Central Deposition of Aerosols as a Detemining Factor in Bronchial Responsiveness

1986 ◽  
Vol 71 (s15) ◽  
pp. 82P-82P
Author(s):  
M K Gillett ◽  
B A Briggs ◽  
P D Snashall
Keyword(s):  
Bronchial Responsiveness

Comparison of 4 AM and 4 PM Bronchial Responsiveness to Hypertonic Saline in Asthma

Lung ◽  
2006 ◽  
Vol 184 (6) ◽  
pp. 341-346 ◽  
Author(s):  
Erica Ferraz ◽  
Marcos C. Borges ◽  
J. Terra-Filho ◽  
José A. B. Martinez ◽  
Elcio O. Vianna
Keyword(s):  
Hypertonic Saline ◽  
Bronchial Responsiveness

Serum Eosinophil Cationic Protein and Bronchial Responsiveness in Pediatric and Adolescent Asthma Patients

CHEST Journal ◽  
1999 ◽  
Vol 116 (2) ◽  
pp. 301-305 ◽  
Author(s):  
Wilfried Gruber ◽  
Ernst Eber ◽  
Andreas Pfleger ◽  
Manfred Modl ◽  
Ingrid Meister ◽  
...  
Keyword(s):  
Eosinophil Cationic Protein ◽  
Cationic Protein ◽  
Bronchial Responsiveness ◽  
Asthma Patients

Bronchial Responsiveness to Eucapnic Hyperventilation and Methacholine Following Exposure to Organic Dust

CHEST Journal ◽  
2002 ◽  
Vol 122 (1) ◽  
pp. 363-368 ◽  
Author(s):  
Britt-Marie Sundblad ◽  
Lena Palmberg ◽  
Kjell Larsson
Keyword(s):  
Organic Dust ◽  
Bronchial Responsiveness

Lack of interaction of hyperpnoea with methacholine and histamine in asthma

1998 ◽  
Vol 95 (5) ◽  
pp. 611-619 ◽  
Author(s):  
Suree SOMPRADEEKUL ◽  
Rana HEJAL ◽  
Melissa McLANE ◽  
K. A. LENNER ◽  
J. A. NELSON ◽  
...  
Keyword(s):  
Blood Flow ◽  
Forced Expiratory Volume ◽  
Additive Effects ◽  
Positive Interaction ◽  
Bronchial Responsiveness ◽  
Individual Effects ◽  
The Individual ◽  
Airway Calibre ◽  
Effector Mechanisms

1.The thermal precipitants of asthma (exercise and hyperventilation) appear to have a unique pathogenesis that does not alter bronchial responsiveness. In the present work, we tested whether hyperpnoea interacts with other constrictor stimuli. 2.To provide data on this issue, we exposed 17 subjects with asthma to isocapnic hyperventilation of frigid air (HV), methacholine (METH) and histamine (HIS) alone and in combination. 3.With HV (mean ventilation = 55.6±7.7 litres/min), METH (2.20±0.7 ;mmol/l) and HIS (10.35±5.04 ;mmol/l) alone, the decrements in forced expiratory volume in 1 ;s (FEV1) from baseline were 27.4±3.4, 27.4±3.8 and 32.4±3% respectively (n = 9). Giving the agonists simultaneously did not produce additive effects (ΔFEV1 HV+METH = 32.8±3.6%; HV+HIS = 28.7±5.1%). None of the individual or combined responses was significantly different from each other. Changing the sequence of the experiments and giving METH at the height of the HV-induced bronchial narrowing, instead of during hyperpnoea, did not alter the findings (n = 8). The maximum fall in FEV1 after both bronchoconstrictors in this experiment (ΔFEV1 = 32.3±4.3%) was not significantly different from either alone (HV = 22.8±1.0%; METH = 27.3±1.9%). When METH and HIS were administered together, however (n = 5), a positive interaction ensued (METH = 1.53±0.56 ;mmol/l, ΔFEV1 = 15.6±4.6%; HIS = 4.77±2.07 ;mmol/l, ΔFEV1 = 18.8±3.1%; METH+HIS ΔFEV1 = 33.4±5.2%; P< 0.001 compared with the individual effects). 4.These results indicate that HV does not interact with stimuli that directly or indirectly modulate airway calibre. It is unclear if this effect represents protection conferred from increased bronchial blood flow or derives from differences in effector mechanisms between the thermal and pharmacological agonists.

Effect of Betaxolol on Bronchial Responsiveness in Mild Asthmatic Subjects with Chronic Glaucoma: A Pilot Study

1992 ◽  
pp. 279-284
Author(s):  
Alfredo Chetta ◽  
Stefano A. Gandolfi ◽  
Antonio Foresi ◽  
Mario Del Donno ◽  
Daniela Moretti ◽  
...  
Keyword(s):  
Pilot Study ◽  
Bronchial Responsiveness ◽  
Chronic Glaucoma ◽  
Mild Asthmatic

scholarly journals Perspective of Bronchial Responsiveness According to an Inhaled Anti-inflammatory Treatment in Cough Asthma

1998 ◽  
Vol 45 (5) ◽  
pp. 1012
Author(s):  
Seung Hyug Moon ◽  
Shin Young Ki ◽  
Yong Hoon Kim ◽  
Choon Sik Park
Keyword(s):  
Bronchial Responsiveness ◽  
Anti Inflammatory
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