Partial Reactions of the Calcium-Transport System of the Sarcoplasmic Reticulum

1979 ◽  
Vol 7 (4) ◽  
pp. 757-759
Author(s):  
P. FINBARR DUGGAN
1986 ◽  
Vol 41 (5-6) ◽  
pp. 647-651 ◽  
Author(s):  
Martina Ungeheuer ◽  
Andrea Migala ◽  
Wilhelm Hasselbach

The blockage of all thiol residues accessible to the mercurial mersalyl in the sarcoplasmic reticulum membranes resulting in complete inactivation of the membranes’ calcium transport system does interfere neither with caffeine- nor calcium-induced calcium release from actively loaded membrane vesicles.


1971 ◽  
Vol 57 (1) ◽  
pp. 64-70 ◽  
Author(s):  
A. Weber

The outflux of calcium from vesicles of sarcoplasmic reticulum is controlled by the concentration of ionized calcium in the medium. In a calcium-free medium calcium outflux is at a minimum provided ATP and Mg are present. If they are removed calcium outflux becomes rapid and has a rate constant similar to that of outflux during steady-state 40Ca-45Ca exchange with saturating calcium concentrations in the medium. In order to maintain the low permeability state of the membrane only the presence but not the continued hydrolysis of ATP is necessary.


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