Inhibition of sarcoplasmic reticulum calcium pump by monoclonal antibodies

1987 ◽  
Vol 15 (3) ◽  
pp. 464-465 ◽  
Author(s):  
J. MALCOLM EAST ◽  
JOHN COLYER ◽  
ANTHONY G. LEE
Keyword(s):  
Monoclonal Antibodies ◽  
Sarcoplasmic Reticulum ◽  
Calcium Pump ◽  
Sarcoplasmic Reticulum Calcium

Invariance of Stoichiometry of the Sarcoplasmic Reticulum Calcium Pump at Physiological Calcium Concentrations – a Reevaluation

1985 ◽  
Vol 40 (7-8) ◽  
pp. 571-575 ◽  
Author(s):  
Wilhelm Hasselbach ◽  
Andrea Migala
Keyword(s):  
Sarcoplasmic Reticulum ◽  
Calcium Level ◽  
Calcium Concentration ◽  
Calcium Uptake ◽  
Atp Hydrolysis ◽  
Calcium Pump ◽  
Oxalate Precipitation ◽  
Sarcoplasmic Reticulum Calcium ◽  
Internal Calcium ◽  
External Calcium

Abstract The decline of the transport ratio of the sarcoplasmic calcium pump observed in a recent study (A. results from the retardation of calcium oxalate precipitation at low calcium/protein ratios. The prevailing high internal calcium level supports a rapid calcium backflux and a compensatory ATP hydrolysis during net calcium uptake which reduces the transport ratio. Yet, the determined calcium back­ flux does not fully account for the decline of the transport ratio. A supposed modulation of the stoichiometry of the pump by external calcium (0.1 μм) is at variance with results of previous studies showing a constant transport ratio of two in the same calcium concentration range.

scholarly journals Kinetic characterization of the normal and procaine-perturbed reaction cycles of the sarcoplasmic reticulum calcium pump

1991 ◽  
Vol 202 (2) ◽  
pp. 559-567 ◽  
Author(s):  
Fernando HENAO ◽  
Beatrice FORESTA ◽  
Stephane ORLOWSKI ◽  
Ana CUENDA ◽  
Carlos GUTIERREZ-MERINO ◽  
...  
Keyword(s):  
Sarcoplasmic Reticulum ◽  
Calcium Pump ◽  
Kinetic Characterization ◽  
Reaction Cycles ◽  
Sarcoplasmic Reticulum Calcium
Sign in / Sign up

Export Citation Format

Share Document