Iron Metabolism in Patients with Chronic Renal Failure on Regular Dialysis Treatment

1971 ◽  
Vol 41 (4) ◽  
pp. 345-351 ◽  
Author(s):  
D. H. Lawson ◽  
K. Boddy ◽  
P. C. King ◽  
A. L. Linton ◽  
G. Will
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Iron Metabolism ◽  
Oral Absorption ◽  
The Body ◽  
Whole Body ◽  
Dialysis Treatment ◽  
Regular Dialysis Treatment ◽  
Considerable Controversy

1. By using a whole-body monitoring technique iron metabolism has been investigated in patients suffering from chronic renal failure who required regular dialysis treatment. 2. Oral absorption of inorganic iron was low. 3. The incorporation of radioactive iron into erythrocytes was diminished. 4. The rate of loss of radioactive iron from the body was significantly greater than in normal control and non-dialysed patients with chronic renal failure. 5. Iron exchange between dialysate and patient was studied. Patients with chronic renal failure are known to have a decreased rate of erythropoiesis and to develop abnormalities in iron metabolism (Kaye, 1958; Logue, Lange & Moore, 1958; Boddy, Lawson, Linton & Will, 1970). However, considerable controversy exists about the effect of haemodialysis on iron metabolism in such patients (Shaldon, 1966; Eschbach, Funk, Adamson, Kuhn, Scribner & Finch, 1967; Eschbach, Cook & Finch, 1970). The use of a whole-body monitor permitted measurement in a single study of the oral absorption of a tracer dose of 59Fe, its incorporation into erythrocytes and the subsequent long-term rate of loss of 59Fe from the body. We have previously reported the results of an investigation of iron metabolism by using this method in patients with chronic renal failure (Boddy et al., 1970). We now report the results of a similar investigation of iron metabolism in patients with chronic renal failure undergoing regular haemodialysis therapy.

Iron Metabolism after Renal Transplantation

1973 ◽  
Vol 44 (1) ◽  
pp. 27-32 ◽  
Author(s):  
K. Boddy ◽  
G. Will ◽  
D. H. Lawson ◽  
Priscilla C. King ◽  
A. L. Linton
Keyword(s):  
Renal Failure ◽  
Renal Transplantation ◽  
Chronic Renal Failure ◽  
Iron Metabolism ◽  
Oral Absorption ◽  
Normal Subjects ◽  
The Body ◽  
Whole Body ◽  
The Mean

1. The oral absorption and the rate of loss from the body of radioactive iron were measured by whole-body monitoring in patients with functioning renal homografts. The incorporation of radioactive iron into erythrocytes was also measured. 2. The results were compared with corresponding values in normal subjects and in non-dialysed and dialysed patients with chronic renal failure. 3. The mean oral absorption and incorporation into erythrocytes of radioactive iron was intermediate between that of normal subjects and of both non-dialysed and dialysed patients with chronic renal failure. 4. The mean rate of loss from the body was not significantly different from that in normal subjects and non-dialysed patients with chronic renal failure but it was significantly less than that in dialysed patients.

Iron Metabolism in Patients with Chronic Renal Failure

1970 ◽  
Vol 39 (1) ◽  
pp. 115-121 ◽  
Author(s):  
K. Boddy ◽  
D. H. Lawson ◽  
A. L. Linton ◽  
G. Will
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Iron Deficiency ◽  
Iron Metabolism ◽  
Normal Subjects ◽  
The Body ◽  
Whole Body ◽  
Red Cell ◽  
Monitoring Technique

1. Iron metabolism has been investigated in patients suffering from chronic renal failure, using a whole body monitoring technique. 2. Absorption of labelled inorganic iron was decreased. 3. Radio-iron was lost from the body at a rate comparable to that found in normal subjects. 4. The red cell incorporation of radioactive iron was diminished. 5. The results suggest that anaemia in these patients was due to decreased erythropoiesis and not due to iron deficiency despite the evidence of markedly abnormal iron handling presented.

