscle in the control and MAD-deficient subjects respectively (P > 0.05; n = 7). Maximal isometric forces and shortening velocities did not differ between groups in unfatigued, fatigued or recovered muscle. None of the subjects experienced exercise-related muscle aches or cramps. In conclusion, MAD deficiency does not appear to affect adductor pollicis muscle force, shortening velocity and relaxation, either during or after maximal short-term activation.

scholarly journals Assessment of adductor pollicis muscle function in critically ill patients

Critical Care ◽  
10.1186/cc576 ◽  
1999 ◽  
Vol 3 (Suppl 1) ◽  
pp. P203
Author(s):  
ML Harris ◽  
YM Luo ◽  
SJ Clark ◽  
JA Wendon ◽  
J Moxham
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Muscle Function ◽  
Adductor Pollicis ◽  
Adductor Pollicis Muscle

Muscle function during repetitive moderate-intensity muscle contractions in myoadenylate deaminase-deficient Dutch subjects

2002 ◽  
Vol 102 (5) ◽  
pp. 531 ◽  
Author(s):  
C. J. de RUITER ◽  
A. M. MAY ◽  
B. G. M. van ENGELEN ◽  
R. A. WEVERS ◽  
G. C. STEENBERGEN-SPANJERS ◽  
...  
Keyword(s):  
Muscle Function ◽  
Muscle Contractions ◽  
Moderate Intensity ◽  
Myoadenylate Deaminase

scholarly journals 1845 ADDUCTOR POLLICIS MUSCLE FUNCTION TESTS IN CYSTIC FIBROSIS

1985 ◽  
Vol 19 (4) ◽  
pp. 418A-418A
Author(s):  
A Szeinberg ◽  
L Levy ◽  
I M Eraser ◽  
C Mindorff ◽  
H Levison
Keyword(s):  
Cystic Fibrosis ◽  
Muscle Function ◽  
Adductor Pollicis ◽  
Adductor Pollicis Muscle ◽  
Function Tests

scholarly journals Long-Term Microgravity Effects on Isometric Handgrip and Precision Pinch Force with Visual and Proprioceptive Feedback

2018 ◽  
Vol 2018 ◽  
pp. 1-11
Author(s):  
Ilario Puglia ◽  
Michele Balsamo ◽  
Marco Vukich ◽  
Valfredo Zolesi
Keyword(s):  
Maximum Voluntary Contraction ◽  
Space Station ◽  
Voluntary Contraction ◽  
Force Output ◽  
Isometric Handgrip ◽  
Short Term ◽  
Space Flights ◽  
Pinch Force ◽  
Long Duration

The study and analysis of human physiology during short- and long-duration space flights are the most valuable approach in order to evaluate the effect of microgravity on the human body and to develop possible countermeasures in prevision of future exploratory missions and Mars expeditions. Hand performances such as force output and manipulation capacity are fundamental for astronauts’ intra- and extravehicular activities. Previous studies on upper limb conducted on astronauts during short-term missions (10 days) indicated a temporary partial reduction in the handgrip maximum voluntary contraction (MVC) followed by a prompt recovery and adaptation to weightlessness during the last days of the mission. In the present study, we report on the “Crew’s Health: Investigation on Reduced Operability” (CHIRO) protocol, developed for handgrip and pinch force investigations, performed during the six months increment 7 and increment 8 (2003-2004) onboard International Space Station (ISS). We found that handgrip and pinch force performance are reduced during long-term increments in space and are not followed by adaptation during the mission, as conversely reported during short-term increment experiments. The application of protocols developed in space will be eligible to astronauts during long-term space missions and to patients affected by muscle atrophy diseases or nervous system injury on Earth.

Slower fatigue and faster recovery of the adductor pollicis muscle in women matched for strength with men

1999 ◽  
Vol 167 (3) ◽  
pp. 233-239 ◽  
Author(s):  
Fulco ◽  
Rock ◽  
Muza ◽  
Lammi ◽  
Cymerman ◽  
...  
Keyword(s):  
Adductor Pollicis ◽  
Adductor Pollicis Muscle

Muscle function during jumping in frogs. I. Sarcomere length change, EMG pattern, and jumping performance

1996 ◽  
Vol 271 (2) ◽  
pp. C563-C570 ◽  
Author(s):  
G. J. Lutz ◽  
L. C. Rome
Keyword(s):  
Mechanical Properties ◽  
Muscle Function ◽  
Length Change ◽  
Operating Conditions ◽  
Mechanical Power ◽  
Shortening Velocity ◽  
Jumping Performance ◽  
Angular Velocities ◽  
High Level

We determined the influence of temperature on muscle function during jumping to better understand how the frog muscular system is designed to generate a high level of mechanical power. Maximal jumping performance and the in vivo operating conditions of the semimembranosus muscle (SM), a hip extensor, were measured and related to the mechanical properties of the isolated SM in the accompanying paper [Muscle function during jumping in frogs. II. Mechanical properties of muscle: implication for system design. Am. J. Physiol. 271 (Cell Physiol. 40): C571-C578, 1996]. Reducing temperature from 25 to 15 degrees C caused a 1.75-fold decline in peak mechanical power generation and a proportional decline in aerial jump distance. The hip and knee joint excursions were nearly the same at both temperatures. Accordingly, sarcomeres shortened over the same range (2.4 to 1.9 microns) at both temperatures, corresponding to myofilament overlap at least 90% of maximal. At the low temperature, however, movements were made more slowly. Angular velocities were 1.2- to 1.4-fold lower, and ground contact time was increased by 1.33-fold at 15 degrees C. Average shortening velocity of the SM was only 1.2-fold lower at 15 degrees C than at 25 degrees C. The low Q10 of velocity is in agreement with that predicted for muscles shortening against an inertial load.

scholarly journals ADDUCTOR POLLICIS MUSCLE THICKNESS AND PREDICTION OF POSTOPERATIVE MORTALITY IN PATIENTS WITH STOMACH CANCER

2018 ◽  
Vol 31 (1) ◽  
Author(s):  
Aline Kirjner POZIOMYCK ◽  
Oly Campos CORLETA ◽  
Leandro Totti CAVAZZOLA ◽  
Antonio Carlos WESTON ◽  
Edson Braga LAMEU ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Stomach Cancer ◽  
Nutritional Assessment ◽  
Postoperative Mortality ◽  
Muscle Thickness ◽  
Adductor Pollicis ◽  
Dominant Hand ◽  
Adductor Pollicis Muscle ◽  
Risk Of Death ◽  
Muscle Compartment

ABSTRACT Background: Malnutrition is very prevalent in patients with gastric cancer and increases the risk of morbidity and mortality. Adductor pollicis muscle thickness (APMT) appears as an important objective, quick, inexpensive and noninvasive measure to assess the muscle compartment Aim: To compare APMT and other nutritional assessment methods and to correlate these methods with postoperative mortality Methods: Forty-four patients, 29 men and 15 women, mean age of 63±10.2 and ranging from 34-83 years, who underwent nine (20.5%) partial and 34 (77.3%) total gastrectomies due to stomach cancer (stage II to IIIa) were preoperatively assessed by Patient Generated Subjective Global Assessment (PG-SGA), anthropometry and laboratorial profile Results: APMT better predicted death (p<0.001) on both, dominant and non-dominant hand, and well correlated with albumin (p=0.039) and PG-SGA (p=0.007) Conclusion: APMT clearly allowed to determine malnutrition and to predict risk of death in patients with gastric cancer.

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