A Study of Changes in Whole-Body Calcium, Phosphorus, Sodium and Nitrogen by Neutron Activation Analysis in Vivo in Rats on a Calcium-Deficient Diet

1976 ◽  
Vol 51 (4) ◽  
pp. 399-402
Author(s):  
K. Boddy ◽  
R. Lindsay ◽  
I. Holloway ◽  
D. A. S. Smith ◽  
A. Elliott ◽  
...  
Keyword(s):  
Neutron Activation Analysis ◽  
Activation Analysis ◽  
The Body ◽  
Whole Body ◽  
Deficient Diet ◽  
Calcium Phosphorus ◽  
Dietary Period ◽  
Total Body ◽  
And Control

1. A method of measuring changes in the total body content of calcium, phosphorus, nitrogen and sodium in rats by activation analysis in vivo is described. 2. The change in the body content of the elements has been measured in rats on a calcium-deficient diet and in control animals, the body nitrogen being used to represent lean body mass for normalization. 3. There were significant differences in Ca/N and P/N but not in Ca/P ratios between the animals on a deficient diet and control animals at the end of the dietary period.

In vivo measurement of lithium in the body by a neutron activation analysis technique

1986 ◽  
Vol 13 (1) ◽  
pp. 45-49 ◽  
Author(s):  
D. Glaros ◽  
A. F. LoMonte ◽  
K. J. Ellis ◽  
S. Yasumura ◽  
R. W. Stoenner ◽  
...  
Keyword(s):  
Neutron Activation Analysis ◽  
Activation Analysis ◽  
Neutron Activation ◽  
The Body ◽  
In Vivo Measurement ◽  
Analysis Technique

Direct Determination of the Body Content of Radionuclides: Abstract

2003 ◽  
Vol 3 (1) ◽  
pp. 9-9
Author(s):  
R. Griffith ◽  
H. Bergmann ◽  
F. A. Fry ◽  
D. Hickman ◽  
J.-L. Genicot ◽  
...  
Keyword(s):  
Direct Measurement ◽  
Direct Determination ◽  
The Body ◽  
Whole Body ◽  
Control Measurement ◽  
In Vivo Measurement ◽  
Calibration Methods ◽  
Partial Body ◽  
And Control

Previous ICRU reports have dealt with the formulation and properties of tissue substitutes and phantoms that are used to calibrate in vivo measurement systems. This report provides guidance on the overall process of the direct measurement of radionuclides in the human body for radiation protection and medical applications. It addresses the detectors and electronics used for the measurement; methods of background reduction and control; measurement geometries for whole body, partial body or organ counting; physical and mathematical calibration methods; data analysis; and quality assurance. It is directed to readers who need practical advice on the establishment and operation of direct measurement facilities.

Concurrent Estimation of Total Body and Exchangeable Body Sodium in Hypertension

1978 ◽  
Vol 54 (2) ◽  
pp. 187-191 ◽  
Author(s):  
K. Boddy ◽  
J. J. Brown ◽  
D. L. Davies ◽  
A. Elliott ◽  
I. Harvey ◽  
...  
Keyword(s):  
Activation Analysis ◽  
Repeated Measurements ◽  
Exchangeable Sodium ◽  
Additional Tool ◽  
Body Sodium ◽  
Calcium Phosphorus ◽  
Sodium Metabolism ◽  
Total Body ◽  
Concurrent Estimation

1. Total-body neutron-activation analysis in vivo was carried out in 11 hypertensive subjects to measure simultaneously the total body content of sodium, chlorine, calcium, phosphorus and nitrogen. 2. There was a highly significant correlation between total body sodium measured by activation analysis and total exchangeable sodium measured by a standard isotope-dilution technique (r = 0·92, P < 0·001). Exchangeable sodium averaged 80·3% of total body sodium. 3. The measured values of chlorine, calcium, phosphorus and nitrogen were similar to those for healthy subjects reported by others. 4. Activation analysis in vivo appears promising as an additional tool for investigating sodium metabolism in hypertension, as it is the only method available for determining the total body content of this element. The radiation dose (1 rem) is sufficiently low to permit repeated measurements in the same subject.

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