Genes expression profiling of peripheral blood cells of patients with hepatocellular carcinoma

2012 ◽  
Vol 36 (9) ◽  
pp. 803-809 ◽  
Author(s):  
Peng‑jun Zhang ◽  
Run Wei ◽  
Xin‑yu Wen ◽  
Liang Ping ◽  
Cheng‑bin Wang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Peripheral Blood ◽  
Expression Profiling ◽  
Blood Cells ◽  
Peripheral Blood Cells ◽  
Genes Expression ◽  
Genes Expression Profiling

scholarly journals Gene Expression Profiling in Peripheral Blood Cells and Synovial Membranes of Patients with Psoriatic Arthritis

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0128262 ◽  
Author(s):  
Marzia Dolcino ◽  
Andrea Ottria ◽  
Alessandro Barbieri ◽  
Giuseppe Patuzzo ◽  
Elisa Tinazzi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Psoriatic Arthritis ◽  
Gene Expression Profiling ◽  
Peripheral Blood ◽  
Expression Profiling ◽  
Blood Cells ◽  
Peripheral Blood Cells ◽  
Synovial Membranes

scholarly journals Isolation and Expression Profiling of Genes Upregulated in the Peripheral Blood Cells of Systemic Lupus Erythematosus Patients

DNA Research ◽  
2005 ◽  
Vol 12 (6) ◽  
pp. 429-439 ◽  
Author(s):  
Taeko Ishii ◽  
Hiroaki Onda ◽  
Akie Tanigawa ◽  
Shiro Ohshima ◽  
Hiroshi Fujiwara ◽  
...  
Keyword(s):  
Systemic Lupus Erythematosus ◽  
Lupus Erythematosus ◽  
Peripheral Blood ◽  
Expression Profiling ◽  
Blood Cells ◽  
Peripheral Blood Cells ◽  
Systemic Lupus

Prognostic significance of hematopoietic-cell serglycin for survival of hepatocellular carcinoma: a single-center retrospective study

2020 ◽  
Vol 23 ◽  
Author(s):  
Yue Li ◽  
Hongjie Chen ◽  
Huiqiong Lu ◽  
Zengcheng Zou ◽  
Yongwei Li
Keyword(s):  
Hepatocellular Carcinoma ◽  
Bacterial Infection ◽  
Peripheral Blood ◽  
Blood Cells ◽  
Cox Regression ◽  
Prognostic Significance ◽  
Control Group ◽  
Peripheral Blood Cells ◽  
Blood Proteins ◽  
Roc Curve Analysis

Aim and Objective: Inflammation-related changes in peripheral blood cells and blood proteins are prognostic factors for survival in hepatocellular carcinoma (HCC), but their usefulness is limited by active bacterial infection. This study investigated whether infection interfered with the predictive value of serglycin, a proteoglycan found in hematopoietic cells, on survival in HCC. Materials and Methods: Patients with hepatitis B virus (HBV)-induced HCC, 100 without and 30 with bacterial infection, and 30 healthy adult controls were enrolled retrospectively. Baseline clinical data collected before treatment with transarterial chemoembolization (TACE) was evaluated and serglycin expression was assayed by flow cytometry. Receiver operating characteristic (ROC) curve analysis identified serglycin cutoff values for patient stratification. Cox regression and Kaplan– Meier analyses were performed to identify predictors of overall survival (OS). Results: Serglycin levels in peripheral blood cells were higher in both groups of HCC patients than in the control group. Cholinesterase, lung metastasis, average neutrophil serglycin fluorescence intensity, and aspartate aminotransferase levels were associated with survival risk. Barcelona Clinic Liver Cancer stage A was associated a good prognosis of OS. Conclusion: The intensity of serglycin fluorescence in peripheral neutrophils was independently predictive of survival in HCC and its value was not limited by bacterial infection. The method presented here is a simple and feasible way to predict prognosis in HCC patients with TACE.

scholarly journals Gene expression profiling of peripheral blood cells for early detection of breast cancer

2010 ◽  
Vol 12 (1) ◽  
Author(s):  
Jørgen Aarøe ◽  
Torbjørn Lindahl ◽  
Vanessa Dumeaux ◽  
Solve Sæbø ◽  
Derek Tobin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Gene Expression ◽  
Early Detection ◽  
Gene Expression Profiling ◽  
Peripheral Blood ◽  
Expression Profiling ◽  
Blood Cells ◽  
Peripheral Blood Cells
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