scholarly journals Clinical aspects of chronic renal failure at the initiation of regular dialysis treatment

1988 ◽  
Vol 21 (7) ◽  
pp. 613-619
Author(s):  
Akira Oya ◽  
Shigeru Miyagata ◽  
Ryuuzou Kato ◽  
Tadashi Harada ◽  
Seigi Tsuchida
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Clinical Aspects ◽  
Dialysis Treatment ◽  
Regular Dialysis Treatment

scholarly journals PENGETAHUAN MASYARAKAT TENTANG EFEK JANGKA PANJANG PENGGUNAAN JAMU PADA RESIKO GAGAL GINJAL KRONIK DI DESA MILANGASRI RT 05/01 KECAMATAN PANEKAN KABUPATEN MAGETAN

2018 ◽  
Vol 2 (1) ◽  
pp. 131
Author(s):  
Umi Isnayati Rohmatin ◽  
Laily Isro'in ◽  
Rika Maya Sari
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Herbal Medicine ◽  
Knowledge Society ◽  
Sampling Technique ◽  
The Body ◽  
Public Knowledge ◽  
Long Term Effects ◽  
Purposive Sampling

AbstrackPeople have been assuming that herbs are safer and lesser side effects, but it must be understood that herbs may not be safe for the body. Lack of public knowledge about the ingredients of herbs that are unknown. Society has not known that there are some herbs mixed by chemicals that are harmful to the body. This study aims to find out how the public knowledge about the long-term effects of herbal medicine on the risk of chronic renal failure (ggk).The research design used was descriptive, with a population of a sample of 148 people. The sampling technique used is purposive sampling with total sample of 30 respondents. Methods of data collection using questionnaires then performed data processed and analizyed based on percentage.The result of study on 30 respondents shows that most of the 16 respondent (53,3%) knowledgeable good, and a small portion 14 respondents (46,6%) knowladgeable bad.The result concluded that must people have a good knowledge about the long-term effects of herbal medicine use. The result showed that the level of community knowledge is influenced by various factors such as age, education, information, and information sources. Recommed for further research to examine the relationship of people who consume herbal medicine with chronic renal failure. Keyword : Knowledge, Society, Herb, Chronic Renal Failure AbstrakMasyarakat selama ini beranggapan bahwa jamu lebih aman dikonsumsi dan lebih kecil efek sampingnya, namun harus tetap dipahami bahwa jamu bisa saja tidak aman bagi tubuh. Kurangnya pengetahuan masyarakat tentang kandungan jamu yang tanpa diketahui kandungannya. Masyarakat selama ini tidak tahu bahwa ada beberapa jamu yang dicampur oleh bahan kimia yang berbahaya bagi tubuh. Penelitian bertujuan untuk mengetahui bagaimana pengetahuan masyarakat tentang efek jangka panjang penggunaan jamu pada resiko gagal ginjal kronik. Desain penelitian yang digunakan adalah deskriptif dengan populasi sejumlah148 warga. Teknik sampling yang digunakan adalah purposive sampling dengan jumlah sampel sebanyak 30 responden. Teknik pengumpulan data menggunakan kuisioner dan analisa data menggunakan analisa prosentase.Hasil penelitian menunjukkan bahwa sebagian besar 16 responden (53,3%) berpengetahuan baik, dan sebagiankecil14 responden (46,6%) berpengetahuan buruk.Hasil penelitian dapat disimpulkan bahwa sebagian besar masyarakat memiliki pengetahuan yang baik tentang efek jangka panjang penggunaan jamu. Hasil penelitian menunjukkan bahwa tingkat pengetahuan masyarakat dipengaruhi oleh berbagai faktor seperti usia, pendidikan, informassi, dan sumber informasi.Untuk peneliti selanjutnya direkomendasikan dapat meneliti hubungan masyarakat yang mengkonsumsi jamu dengan gagal ginjal kronik.Kata Kunci : Pengetahuan, Masyarakat, Jamu, Resiko Gagal Ginjal Kronik.

