Anthocyanin-rich extract from black rice inhibits colon cancer formation in mice

2010 ◽  
Vol 34 (8) ◽  
pp. S44-S44
Author(s):  
Bo Dong ◽  
Xinmei Zhou ◽  
Xun Xu ◽  
Huang Xu ◽  
Yongxia Zheng ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Black Rice

scholarly journals Antioxidative Properties and Cytotoxic Activity Against Colon Cancer Cell WiDr of Rhizopus Oryzae and Rhizopus Oligosporus-Fermented Black Rice Bran Extract

2018 ◽  
Vol 6 (1) ◽  
pp. 23-34 ◽  
Author(s):  
Kristian Edo Zulfafamy ◽  
Ardiansyah Ardiansyah ◽  
Slamet Budijanto
Keyword(s):  
Colon Cancer ◽  
Cancer Cell ◽  
Bioactive Compounds ◽  
Rice Bran ◽  
Antiproliferative Activity ◽  
Rhizopus Oryzae ◽  
Colon Cancer Cell ◽  
Total Phenolic ◽  
Black Rice ◽  
Black Rice Bran

Black rice bran (BRB) was reported to have several bioactive compounds which can potentially as antioxidant and reduce the colon cancer incidence. Fermentation was reported to be able to increase bioavailability through deliberating the bioactive compounds from the cellular matrix. The aim of this study was to improve the bioavailability of BRB bioactive compounds which offer beneficial health properties as antiproliferative against colon cancer cell WiDr and confer antioxidant activity by fermentation. The study was conducted in 4 groups of different condition: non-fermented, the use of R. oryzae, R. oligosporus, and combination of R. oryzae + R. oligosporus for fermentation starter, respectively. BRB fermentation was conducted in 72 and 96 hours. Each of fermented BRB (FBRB) was then extracted by using 70% ethanol and methanol, respectively. Extracts derived from FBRB were evaluated for their availability of total phenolic content (TPC) by using total phenolic analysis, antioxidative activity by using DPPH and FRAP assay, and antiproliferative properties toward colon cancer WiDr by using MTT assay. The result of these studies showed that an increased amount of TPC of the ethanolic and methanolic extract of FBRB when compared to non-fermented BRB (NFBRB). Consequently, DPPH and FRAP antioxidant capacity of FBRB was higher than that of NFBRB. The antiproliferative activity of FBRB against colon cancer cells, WiDr, was also shown to be higher activity than that of NFBRB (As shown on IC50 extract). This results indicated that BRB could optimally increase its antioxidant and antiproliferative activity by fermentation.

VEGF is regulated by the WNT pathway in colon cancer

2001 ◽  
Vol 120 (5) ◽  
pp. A4-A4
Author(s):  
X ZHANG ◽  
J GASPARD ◽  
D CHUNG
Keyword(s):  
Colon Cancer ◽  
Wnt Pathway

NF-κB regulates colon cancer cell proliferation and tumorigenicity

2001 ◽  
Vol 120 (5) ◽  
pp. A615-A615
Author(s):  
S KUWADA ◽  
C SCAIFE ◽  
J KUANG ◽  
R DAYNES
Keyword(s):  
Colon Cancer ◽  
Cell Proliferation ◽  
Cancer Cell ◽  
Colon Cancer Cell ◽  
Cancer Cell Proliferation

Leptin is a growth factor for human colon cancer cells

2001 ◽  
Vol 120 (5) ◽  
pp. A493-A493
Author(s):  
J HARDWICK ◽  
G VANDENBRINK ◽  
S VANDEVENTER ◽  
M PEPPELENBOSCH
Keyword(s):  
Colon Cancer ◽  
Growth Factor ◽  
Cancer Cells ◽  
Human Colon ◽  
Colon Cancer Cells ◽  
Human Colon Cancer ◽  
Human Colon Cancer Cells

IBD With Cholangitis May Portend Colon Cancer

2011 ◽  
Vol 44 (1) ◽  
pp. 48
Author(s):  
DENISE NAPOLI
Keyword(s):  
Colon Cancer
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