Forearm Arterial Compliance: The Validation of a Plethysmographic Technique for the Measurement of Arterial Compliance

1984 ◽  
Vol 67 (1) ◽  
pp. 69-72 ◽  
Author(s):  
D. Fitchett ◽  
J. D. Bouthier ◽  
A. Ch. Simon ◽  
J. A. Levenson ◽  
M. E. Safar

1. Arterial compliance was determined in eight normal subjects and 23 patients with hypertension and vascular disease by two independent techniques: (a) with a plethysmographic strain gauge (to measure pulsatile forearm volume changes as representing intra-arterial volume changes) and an automated sphygmomanometric system (to measure pulse pressure) and (b) calculation from the local pulse wave velocity and dimension of the brachial artery measured by pulsed wave Doppler ultrasound. 2. Arterial compliance measured both by the plethysmographic technique and calculated from the pulse wave velocity was reduced in subjects with hypertension and vascular disease as compared with normal subjects. 3. The regression equation between the compliance determined by the plethysmographic technique (x) and that calculated (y) from the pulse wave velocity and brachial arterial diameter was y = 3.35x + 1.53, r = 0.77, P < 0.001. The good correlation appears to validate the plethysmographic technique as a method of determining arterial compliance.

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
F Antonini-Canterin ◽  
A Pepe ◽  
M Strazzanti ◽  
D Rivaben ◽  
E Nicolosi ◽  
...  

Abstract Background Guidelines recommend increased aortic stiffness as a negative prognostic factor to be considered in primary and secondary prevention. Pulse wave velocity (PWV) is a frequently employed surrogate marker of aortic stiffness. Carotid-femoral PWV is the most common index in research and clinical practice, but recently several velocity-encoded magnetic resonance imaging (MRI) techniques have been used for the evaluation of regional aortic arch PWV, where the stiffness seems to be particularly relevant from a prognostic point of view. Purposes. We developed a new ultrasound method for the assessment of aortic arch PWV, using a single-beat dual-gate simultaneous pulsed wave Doppler tracing. The aim of the study is to evaluate the feasibility of this new technique in a group of healthy volunteers. Methods We examined 126 healthy volunteers (81 females, 45 males, mean age 42 + 15 years, range 13-83 years) using a commercially available machine equipped with simultaneous dual-gate pulsed Doppler. Using the suprasternal approach, the first sample volume was placed in ascending aorta and the second one in descending aorta. The distance between the two sites was directly measured with a curvilinear tracing in the middle of the vessel, following the shape of the aortic arch. PWV was calculated as the ratio of distance (in millimiters) and the transit time (in milliseconds) measured using the "foot-to-foot" method. The results are then easily transformed, simplifying in the commonly unit of meters/second. Results Feasibility was 99%; in one case it was not possible to measure accurately the aortic arch PWV due to unfavorable suprasternal acustic window. The procedure time was very fast, requiring 2 + 1 minutes. Intraobserver and interobserver variability were 7% and 9% respectively. Aortic arch PWV, as expected, showed a strong correlation with age in males as well as in females (r= 0.71 and r = 0.60 respectively, p &lt; 0.001 for both); there was also a significant correlation with body mass index (r = 0.31; p &lt; 0.001). Aortic arch PWV values ranged from 3.1 to 8.5 m/s, showing a substantial overlap with normal values reported in MRI studies. Conclusions The direct measurement of aortic arch PWV is feasible and reproducible with ultrasound, using the novel single-beat dual-gate simultaneous pulsed wave Doppler tracing. This technique could be implemented in a standard echo examination, that is much more available than MRI studies. Further studies are needed to evaluate if Doppler-derived aortic arch PWV could provide additional prognostic information. Abstract P1830 Figure. Aortic Arch PWV


1998 ◽  
Vol 274 (4) ◽  
pp. H1393-H1403 ◽  
Author(s):  
Christopher M. Quick ◽  
David S. Berger ◽  
Abraham Noordergraaf

Recently, there has been renewed interest in estimating total arterial compliance. Because it cannot be measured directly, a lumped model is usually applied to derive compliance from aortic pressure and flow. The archetypical model, the classical two-element windkessel, assumes 1) system linearity and 2) infinite pulse wave velocity. To generalize this model, investigators have added more elements and have incorporated nonlinearities. A different approach is taken here. It is assumed that the arterial system 1) is linear and 2) has finite pulse wave velocity. In doing so, the windkessel is generalized by describing compliance as a complex function of frequency that relates input pressure to volume stored. By applying transmission theory, this relationship is shown to be a function of heart rate, peripheral resistance, and pulse wave reflection. Because this pressure-volume relationship is generally not equal to total arterial compliance, it is termed “apparent compliance.” This new concept forms the natural counterpart to the established concept of apparent pulse wave velocity.


