Tethered-bilayer lipid membranes as a support for membrane-active peptides

2001 ◽  
Vol 29 (4) ◽  
pp. 613-617 ◽  
Author(s):  
B. A. Cornell ◽  
G. Krishna ◽  
P. D. Osman ◽  
R. D. Pace ◽  
L. Wieczorek
Keyword(s):  
Ion Channels ◽  
Present Article ◽  
Lipid Membranes ◽  
Gold Electrode ◽  
Lipid Membrane ◽  
Bilayer Lipid Membranes ◽  
Active Peptides ◽  
Bilayer Lipid ◽  
Membrane Active Peptides ◽  
Key Steps

An immunosensing device, comprising a lipid membrane incorporating ion channels tethered to the surface of a gold electrode, has been reported [Cornell, Braach-Maksvytis, King, Osman, Raguse, Wieczorek and Pace (1997) Nature (London) 387, 580–583]. The present article describes key steps in the assembly of the device and provides further evidence for its proposed sensing mechanism.

Impact of membrane protein-lipid interactions on formation of bilayer lipid membranes on SAM-modified gold electrode

2021 ◽  
Vol 373 ◽  
pp. 137888
Author(s):  
Masaru Kato ◽  
Yuya Masuda ◽  
Narumi Yoshida ◽  
Takehiko Tosha ◽  
Yoshitsugu Shiro ◽  
...  
Keyword(s):  
Membrane Protein ◽  
Lipid Membranes ◽  
Gold Electrode ◽  
Bilayer Lipid Membranes ◽  
Lipid Interactions ◽  
Bilayer Lipid

Self-Healing Bilayer Lipid Membranes Formed Over Synthetic Substrates

2008 ◽  
Author(s):  
M. Austin Creasy ◽  
Donald J. Leo
Keyword(s):  
Self Assembly ◽  
Lipid Membranes ◽  
Lipid Membrane ◽  
Bilayer Lipid Membrane ◽  
Unique Property ◽  
Bilayer Lipid Membranes ◽  
Self Healing ◽  
Electrical Field ◽  
Bilayer Lipid ◽  
Recent Experimental Study

Biological systems demonstrate autonomous healing of damage and are an inspiration for developing self-healing materials. Our recent experimental study has demonstrated that a bilayer lipid membrane (BLM), also called a black lipid membrane, has the ability to self-heal after mechanical failure. These molecules have a unique property that they spontaneously self assembly into organized structures in an aqueous medium. The BLM forms an impervious barrier to ions and fluid between two volumes and strength of the barrier is dependent on the pressure and electrical field applied to the membrane. A BLM formed over an aperture on a silicon substrate is shown to self-heal for 5 pressurization failure cycles.

scholarly journals Cluster Organization of Ion Channels Formed by the Antibiotic Syringomycin E in Bilayer Lipid Membranes

1998 ◽  
Vol 74 (6) ◽  
pp. 2918-2925 ◽  
Author(s):  
Yuri A. Kaulin ◽  
Ludmila V. Schagina ◽  
Sergey M. Bezrukov ◽  
Valery V. Malev ◽  
Alexander M. Feigin ◽  
...  
Keyword(s):  
Ion Channels ◽  
Lipid Membranes ◽  
Bilayer Lipid Membranes ◽  
Syringomycin E ◽  
Bilayer Lipid ◽  
Cluster Organization

Bilayer lipid membranes supported on Teflon filters: A functional environment for ion channels

2011 ◽  
Vol 26 (7) ◽  
pp. 3127-3135 ◽  
Author(s):  
Thai Phung ◽  
Yanli Zhang ◽  
James Dunlop ◽  
Julie Dalziel
Keyword(s):  
Ion Channels ◽  
Lipid Membranes ◽  
Bilayer Lipid Membranes ◽  
Bilayer Lipid
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