Structure and Function of the Receptor for Immunoglobulin E (IgE) on Mast Cells

1981 ◽  
Vol 9 (2) ◽  
pp. 60P-60P
Author(s):  
H. Metzger ◽  
C. Fewtrell ◽  
A. Goetze ◽  
D. Holowka ◽  
J. Kanellopoulos
Keyword(s):  
Mast Cells ◽  
Immunoglobulin E ◽  
Structure And Function ◽  
And Function

Analysis of the structure and function of the receptor for immunoglobulin E

1984 ◽  
Vol 21 (12) ◽  
pp. 1167-1173 ◽  
Author(s):  
Henry Metzger ◽  
Benjamin Rivnay ◽  
Marianne Henkart ◽  
Baruch Kanner ◽  
Jean-Pierre Kinet ◽  
...  
Keyword(s):  
Immunoglobulin E ◽  
Structure And Function ◽  
And Function

scholarly journals ELECTRON MICROSCOPY OF THE TISSUE MAST CELL

1957 ◽  
Vol 3 (1) ◽  
pp. 9-14 ◽  
Author(s):  
Douglas E. Smith ◽  
Yevette S. Lewis
Keyword(s):  
Electron Microscopy ◽  
Endoplasmic Reticulum ◽  
Mast Cells ◽  
Internal Structure ◽  
Toluidine Blue ◽  
Structure And Function ◽  
Protamine Sulfate ◽  
Tissue Mast Cell ◽  
And Function ◽  
Double Nature

Electron microscopy was carried out on sections through tissue mast cells from the peritoneal fluid of rats and hamsters, either untreated, x-irradiated, or injected with toluidine blue, protamine sulfate, or stilbamidine. Mast cells from untreated animals have large nuclei and are filled with densely packed, cytoplasmic granules. The latter possess a distinct boundary and an internal structure which is reticular or vacuolar in nature. Between the granules are found elongate mitochondria and endoplasmic reticulum. Mitochondria often appear also in groups in granule-free areas adjacent to the nucleus. Nuclear and cell membranes of an apparent double nature are found. After treatment with toluidine blue, protamine sulfate, and stilbamidine the granules are surrounded by clear areas and are widely separated from one another; the endoplasmic reticulum is more conspicuous. The internal structure of the granule is unchanged. In the mast cells from x-irradiated animals there is an apparent coalescence of granules which is attented by a loss of intragranular structure. The findings are discussed in relation to other work on the structure and function of mast cells.

Structure and function of neural networks in the retina

1988 ◽  
Vol 46 ◽  
pp. 26-27
Author(s):  
Peter Sterling
Keyword(s):  
Ganglion Cells ◽  
Three Dimensional ◽  
Structure And Function ◽  
Synaptic Connections ◽  
Visual Axis ◽  
One Dimensional ◽  
Cat Retina ◽  
Ultrathin Sections ◽  
And Function ◽  
Insight Into

The synaptic connections in cat retina that link photoreceptors to ganglion cells have been analyzed quantitatively. Our approach has been to prepare serial, ultrathin sections and photograph en montage at low magnification (˜2000X) in the electron microscope. Six series, 100-300 sections long, have been prepared over the last decade. They derive from different cats but always from the same region of retina, about one degree from the center of the visual axis. The material has been analyzed by reconstructing adjacent neurons in each array and then identifying systematically the synaptic connections between arrays. Most reconstructions were done manually by tracing the outlines of processes in successive sections onto acetate sheets aligned on a cartoonist's jig. The tracings were then digitized, stacked by computer, and printed with the hidden lines removed. The results have provided rather than the usual one-dimensional account of pathways, a three-dimensional account of circuits. From this has emerged insight into the functional architecture.

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