Intra-individual variability in postural blood pressure in the elderly

1985 ◽  
Vol 69 (3) ◽  
pp. 337-341 ◽  
Author(s):  
Lewis A. Lipsitz ◽  
Helene A. Storch ◽  
Kenneth L. Minaker ◽  
John W. Rowe
Keyword(s):  
Blood Pressure ◽  
Body Weight ◽  
Systolic Blood Pressure ◽  
Orthostatic Hypotension ◽  
Coefficient Of Variation ◽  
Pressure Change ◽  
The Elderly ◽  
Blood Pressure Change ◽  
Blood Pressure Elevation ◽  
Basal Blood Pressure

1. Orthostatic hypotension, an age-related phenomenon, has been associated with hypertension and body weight variability. To evaluate the relative contributions of blood pressure elevation and abnormalities in extracellular volume regulation to orthostatic hypotension, elderly institutionalized subjects (mean age = 87 ± 7 years), taking no cardiovascular medications, underwent measurement of body weight (n = 15) and first morning supine and standing blood pressures (n = 19), 12–13 times per subject over a 2–4 week period. 2. There was a wide day-to-day variability in postural systolic blood pressure change (coefficient of variation = 533%) and a strong negative correlation between each day's postural change in systolic blood pressure and basal supine blood pressure (r = −0.55, P < 0.0001). 3. There was no association between postural blood pressure change and heart rate response or body weight changes, which were very small over the duration of the study (coefficient of variation = 0.6%). 4. Elderly individuals have intact homoeostatic mechanisms for the control of standing pressure when basal blood pressure is normal. Postural hypotension in the elderly is a variable phenomenon related to elevations in basal blood pressure.

Effect of time standing up on orthostatic blood pressure change in the elderly: The J-SHIPP Study

2005 ◽  
Vol 5 (4) ◽  
pp. 254-258 ◽  
Author(s):  
Yasuharu Tabara ◽  
Katsuhiko Kohara ◽  
Toshie Azechi ◽  
Michie Ohnishi ◽  
Shouzoh Ueki ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pressure Change ◽  
The Elderly ◽  
Blood Pressure Change ◽  
Orthostatic Blood Pressure ◽  
Standing Up

The characteristics of the postural blood pressure change in the elderly: A study at a CGA clinic

2007 ◽  
Vol 135 (1-2) ◽  
pp. 105
Author(s):  
Takashi Yamanaka ◽  
Emiko Takasugi ◽  
Norihiro Hotta ◽  
Sachiko Oinuma ◽  
Yutaka Kubo ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pressure Change ◽  
The Elderly ◽  
Blood Pressure Change

Fibrinogen synthesis stimulation by prostaglandin E1 and some other vasodilators

1977 ◽  
Vol 233 (1) ◽  
pp. H1-H19
Author(s):  
T. H. Carlson ◽  
D. C. Fradl ◽  
B. D. Leonard ◽  
S. H. Wentland ◽  
E. B. Reeve
Keyword(s):  
Blood Pressure ◽  
Cyclic Amp ◽  
Systolic Blood Pressure ◽  
Intravenous Infusion ◽  
Prostaglandin E1 ◽  
Pressure Change ◽  
Plasma Fibrinogen ◽  
Blood Pressure Change ◽  
Regression Equations ◽  
Arterial Blood

Three-hour constant-rate intravenous infusion into rabbits of 1-3 mg prostaglandin E1 (PGE1) per kilogram markedly increased plasma fibrinogen 24 h later. 131I-labeled fibrinogen and model studies showed increased synthesis underlay this. Similar PGE1 doses lowered systolic blood pressure. Maintaining systolic blood pressure by infusing noradrenaline with the PGE1 did not alter plasma fibrinogen response to PGE1; plasma fibrinogen was unchanged by noradrenaline infusion. Regression equations relating plasma fibrinogen increment to PGE1 dose, plasma fibrinogen increment to dose and systolic blood pressure change, and systolic blood pressure change to dose are given as well as the constants relating plasma fibrinogen increment to dose using the Michaelis-Menten equation. Infusions of cyclic AMP, dibutyryl cyclic AMP, and cyclic GMP intravenously led to only small plasma fibrinogen increases. Daily intravenous infusions of PGE1 led to loss of both plasma fibrinogen and systolic blood pressure responses in two animals; a third animal showed only loss of the former and a fourth only loss of the latter response. PGE1 slightly enhanced the small plasma fibrinogen increase following intravenous bradykinin. Approximate arterial blood PGE1 concentrations resulting from the intravenous infusion of 1 mg mg PGE1 kg-1 3 h-1 are calculated. These are compared with measured values.

