Electrical Potential Difference and Sodium Transport in Human Colon and Rectum

1972 ◽  
Vol 42 (5) ◽  
pp. 24P-24P
Author(s):  
C. J. Edmonds ◽  
Diana Pilcher
Keyword(s):  
Sodium Transport ◽  
Electrical Potential ◽  
Human Colon ◽  
Potential Difference ◽  
Electrical Potential Difference ◽  
Colon And Rectum

scholarly journals Transmural electrical potential difference of the human colon

Gut ◽  
1969 ◽  
Vol 10 (11) ◽  
pp. 921-923 ◽  
Author(s):  
M. G. Geall ◽  
R. J. Spencer ◽  
S. F. Phillips
Keyword(s):  
Electrical Potential ◽  
Human Colon ◽  
Potential Difference ◽  
Electrical Potential Difference

scholarly journals Transmural electrical potential difference in the mammalian esophagus in vivo

1978 ◽  
Vol 75 (2) ◽  
pp. 286-291 ◽  
Author(s):  
Keith S. Turner ◽  
Don W. Powell ◽  
Charles N. Carney ◽  
Roy C. Orlando ◽  
Eugene M. Bozymski
Keyword(s):  
Electrical Potential ◽  
Potential Difference ◽  
Electrical Potential Difference

Electrical potential difference between exocelomic fluid and maternal blood in early pregnancy

1998 ◽  
Vol 274 (5) ◽  
pp. R1492-R1495 ◽  
Author(s):  
Stuart Ward ◽  
Eric Jauniaux ◽  
Claire Shannon ◽  
Charles Rodeck ◽  
Robert Boyd ◽  
...  
Keyword(s):  
Electrical Potential ◽  
Extracellular Fluid ◽  
First Trimester ◽  
Maternal Blood ◽  
Potential Difference ◽  
Electrical Potential Difference ◽  
Amniotic Cavity ◽  
Normal Human ◽  
The Mean ◽  
Forearm Vein

The forces that drive transfer of solutes between maternal blood and embryo in early human pregnancy are poorly understood. The aim of this study was to determine whether there is an electrical potential difference (PD) between maternal blood and the exocelomic cavity and between maternal blood and the amniotic cavity in the normal human conceptus at or before 10 wk of pregnancy. We measured PD between a saline-filled catheter in a forearm vein of women undergoing termination of pregnancy for psychological reasons in the first trimester and a second saline-filled catheter in the exocelomic cavity or amniotic cavity of their conceptus. The mean (±SE) maternal blood/exocelomic cavity PD in eight women was 8.7 ± 1.0 mV and the mean maternal blood/amniotic cavity PD in four of the women was 6.7 ± 1.3 mV, embryo side negative for both sets of measurement. These data show that there is a PD between maternal and embryonic extracellular fluid in the first trimester that will directly influence exchange of ions between the two compartments.

Changes in electrical potential difference of rectal mucosa and of gallbladder bile constituents of dogs fed chenodeoxycholic acid

1986 ◽  
Vol 64 (8) ◽  
pp. 1115-1118
Author(s):  
J. Patrick Shoenut
Keyword(s):  
Chenodeoxycholic Acid ◽  
Dose Group ◽  
Low Dose ◽  
Electrical Potential ◽  
Rectal Mucosa ◽  
Gallbladder Bile ◽  
Potential Difference ◽  
Control Group ◽  
Electrical Potential Difference ◽  
Dissolution Studies

Eighteen dogs were studied for 54 days. Rectal mucosal electrical potential difference (PD), gallbladder bile acids, cholesterol, and phospholipids were measured. It was shown that feeding chenodeoxycholic acid (CDCA) for 24 days in dosages of 15, 30, and 60 mg/kg of body weight, all depressed PD equally but significantly (P < 0.05) in three groups of dogs compared with a control group. This depression was reversible 24 days after CDCA ingestion ceased in the two highest dosages. The low dose group was sacrificed after 24 days of CDCA feeding and the gallbladder bile was analyzed. CDCA and cholesterol were each significantly (P < 0.05) elevated over control values in the gallbladder bile of these dogs. Phospholipids were not significantly changed. The PD, a reflection of Na+–K+ ATPase activity, may be a useful indicator in maximizing dosages of CDCA in gallstone dissolution studies.

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