Secondary structure and conformational changes associated with substrate-binding and the N-terminus in cyclic GMP-dependent protein kinase

JOHN P. HUGGINS; WOLFGANG LANDGRAF; FRANZ HOFMANN; JOHN T. PELTON

doi:10.1042/bst019163s

Secondary structure and conformational changes associated with substrate-binding and the N-terminus in cyclic GMP-dependent protein kinase

Biochemical Society Transactions ◽

10.1042/bst019163s ◽

1991 ◽

Vol 19 (2) ◽

pp. 163S-163S

Author(s):

JOHN P. HUGGINS ◽

WOLFGANG LANDGRAF ◽

FRANZ HOFMANN ◽

JOHN T. PELTON

Keyword(s):

Protein Kinase ◽

Secondary Structure ◽

Conformational Changes ◽

Cyclic Gmp ◽

Substrate Binding ◽

Dependent Protein Kinase ◽

N Terminus ◽

Dependent Protein

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Effects of cyclic GMP on the secondary structure of cyclic GMP dependent protein kinase and an analysis of the enzymes and amino-terminal domain by far-ultraviolet circular dichroism

Biochemistry ◽

10.1021/bi00494a024 ◽

1990 ◽

Vol 29 (42) ◽

pp. 9921-9928 ◽

Cited By ~ 37

Author(s):

Wolfgang Landgraf ◽

Franz Hofmann ◽

John T. Pelton ◽

John P. Huggins

Keyword(s):

Protein Kinase ◽

Secondary Structure ◽

Cyclic Gmp ◽

Dependent Protein Kinase ◽

Amino Terminal ◽

Terminal Domain ◽

Dependent Protein ◽

Far Ultraviolet ◽

Amino Terminal Domain ◽

Circular Dichroïsm

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Faculty Opinions recommendation of The cyclic GMP-dependent protein kinase EGL-4 regulates olfactory adaptation in C. elegans.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1011497.180814 ◽

2003 ◽

Author(s):

Randolf Menzel

Keyword(s):

Protein Kinase ◽

Cyclic Gmp ◽

Dependent Protein Kinase ◽

C Elegans ◽

Dependent Protein ◽

Olfactory Adaptation

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Bovine lung cyclic GMP-dependent protein kinase exhibits two types of specific cyclic GMP-binding sites.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)83818-8 ◽

1982 ◽

Vol 257 (10) ◽

pp. 5589-5593

Author(s):

C W Mackenzie

Keyword(s):

Protein Kinase ◽

Cyclic Gmp ◽

Binding Sites ◽

Dependent Protein Kinase ◽

Dependent Protein

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Studies on the cyclic GMP-dependent protein kinase from bovine aorta. Possible existence of a catalytic subunit.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)40271-7 ◽

1977 ◽

Vol 252 (12) ◽

pp. 4347-4353

Author(s):

M Shoji ◽

J G Patrick ◽

J Tse ◽

J F Kuo

Keyword(s):

Protein Kinase ◽

Cyclic Gmp ◽

Catalytic Subunit ◽

Dependent Protein Kinase ◽

Dependent Protein

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Mechanism of platelet inhibition by nitric oxide: In vivo phosphorylation of thromboxane receptor by cyclic GMP-dependent protein kinase

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.95.9.4888 ◽

1998 ◽

Vol 95 (9) ◽

pp. 4888-4893 ◽

Cited By ~ 165

Author(s):

G.-R. Wang ◽

Y. Zhu ◽

P. V. Halushka ◽

T. M. Lincoln ◽

M. E. Mendelsohn

Keyword(s):

Nitric Oxide ◽

Protein Kinase ◽

Cyclic Gmp ◽

Platelet Inhibition ◽

Dependent Protein Kinase ◽

Thromboxane Receptor ◽

Dependent Protein

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Molecular properties and mode of action of homogeneous preparation of stimulatory modulator of cyclic GMP-dependent protein kinase from the heart.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)34818-4 ◽

1978 ◽

Vol 253 (10) ◽

pp. 3427-3434

Author(s):

M. Shoji ◽

N.L. Brackett ◽

J. Tse ◽

R. Shapira ◽

J.F. Kuo

Keyword(s):

Protein Kinase ◽

Cyclic Gmp ◽

Mode Of Action ◽

Molecular Properties ◽

Dependent Protein Kinase ◽

Dependent Protein ◽

Homogeneous Preparation

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Cloning and expression of a novel cyclic GMP-dependent protein kinase from mouse brain

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)38689-2 ◽

1993 ◽

Vol 268 (18) ◽

pp. 13586-13591

Author(s):

M.D. Uhler

Keyword(s):

Protein Kinase ◽

Mouse Brain ◽

Cyclic Gmp ◽

Cloning And Expression ◽

Dependent Protein Kinase ◽

Dependent Protein

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Cyclic GMP-dependent Protein Kinase Iα Inhibits Thrombin Receptor-mediated Calcium Mobilization in Vascular Smooth Muscle Cells

Journal of Biological Chemistry ◽

10.1074/jbc.m512770200 ◽

2006 ◽

Vol 281 (13) ◽

pp. 8409-8416 ◽

Cited By ~ 20

Author(s):

Eva N. Christensen ◽

Michael E. Mendelsohn

Keyword(s):

Smooth Muscle ◽

Protein Kinase ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Cyclic Gmp ◽

Muscle Cells ◽

Thrombin Receptor ◽

Dependent Protein Kinase ◽

Dependent Protein

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Influence of Myristoylation, Phosphorylation, and Deamidation on the Structural Behavior of the N-Terminus of the Catalytic Subunit of CAMP-Dependent Protein Kinase†

Biochemistry ◽

10.1021/bi0021277 ◽

2001 ◽

Vol 40 (1) ◽

pp. 225-231 ◽

Cited By ~ 30

Author(s):

Andreas Tholey ◽

Rüdiger Pipkorn ◽

Dirk Bossemeyer ◽

Volker Kinzel ◽

Jennifer Reed

Keyword(s):

Protein Kinase ◽

Catalytic Subunit ◽

Structural Behavior ◽

Dependent Protein Kinase ◽

Camp Dependent Protein Kinase ◽

N Terminus ◽

Dependent Protein

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A Stable α-Helical Domain at the N Terminus of the RIα Subunits of cAMP-dependent Protein Kinase Is a Novel Dimerization/Docking Motif

Journal of Biological Chemistry ◽

10.1074/jbc.272.45.28431 ◽

1997 ◽

Vol 272 (45) ◽

pp. 28431-28437 ◽

Cited By ~ 34

Author(s):

Darryl A. León ◽

Friedrich W. Herberg ◽

Poopak Banky ◽

Susan S. Taylor

Keyword(s):

Protein Kinase ◽

Dependent Protein Kinase ◽

Helical Domain ◽

Camp Dependent Protein Kinase ◽

N Terminus ◽

Dependent Protein

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