Long-term adaptive responses to dietary protein restriction in chronic renal failure

1995 ◽  
Vol 268 (4) ◽  
pp. E668-E677 ◽  
Author(s):  
K. Tom ◽  
V. R. Young ◽  
T. Chapman ◽  
T. Masud ◽  
L. Akpele ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Dietary Protein ◽  
Protein Turnover ◽  
Whole Body ◽  
Dietary Therapy ◽  
Term Therapy ◽  
Body Protein ◽  
Long Term Therapy

Six patients with chronic renal failure (glomerular filtration rate 18 +/- 2 ml/min) underwent two 10-day admissions separated by at least 1 yr of outpatient therapy with a very low-protein diet (VLPD) providing 0.28 g protein.kg-1.day-1 plus an amino acid-ketoacid supplement. During each Clinical Research Center admission, subjects completed a 5-day nitrogen balance (BN), and whole body protein turnover was measured during fasting and feeding using intravenous [1-13C]leucine and intragastric [5,5,5-2H3]leucine. Outpatient dietary protein compliance was very good (25 vs. 20 g protein/day or 125% goal), whereas energy intake was only 69% of goal (24 vs. 35 kcal.kg-1.day-1). During the 16 +/- 2 mo of dietary therapy, there were no changes in serum proteins or anthropometrics. BN after > or = 1 yr of dietary therapy was neutral and did not differ from initial values (+0.46 +/- 0.20 vs. +0.55 +/- 0.19 g N/day). Similarly, rates of whole body protein synthesis, degradation, and leucine oxidation after long-term therapy with the VLPD regimen did not differ from baseline values, and neutral BN was maintained by a marked suppression of amino acid oxidation and postprandial inhibition of protein degradation. This is the first evidence that the compensatory changes in whole body protein turnover activated in response to dietary protein restriction are sustained during long-term therapy.

TESTICULAR ANDROGEN PRODUCTION UNDER LONG-TERM HCG TREATMENT IN ADULTS WITH CHRONIC RENAL FAILURE

1975 ◽  
Vol 80 (1_Suppla) ◽  
pp. S141 ◽  
Author(s):  
H. D. Bundschu ◽  
E. H. Pfeiffer ◽  
M. Eichner ◽  
K. Hayduk
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure

scholarly journals The pulsatility index and the resistive index in renal arteries. Associations with long-term progression in chronic renal failure

1997 ◽  
Vol 12 (7) ◽  
pp. 1376-1380 ◽  
Author(s):  
L. J. Petersen ◽  
J. R. Petersen ◽  
U. Talleruphuus ◽  
S. D. Ladefoged ◽  
J. Mehlsen ◽  
...  
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Pulsatility Index ◽  
Resistive Index ◽  
Renal Arteries

Even moderate chronic renal failure is associated with impaired acute and long-term outcome after coronary angioplasty

Nephrology ◽  
2003 ◽  
Vol 8 (3) ◽  
pp. 110-115 ◽  
Author(s):  
HOLGER REINECKE ◽  
ANDREA REGETMEIER ◽  
FRITZ MATZKIES ◽  
GUNTER BREITHARDT ◽  
ROLAND M SCHAEFER
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Coronary Angioplasty ◽  
Term Outcome ◽  
Long Term Outcome

Bronchial Reactivity in Patients Undergoing Long-Term Haemodialysis for Chronic Renal Failure

1991 ◽  
Vol 9 (2) ◽  
pp. 70-73 ◽  
Author(s):  
M.J. Walshaw ◽  
R. Lim ◽  
R. Ahmad ◽  
C.R.K. Hind
Keyword(s):  
Renal Failure ◽  
Chronic Renal Failure ◽  
Bronchial Reactivity
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