scholarly journals Genome-wide association of trajectories of systolic blood pressure change

2016 ◽  
Vol 10 (S7) ◽  
Author(s):  
Anne E. Justice ◽  
Annie Green Howard ◽  
Geetha Chittoor ◽  
Lindsay Fernandez-Rhodes ◽  
Misa Graff ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Pressure Change ◽  
Genome Wide Association ◽  
Blood Pressure Change ◽  
Genome Wide

scholarly journals HYPNOTHERAPY DECREASES STRESS IN ELDERLY HYPERTENSION

2017 ◽  
Vol 1 (1) ◽  
pp. 1-10
Author(s):  
Kastubi Kastubi ◽  
Minarti Minarti ◽  
Noer Saudah
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Care Center ◽  
Intervention Group ◽  
Sampling Technique ◽  
Pressure Change ◽  
The Elderly ◽  
Control Group ◽  
Health Care Center ◽  
Elderly Hypertensive

Stress stimulates the sympathetic nervous encouraging the heart and cause an increasing blood pressure. Efforts to reduce hypertension pharmacological and non-pharmacological. Non-pharmacological experiment of which is hypnosis. The research objective was to analyze the decrease of stress to elderly hypertensive therapy with hypnotherapy. The research design used experimental pretest - Posttest with Control Group. The population were all the elderly with hypertension in the elderly health care center PacarKeling , and Kemayoran Surabaya with 35 elderlies. Number of sample 15 intervention group, 15 control group. The sampling technique used Simple Random Sampling. Variable intervention was therapeutic applications of hypnosis to elderly hypertensive. The dependent variable was the stress in elderly hypertensive. The statistical test used paired t-test. It showed changes in stress to the control group -7.33, while the experminent group amounted to 14.60. Results can reduce stress in the group treated with hypnotherapy an average decrease of 14.6. Results showed that there were differences in the level of stress control and experiment groups with significant value of p = 0.000 (p <0.05), The effect of hypnotherapy was also shown in the systolic blood pressure change between control and experiment groups showed a mean difference of ranks. In the control group 20.8, while in the experimental group 10.2. Mann Whitney test results obtained by the significant value of p = 0.000 (p <0.05) in mean systolic blood pressure differences between control and experiment groups. Hypnotherapy can reduce stress and blood pressure in the experiment group. Causes of stress on the individual such as physical pain, and the outside factor could be due to family problems, economic. Suggestions that hypnosis can be used as a new experiment method stress problem in the elderly

Isolated Systolic Blood Pressure Elevation in the Elderly

1989 ◽  
Vol 14 ◽  
pp. S14-20
Author(s):  
A. Amery ◽  
R. Fagard ◽  
J. Staessen ◽  
L. Thijs ◽  
R. van Hoof
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
The Elderly ◽  
Blood Pressure Elevation ◽  
Pressure Elevation

scholarly journals HYPNOTHERAPY DECREASES STRESS IN ELDERLY HYPERTENSION

2017 ◽  
Vol 1 (1) ◽  
pp. 1-10
Author(s):  
Kastubi Kastubi ◽  
Minarti Minarti ◽  
Noer Saudah
Keyword(s):  
Blood Pressure ◽  
Systolic Blood Pressure ◽  
Care Center ◽  
Intervention Group ◽  
Sampling Technique ◽  
Pressure Change ◽  
The Elderly ◽  
Control Group ◽  
Health Care Center ◽  
Elderly Hypertensive

