Effect of Ursodeoxycholic Acid (UDCA) on Hepatic Bile Acid Handling in Primary Biliary Cirrhosis (PBC)

1992 ◽  
Vol 82 (s26) ◽  
pp. 24P-25P
Author(s):  
R.P. Jazrawi ◽  
J. De Caestecker ◽  
P.M. Goggin ◽  
J.D. Maxwell ◽  
A. Brittain ◽  
...  
Keyword(s):  
Bile Acid ◽  
Primary Biliary Cirrhosis ◽  
Ursodeoxycholic Acid ◽  
Biliary Cirrhosis ◽  
Hepatic Bile

Hepatic bile acid handling in primary biliary cirrhosis: Effect of ursodeoxycholic acid

2000 ◽  
Vol 118 (4) ◽  
pp. A901
Author(s):  
Paolo Pazzi ◽  
Raffaella Scagliarini ◽  
Susanna Gamberini ◽  
Napoleone Prandini ◽  
Sergio Gullini ◽  
...  
Keyword(s):  
Bile Acid ◽  
Primary Biliary Cirrhosis ◽  
Ursodeoxycholic Acid ◽  
Biliary Cirrhosis ◽  
Hepatic Bile

Ursodeoxycholic acid administration on bile acid metabolism in patients with early stages of primary biliary cirrhosis

1993 ◽  
Vol 38 (5) ◽  
pp. 896-902 ◽  
Author(s):  
Giuseppe Mazzella ◽  
Paolo Parini ◽  
Franco Bazzoli ◽  
Nicola Villanova ◽  
Davide Festi ◽  
...  
Keyword(s):  
Bile Acid ◽  
Primary Biliary Cirrhosis ◽  
Ursodeoxycholic Acid ◽  
Acid Metabolism ◽  
Bile Acid Metabolism ◽  
Biliary Cirrhosis ◽  
Early Stages ◽  
Acid Administration

Effect of ursodeoxycholic acid on bile acid metabolism in primary biliary cirrhosis

Hepatology ◽  
1989 ◽  
Vol 10 (4) ◽  
pp. 414-419 ◽  
Author(s):  
Ashok K. Batta ◽  
Gerald Salen ◽  
Renu Arora ◽  
Sarah Shefer ◽  
G. Stephen Tint ◽  
...  
Keyword(s):  
Bile Acid ◽  
Primary Biliary Cirrhosis ◽  
Ursodeoxycholic Acid ◽  
Acid Metabolism ◽  
Bile Acid Metabolism ◽  
Biliary Cirrhosis

scholarly journals Urisodeoxycholic Acid in Treatment of Liver Cirrhosis

2021 ◽  
Vol 9 (9) ◽  
pp. 1869-1873
Author(s):  
Sangale Mukta
Keyword(s):  
Liver Cirrhosis ◽  
Bile Acid ◽  
Primary Biliary Cirrhosis ◽  
Ursodeoxycholic Acid ◽  
Primary Sclerosing Cholangitis ◽  
Liver Diseases ◽  
Sclerosing Cholangitis ◽  
Chronic Liver ◽  
Biliary Cirrhosis ◽  
Chronic Liver Diseases

Abstract: Ursodeoxycholic acid is a dihy- droxy bile acid with a rapidly expanding spectrum of usage in acute and chronic liver diseases. The various mechanisms of action of this hydrophilic bile acid include direct cytoprotection, detergent action on dysfunctional microtubules, immunomodulation and induction of hypercholer- esis. Its efficacy in primary biliary cirrhosis and primary sclerosing cholangitis as an adjunct to medical therapy has been well established.Ursodeoxycholic acid prolongs survival in primary biliary cirrhosis and it improves biochemical parameters of cholestasis in various other cholestatic disorders including primary sclerosing cholangitis, intrahepatic cholestasis of pregnancy, cystic fibrosis and total parenteral nutritioninduced cholestasis. However, a positive effect on survival remains to be established in these diseases. Ursodeoxycholic acid is of unproven efficacy in non- cholestatic disorders such as acute rejection after liver transplantation, non-alcoholic steatohepatitis, alcoholic liver disease and chronic viral hepatitis. This review outlines the present knowledge of the Pharmacology of ursodeoxycholic acid, and presents data from clinical trials on its use in chronic liver diseases. Keywords: Liver cirrhosis, Urisodeoxycholic acid

Corrigendum to: “Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health” [J Hepatol 2012;57:133–140]

2014 ◽  
Vol 60 (3) ◽  
pp. 684
Author(s):  
Karin Dilger ◽  
Simon Hohenester ◽  
Ursula Winkler-Budenhofer ◽  
Barbara A.J. Bastiaansen ◽  
Frank G. Schaap ◽  
...  
Keyword(s):  
Bile Acid ◽  
Primary Biliary Cirrhosis ◽  
Ursodeoxycholic Acid ◽  
Biliary Cirrhosis ◽  
Bile Acid Profiles

Defects in hepatic bile acid handling in chronic C hepatitis and in primary biliary cirrhosis

1999 ◽  
Vol 20 (5) ◽  
pp. 490
Author(s):  
N. Prandini ◽  
P. Pazzi ◽  
R. Scagliarini ◽  
S. Gamberini ◽  
R. P. Jazrawi ◽  
...  
Keyword(s):  
Bile Acid ◽  
Primary Biliary Cirrhosis ◽  
Biliary Cirrhosis ◽  
Hepatic Bile

Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health

2012 ◽  
Vol 57 (1) ◽  
pp. 133-140 ◽  
Author(s):  
Karin Dilger ◽  
Simon Hohenester ◽  
Ursula Winkler-Budenhofer ◽  
Barbara A.J. Bastiaansen ◽  
Frank G. Schaap ◽  
...  
Keyword(s):  
Bile Acid ◽  
Primary Biliary Cirrhosis ◽  
Ursodeoxycholic Acid ◽  
Biliary Cirrhosis ◽  
Bile Acid Profiles

Changes in bile acid composition in patients with primary biliary cirrhosis induced by ursodeoxycholic acid administration

Hepatology ◽  
1991 ◽  
Vol 14 (6) ◽  
pp. 1000-1007 ◽  
Author(s):  
Andrea Crosignani ◽  
Mauro Podda ◽  
Pier Maria Battezzati ◽  
Emanuela Bertolini ◽  
Massimo Zuin ◽  
...  
Keyword(s):  
Bile Acid ◽  
Primary Biliary Cirrhosis ◽  
Ursodeoxycholic Acid ◽  
Acid Composition ◽  
Biliary Cirrhosis ◽  
Acid Administration
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