Quantification of the control exerted by different steps during citrulline synthesis in isolated rat liver mitochondria

1983 ◽  
Vol 11 (1) ◽  
pp. 89-90 ◽  
Author(s):  
RONALD J. A. WANDERS ◽  
ALFRED J. MEIJER ◽  
CARLO M. VAN ROERMUND ◽  
ALBERT K. GROEN ◽  
COR LOF ◽  
...  
Keyword(s):  
Rat Liver ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria ◽  
Isolated Rat Liver ◽  
Citrulline Synthesis ◽  
Isolated Rat

scholarly journals Sub-micromolar concentrations of extramitochondrial Ca2+ stimulate the rate of citrulline synthesis by rat liver mitochondria

1989 ◽  
Vol 257 (1) ◽  
pp. 285-288 ◽  
Author(s):  
J D Johnston ◽  
M D Brand
Keyword(s):  
Rat Liver ◽  
Urea Cycle ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria ◽  
Hormonal Stimulation ◽  
Isolated Rat Liver ◽  
Citrulline Synthesis ◽  
Isolated Rat ◽  
Stimulation Of

1. In the presence of physiological concentrations of Na+ and Mg2+, the rate of citrulline synthesis by isolated rat liver mitochondria respiring on a range of substrates was stimulated by up to 60% when the extramitochondrial Ca2+ concentration was raised from 130 pM to 770 nM. 2. Our findings suggest that hormonal stimulation of the urea cycle may be mediated by Ca2+.

Sign in / Sign up

Export Citation Format

Share Document