2018 ◽  
Vol 2 (3) ◽  
pp. 27-32 ◽  
Author(s):  
Nudrath Kahkashan ◽  
Mehnaaz Sameera Arifuddin ◽  
Mohammed Abdul Hannan Hazari ◽  
Safia Sultana ◽  
Farah Fatima ◽  
...  

Physiological variation of estrogen and progesterone during menstrual cycle is well known. They not only have an effect on blood pressure control, but also seem to have a role in regulating arterial compliance. This study was done to find out whether there are any changes in central arterial parameters during different phases of menstrual cycle. Thirty female subjects in the age group of 18-22 years with normal, regular menstrual cycles participated in this prospective observational study at our teaching hospital. Anthropometric parameters were recorded. Blood pressure in all 4 limbs was recorded using cardiovascular risk analyzer-Periscope™ on Day 3rd to 5th (follicular phase), Day 12th to 14th (ovulation phase), Day 22nd to 24th (luteal phase) of their menstrual cycle. We collected blood samples during these three phases for estimation of estradiol and progesterone by ELISA technique. Analysis of variance and correlation statistics were done using SPSS 17.0 statistical software. No significant statistical changes were observed in systolic blood pressure, diastolic blood pressure, mean arterial pressure, pulse pressure, aortic systolic pressure, aortic diastolic pressure, aortic augmentation pressure, aortic index and pulse wave velocity during the three recorded phases of the menstrual cycle. There are many studies which correlate changes in peripheral artery blood pressure with different phases of menstrual cycle. But there is scarcity in data available which correlates central arterial pressures and arterial stiffness with natural hormonal variations in different phases of menstrual cycle. However, our results show that although there are subtle changes in blood pressure parameters along with estrogen and progesterone levels throughout the menstrual cycle, yet these were not statistically significant.


2020 ◽  
Vol 25 (12) ◽  
pp. 4036
Author(s):  
H. Yilmaz Ak ◽  
Y. Ozsahin ◽  
N. Baskurt Aladag ◽  
F. Gencoglu ◽  
B. Sahin Yildiz ◽  
...  

Aim. Patients with chronic inflammatory diseases (CID), such as rheumatoid arthritis (RA) and familial Mediterranean fever (FMF) are more likely to have higher risk of cardiac events. Pulse wave velocity (PWV) can be used to measure the aortic dis-tensibility and it is known as inversely related to the arterial compliance. Increased aortic stiffness which is assessed by PWV, is seem to be associated with arterial blood pressure. In this study, we investigated the arterial compliance by PWV in patients with CID including RA and FMF.Material and methods. We studied 25 patients with RA, 33 patients with FMF and 31 healthy subjects without a history of any cardiovascular risk factors such as hypertension, diabetes mellitus, hyperlipidaemia (89 subjects in total). We measured the arterial compliance by automatic carotid-femoral (aortic) PWV using Complior Colson (France) device. PWV (m/s) = distance (m)/transit time(s).Results. It is seen that, patients with CID have higher carotid-femoral (aortic) PWV (8,76±2,09 vs 8,07±0,94 m/s) compared to control groups (p=0,03). There were significant correlations between PWV and age, body-mass index, systolic blood pressure, diastolic blood pressure and mean blood pressure. (p<0,001, r=0,65; p<0,001, r=0,36; p<0,001, r=0,42; p<0,001, r=0,46; p<0,001, r=0,48, respectively).Conclusion. Arterial compliance, which is assessed by carotid-femoral (aortic) PWV, is decreased in patients with CID such as RA and FMF when it is compared to healthy control group.


1993 ◽  
Vol 72 (11) ◽  
pp. 794-798 ◽  
Author(s):  
Roland G. Asmar ◽  
Athanase Benetos ◽  
Kamel Chaouche-Teyara ◽  
Claire M. Raveau-Landon ◽  
Michel E. Safar

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