Neuropeptide Y (Npy) Receptors and Responses in Isolated Cardiac Cells

1993 ◽  
Vol 85 (s29) ◽  
pp. 39P-39P
Author(s):  
BC Millar ◽  
BJ McDermott
Keyword(s):  
Neuropeptide Y ◽  
Cardiac Cells ◽  
Isolated Cardiac Cells ◽  
Npy Receptors

Electrophysiology of the Sodium-Potassium-ATPase in Cardiac Cells

2001 ◽  
Vol 81 (4) ◽  
pp. 1791-1826 ◽  
Author(s):  
Helfried Günther Glitsch
Keyword(s):  
Cell Membrane ◽  
Potential Gradient ◽  
Outward Current ◽  
Pump Current ◽  
Cardiac Cells ◽  
Animal Cells ◽  
Excitable Cells ◽  
Extracellular Medium ◽  
Enzymatic Isolation ◽  
Isolated Cardiac Cells

Like several other ion transporters, the Na+-K+ pump of animal cells is electrogenic. The pump generates the pump current I p. Under physiological conditions, I p is an outward current. It can be measured by electrophysiological methods. These methods permit the study of characteristics of the Na+-K+ pump in its physiological environment, i.e., in the cell membrane. The cell membrane, across which a potential gradient exists, separates the cytosol and extracellular medium, which have distinctly different ionic compositions. The introduction of the patch-clamp techniques and the enzymatic isolation of cells have facilitated the investigation of I p in single cardiac myocytes. This review summarizes and discusses the results obtained from I p measurements in isolated cardiac cells. These results offer new exciting insights into the voltage and ionic dependence of the Na+-K+ pump activity, its effect on membrane potential, and its modulation by hormones, transmitters, and drugs. They are fundamental for our current understanding of Na+-K+ pumping in electrically excitable cells.

Characterization of Neuropeptide Y ( NPY ) Receptors

1998 ◽  
Vol 1 (1) ◽  
Author(s):  
William Karbon ◽  
Julie Marasco ◽  
Clarence Hale
Keyword(s):  
Neuropeptide Y ◽  
Npy Receptors

Development of a linear transient model for stimulation of isolated cardiac cells

2000 ◽  
Vol 12 (3) ◽  
pp. 217-222 ◽  
Author(s):  
P. Pham ◽  
G. Cauffet ◽  
A. Bardou ◽  
J. Olivares ◽  
E. Novakov
Keyword(s):  
Cardiac Cells ◽  
Transient Model ◽  
Isolated Cardiac Cells ◽  
Stimulation Of
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