Relationship of the sympathetic nervous system to upper motor neurone lesions and the bladder

1986 ◽  
Vol 70 (S14) ◽  
pp. 57s-58s
Author(s):  
David G. Thomas
1957 ◽  
Vol 35 (1) ◽  
pp. 983-992
Author(s):  
R. A. Cleghorn ◽  
J. L. A. Fowler

Five male dogs were adrenalectomized and sympathectomized and maintained by adrenocortical extract for periods of weeks to months. Their general behavior did not differ from those subject to adrenalectomy alone, but in three it was observed that the hair grew long and curly. In the other two a lesser change may have been missed. Following withdrawal of the hormone, death occurred rather suddenly in three, and adrenal insufficiency developed sooner in the other two than in dogs only adrenalectomized. Pathological changes in the gastrointestinal tract were qualitatively the same following death after hormone withdrawal in the adrenalectomized–sympathectomized animals and in dogs only adrenalectomized. Blood changes appeared to be no different in the two groups. The urinary changes with respect to water and electrolytes differed in that the sympathectomized group appeared to take in less water and excrete less urine, but to put out more sodium and chloride, in the few days following withdrawal of hormone. These findings are discussed in particular with respect to the relationship of adrenergic function of the sympathetic nervous system and hormones of the adrenal cortex.


1957 ◽  
Vol 35 (11) ◽  
pp. 983-992
Author(s):  
R. A. Cleghorn ◽  
J. L. A. Fowler

Five male dogs were adrenalectomized and sympathectomized and maintained by adrenocortical extract for periods of weeks to months. Their general behavior did not differ from those subject to adrenalectomy alone, but in three it was observed that the hair grew long and curly. In the other two a lesser change may have been missed. Following withdrawal of the hormone, death occurred rather suddenly in three, and adrenal insufficiency developed sooner in the other two than in dogs only adrenalectomized. Pathological changes in the gastrointestinal tract were qualitatively the same following death after hormone withdrawal in the adrenalectomized–sympathectomized animals and in dogs only adrenalectomized. Blood changes appeared to be no different in the two groups. The urinary changes with respect to water and electrolytes differed in that the sympathectomized group appeared to take in less water and excrete less urine, but to put out more sodium and chloride, in the few days following withdrawal of hormone. These findings are discussed in particular with respect to the relationship of adrenergic function of the sympathetic nervous system and hormones of the adrenal cortex.


2020 ◽  
Vol VI (4) ◽  
pp. 213-214
Author(s):  
B. I. Vorotynskiy

Physiology has not yet given us positive data on the function of the sympathetic nervous system. Only recently, histologists have been able to prove that the nerve cells located in large sympathetic nodes do not differ in their morphological properties from cells of the central nervous system. This gives the right to assume that in the sympathetic nodes there are independent centers that are in the same dependence on the higher centers, as, for example, the centers of the spinal cord from the brain. We have very little data on the relationship of the sympathetic nervous system to the innervations of the bladder. On this basis, the author began to study this issue in the physiological laboratory of prof. Pavlova at the M. Academy.


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