Stress stimulates the sympathetic nervous encouraging the heart and cause an increasing blood pressure. Efforts to reduce hypertension pharmacological and non-pharmacological. Non-pharmacological experiment of which is hypnosis. The research objective was to analyze the decrease of stress to elderly hypertensive therapy with hypnotherapy. The research design used experimental pretest - Posttest with Control Group. The population were all the elderly with hypertension in the elderly health care center PacarKeling , and Kemayoran Surabaya with 35 elderlies. Number of sample 15 intervention group, 15 control group. The sampling technique used Simple Random Sampling. Variable intervention was therapeutic applications of hypnosis to elderly hypertensive. The dependent variable was the stress in elderly hypertensive. The statistical test used paired t-test. It showed changes in stress to the control group -7.33, while the experminent group amounted to 14.60. Results can reduce stress in the group treated with hypnotherapy an average decrease of 14.6. Results showed that there were differences in the level of stress control and experiment groups with significant value of p = 0.000 (p <0.05), The effect of hypnotherapy was also shown in the systolic blood pressure change between control and experiment groups showed a mean difference of ranks. In the control group 20.8, while in the experimental group 10.2. Mann Whitney test results obtained by the significant value of p = 0.000 (p <0.05) in mean systolic blood pressure differences between control and experiment groups. Hypnotherapy can reduce stress and blood pressure in the experiment group. Causes of stress on the individual such as physical pain, and the outside factor could be due to family problems, economic. Suggestions that hypnosis can be used as a new experiment method stress problem in the elderly

Abstract 10245: Arterial Stiffness, Central Pulsatile Hemodynamic Load and Orthostatic Hypotension: A Cross-sectional Survey of Community Residents in Chengdu

Circulation ◽  
2015 ◽  
Vol 132 (suppl_3) ◽  
Author(s):  
Kai Liu ◽  
Xiaoping Chen ◽  
Si Wang ◽  
Shixi Wan ◽  
Yufei Zhou ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Stiffness ◽  
Systolic Blood Pressure ◽  
Orthostatic Hypotension ◽  
Multiple Logistic Regression Analysis ◽  
The Elderly ◽  
Discriminatory Power ◽  
Receiver Operating Curve ◽  
Cross Sectional Survey ◽  
Central Systolic Blood Pressure

Introduction: Orthostatic hypotension (OH) is an independent risk factor for cardiovascular morbidity and often unrecognized in the elderly. The association between measures of central pulsatile hemodynamic load or arterial stiffness with OH is unclear. This study evaluated the usefulness of these indexes to identify OH. Hypothesis: We hypothesize that direct measures of central pulsatile hemodynamic load (e.g. central systolic blood pressure) and arterial stiffness (pulse wave velocity) both associated with OH. And Measures of central pulsatile hemodynamic load may represent a better indicator of OH. Methods: A sample of 1099 participants was recruited from the general population who attended health check-ups. Questionnaire, physical examination and laboratory tests were performance by a standard protocol. To assess the correlation between central hemodynamic indexes and the probability of OH, multiple logistic regression analysis was used to estimate the odds ratio in different models, and the discriminatory power of hemodynamic indexes for OH was assessed by the area under the receiver operating curve (ROC). Results: The prevalence of OH in this population was 5.6 %. Compared with those without OH, OH subjects had a higher age, SBP in sitting position, BP in supine position, brachial-ankle PWV (BaPWV) and central systolic blood pressure (CSBP) (all P<0.05). After adjusting for potential confounders, both CSBP (OR=1.039, 95%CI: 1.016-1.062, P=0.001) and BaPWV (OR=1.259, 95%CI: 1.130-1.402, P< 0.001) were significantly positive correlated with OH. However, in subgroup analysis, CSBP (OR=1.017, 95%CI: 0.985-1.050, P=0.310) was insignificantly associated with OH in non hypertension subgroup. In addition, BaPWV seemed to be a better discriminatory power than CSBP in both two subgroups (BaPWVAUC-CSBPAUC =0.127, 95%CI: 0.020-0.233, P=0.02 in non hypertension group; BaPWVAUC-CSBPAUC =0.118, 95%CI: -0.030-0.267, P=0.117 in hypertension group). Conclusion: BaPWV appears to be a better indicator of OH in the elderly. If a patient’s BaPWV is greater than 18m/s, Clinicians should better to carry out supine to standing blood pressures measurement in routine clinical practice.

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