The Effect of Dibutyryl-Cyclic Amp on the Ciliary Activity of Respiratory Epithelium from Patients with Cystic Fibrosis G DI Benedetto

1990 ◽  
Vol 78 (s22) ◽  
pp. 2P-3P
Author(s):  
G D Benedetto ◽  
A Mehta ◽  
FS Manara-Shediac
Keyword(s):  
Cystic Fibrosis ◽  
Cyclic Amp ◽  
Respiratory Epithelium ◽  
Ciliary Activity ◽  
Dibutyryl Cyclic Amp

The inhibitory effects of some adenosine nucleolipids on the lipolysis in rat epididymal fat pads in vitro

1979 ◽  
Vol 44 (5) ◽  
pp. 1651-1656 ◽  
Author(s):  
Sixtus Hynie ◽  
Jiří Smrt
Keyword(s):  
Fatty Acids ◽  
Cyclic Amp ◽  
Dibutyryl Cyclic Amp ◽  
Inhibitory Effects ◽  
Epididymal Fat ◽  
Fat Pads

3'-Oleolyl-2,3-dihydroxypropyl-AMP, 3'-stearoyl-2,3-dihydroxypropyl-AMP, octadecyl-AMP and palmitamidoethyl-AMP inhibited in comparison with adenosine or fatty acids much stronger the lipolysis in rat epididymal fat pads in vitro stimulated by isoproterenol, theophylline and dibutyryl cyclic AMP. The inhibition of the effects of the two latter drugs suggest that the described effect is caused not only by the inhibition of the cyclic AMP production but also by the inhibition of its effect on the following steps in process of lipolysis.

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