IDENTIFICATION AND CHARACTERIZATION OF A MAJOR BUILDING BLOCK IN THE FUNGAL CELL WALL

1997 ◽  
Vol 25 (3) ◽  
pp. 419S-419S
Author(s):  
Frans M. Klis ◽  
L. Heleen P. Caro ◽  
Jack H. Vossen ◽  
M. Van Der Vaart ◽  
Herman Van Den Ende
1997 ◽  
Vol 25 (3) ◽  
pp. 856-860 ◽  
Author(s):  
F. M. Klis ◽  
L. H. P. Caro ◽  
J. H. Vossen ◽  
J. C. Kapteyn ◽  
A. F. J. Ram ◽  
...  

2020 ◽  
Vol 21 (23) ◽  
pp. 8996
Author(s):  
Renata Teparić ◽  
Mateja Lozančić ◽  
Vladimir Mrša

Fungal cell walls are composed of a polysaccharide network that serves as a scaffold in which different glycoproteins are embedded. Investigation of fungal cell walls, besides simple identification and characterization of the main cell wall building blocks, covers the pathways and regulations of synthesis of each individual component of the wall and biochemical reactions by which they are cross-linked and remodeled in response to different growth phase and environmental signals. In this review, a survey of composition and organization of so far identified and characterized cell wall components of different yeast genera including Saccharomyces, Candida, Kluyveromyces, Yarrowia, and Schizosaccharomyces are presented with the focus on their cell wall proteomes.


2019 ◽  
Vol 19 (10) ◽  
pp. 812-830 ◽  
Author(s):  
P. Marie Arockianathan ◽  
Monika Mishra ◽  
Rituraj Niranjan

The developing resistance in fungi has become a key challenge, which is being faced nowadays with the available antifungal agents in the market. Further search for novel compounds from different sources has been explored to meet this problem. The current review describes and highlights recent advancement in the antifungal drug aspects from plant and marine based sources. The current available antifungal agents act on specific targets on the fungal cell wall, like ergosterol synthesis, chitin biosynthesis, sphingolipid synthesis, glucan synthesis etc. We discuss some of the important anti-fungal agents like azole, polyene and allylamine classes that inhibit the ergosterol biosynthesis. Echinocandins inhibit β-1, 3 glucan synthesis in the fungal cell wall. The antifungals poloxins and nikkomycins inhibit fungal cell wall component chitin. Apart from these classes of drugs, several combinatorial therapies have been carried out to treat diseases due to fungal resistance. Recently, many antifungal agents derived from plant and marine sources showed potent activity. The renewed interest in plant and marine derived compounds for the fungal diseases created a new way to treat these resistant strains which are evident from the numerous literature publications in the recent years. Moreover, the compounds derived from both plant and marine sources showed promising results against fungal diseases. Altogether, this review article discusses the current antifungal agents and highlights the plant and marine based compounds as a potential promising antifungal agents.


2021 ◽  
pp. 2100110
Author(s):  
Liyuan Zhang ◽  
Mengchen Zhang ◽  
Gongping Liu ◽  
Wanqin Jin ◽  
Xiaoyan Li

Sign in / Sign up

Export Citation Format

Share Document