Potassium Changes in Megaloblastic Anaemia

1975 ◽  
Vol 49 (1) ◽  
pp. 77-79
Author(s):  
R. Hesp ◽  
I. Chanarin ◽  
Christine E. Tait

1. Serial measurements of serum potassium and total-body potassium were made on eighteen patients with megaloblastic anaemia before the start of therapy and during the period of recovery. 2. In those patients who presented with an initial packed cell volume of less than 25%, a mean decrease in serum potassium of 0.4 mmol/l occurred on average within 2.5 days of the start of therapy. This was followed by a significant increase in serum potassium during the period of recovery. There was a significant increase in total-body potassium in these patients, but this could be explained by increases in erythrocyte mass, erythrocyte potassium concentration and lean body mass.

1984 ◽  
Vol 16 (2) ◽  
pp. 199
Author(s):  
S. W. Lichtman ◽  
K. R. Segal ◽  
R. L. Ruskin ◽  
E. Presta ◽  
J. Wang ◽  
...  

1996 ◽  
Vol 17 (3) ◽  
pp. 106-106
Author(s):  
Kenneth B. Roberts

Potassium is the major intracellular cation; only a very small fraction of total body potassium is in the intravascular space. Increased potassium concentration in serum is infrequent in pediatrics, but it can be life-threatening because of its effect on membrane potentials, particularly of heart muscle. The serum potassium concentration is affected primarily by the kidney. Potassium is filtered by the glomerulus, then reabsorbed and secreted by the tubule. Processes that interfere with filtration or secretion (eg, acute on chronic glomerulonephritis, interstitial nephritis) may cause hyperkalemia; processes that interfere with reabsorption may cause hypokalemia. The most common cause of an increased serum potassium is "pseudohyperkalemia" due to hemolysis or to tissue hypoxia distal to the placement of a tourniquet.


1974 ◽  
Vol 46 (4) ◽  
pp. 449-456 ◽  
Author(s):  
K. Boddy ◽  
R. Hume ◽  
Priscilla C. King ◽  
Elspeth Weyers ◽  
T. Rowan

1. Total body potassium was measured in professional football players before the football season began and at approximately mid-season. The values obtained were significantly higher than in healthy subjects taking only average exercise. There was a significant increase in body potassium as the season progressed. 2. Lean body mass was estimated by four methods and the results were compared. The values of lean body mass, as a percentage of body weight, were significantly higher than in healthy control subjects taking only average exercise and they also increased significantly over the period of the study. 3. The mean erythrocyte potassium concentration was lower pre-season than at mid-season and the pre-season value was also significantly less than in healthy controls. The values before and after vigorous exercise were not significantly different. 4. Conversely, the pre-season mean plasma potassium concentration was significantly higher than in control subjects and than the mid-season value. The mean plasma potassium concentration was higher before vigorous exercise than immediately afterwards. 5. The leucocyte count increased significantly after vigorous exercise, correlating with a decrease in leucocyte ascorbic acid content.


1970 ◽  
Vol 1 (04) ◽  
pp. 447-451 ◽  
Author(s):  
Agneta Borgstedt ◽  
Gilbert Forbes ◽  
Julio Reina

2002 ◽  
Vol 57 (3) ◽  
pp. 107-114 ◽  
Author(s):  
Pauline L. Martin ◽  
Joan Lane ◽  
Louise Pouliot ◽  
Malcolm Gains ◽  
Rudolph Stejskal ◽  
...  

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