scholarly journals Bioinformatics analysis and genetic polymorphisms in genomic region of the bovine SH2B2 gene and their associations with molecular breeding for body size traits in qinchuan beef cattle

2020 ◽  
Vol 40 (3) ◽  
Author(s):  
Sayed Haidar Abbas Raza ◽  
Rajwali Khan ◽  
Linsheng Gui ◽  
Nicola M. Schreurs ◽  
Xiaoyu Wang ◽  
...  
Keyword(s):  
Body Weight ◽  
Beef Cattle ◽  
Body Length ◽  
Genomic Region ◽  
Janus Kinase ◽  
Chest Circumference ◽  
Cytokine Signaling ◽  
Nucleotide Polymorphisms ◽  
Qinchuan Cattle ◽  
Body Measurement Traits

Abstract The Src homology 2 B 2 (SH2B2) gene regulate energy balance and body weight at least partially by enhancing Janus kinase-2 (JAK2)-mediated cytokine signaling, including leptin and/or GH signaling. Leptin is an adipose hormone that controls body weight. The objective of the present study is to evaluate the association between body measurement traits and SH2B2 gene polymorphisms as responsible mutations. For this purpose, we selected four single-nucleotide polymorphisms (SNPs) in SH2B2 gene, including two in intron 5 (g.20545A>G, and g.20570G>A, one synonymous SNP g.20693T>C, in exon 6 and one in intron 8 (g.24070C>A, and genotyped them in Qinchuan cattle. SNPs in sample populations were in medium polymorphism level (0.250<PIC<0.500). Association study indicated that the g.20570G>A, g.20693T>C, and g.24070C>A, significantly (P < 0.05) associated with body length (BL) and chest circumference (CC) in Qinchuan cattle. In addition, H4H3 and H5H5 diplotype had highly significantly (P < 0.01) greater body length (BL), rump length (RL), and chest circumference (CC) than H4H2. Our investigation will not only extend the spectrum of genetic variation of bovine SH2B2 gene, but also provide useful information for the marker assisted selection in beef cattle breeding program.

131 Genetic variants and haplotype combination in the bovine SH2B2 gene and their associations with molecular breeding for body size traits in Qinchuan cattle (Bos taurus)

2020 ◽  
Vol 32 (2) ◽  
pp. 192
Author(s):  
S. H. A. Raza ◽  
L. Zan
Keyword(s):  
Body Weight ◽  
Bos Taurus ◽  
Janus Kinase ◽  
Nucleotide Polymorphisms ◽  
Qinchuan Cattle ◽  
Single Nucleotide ◽  
Body Measurement Traits ◽  
Src Homology ◽  
Selected Traits ◽  
Polymorphism Level

The Src homology 2B 2 (SH2B2) gene regulates energy balance and body weight at least partially by enhancing Janus kinase-2 (JAK2)-mediated cytokine signalling, including leptin or GH signalling. Leptin is an adipose hormone that controls body weight. The objective of the current study was to evaluate the association between body measurement traits and SH2B2 gene polymorphisms. For this purpose, we selected four single-nucleotide polymorphisms (SNPs) in the SH2B2 gene, including two in intron 5 (A20545G and G20570A), one synonymous SNP (T20693C) in exon 6, and one in intron 8 (C24070A), and genotyped these through DNA sequencing in Qinchuan cattle. The general linear model (GLM) in SPSS 20.0 software (SPSS Inc.) was used for the association analysis between SNPs and selected traits of carcass quality. The SNPs in sample populations were in medium polymorphism level (0.250<pic<0.500). This association study indicated that the G20570A, T20693C, and C24070A were significantly (P<0.05) associated with body length (BL) and chest circumference (CC) in Qinchuan cattle. In addition, the H4H3 and H5H5 diplotype were associated with significantly (P=0.01) greater BL and rump length than was H4H2. Our investigation will not only extend understanding of genetic variations in the bovine SH2B2 gene but also provide useful information for marker-assisted selection in beef cattle breeding programs.

scholarly journals REKONDISI BEBERAPA UKURAN TUBUH TERNAK SAPI PERAH FRIESS HOLLAND DI BALAI PENGEMBANGAN BIBIT DAN PAKAN TERNAK TAMPUSU

ZOOTEC ◽  
2019 ◽  
Vol 39 (1) ◽  
pp. 165
Author(s):  
Renaldo J. Maluhima ◽  
J.H. Manopo ◽  
A. Lomboan ◽  
S.H. Turangan
Keyword(s):  
Body Weight ◽  
Dairy Cattle ◽  
Seed Development ◽  
Body Length ◽  
Animal Feed ◽  
Chest Circumference ◽  
Descriptive Research ◽  
Body Sizes ◽  
Development Center ◽  
Average Body

COMPENSATORY CONDITION OF SEVERAL MEASURES IN FRIESS HOLLAND DAIRY CATTLE AT TAMPUSU ANIMAL FEED AND SEED DEVELOPMENT CENTER. This study was conducted to assess the compensatory condition of some body sizes of Friess Holland Dairy Cattle at Tampusu Animal Feed and Seed Development Center. Animals used in this study were 23 Friesian Fries Holland (FH) dairy cattle at aged of 7 months to 7 years old using a comparative descriptive research method by comparing the same variables for different samples and using the t-test. Research was done by measuring body weight, chest circumference, shoulder’s height and body length. The maintenance of animals was using a double cage head to head. Feeds given were using forages of 10% / head / day from body weight. Concentrate was fed about 2 kg / head / day. Dairy cows in Tampusu have an average body weight of 401.533 ± 39.47 Kg with a varince coefficient value of  9.8%, an average chest circumference of 174.12 ± 11.15 cm with a varience coefficient value of 6.4%, average shoulder height 136.47 ± 9.16 cm with a variance coefficient value of 6.7%, average body length 139.39 ± 9.56 vm with a variance coefficient of 6.8%. Based on these results, the compensatory condition friess holland dairy cattle at tampusu animal feed and seed development center was increase   body weight of 11.6%, chest circumference 6.28% and shoulder height of 6.65%. Keywords: Compensatory condition, body measurements, Friess Holland Dairy Cattle

scholarly journals Identification of MC4R gene and its association with body weight and body size in Kebumen Ongole Grade cattle

2018 ◽  
Vol 43 (2) ◽  
pp. 87
Author(s):  
D. Maharani ◽  
A. Fathoni ◽  
S. Sumadi ◽  
T. Hartatik ◽  
M. Khusnudin
Keyword(s):  
Body Length ◽  
Growth Traits ◽  
Average Daily Gain ◽  
Pcr Amplification ◽  
Growth Trait ◽  
Chest Circumference ◽  
Nucleotide Polymorphisms ◽  
Chi Square ◽  
Mc4r Gene ◽  
Genotype Frequencies

MC4R gene is known as an important candidate gene for the growth trait. The purpose of this research was to identify the MC4R gene in Kebumen Ongole grade cattle and examine its association with growth traits. Data of birth weight (BW), weaning weight (WW), birth body length (BBL), birth chest circumference (BCC), birth shoulder height (BSH), weaning body length (WBL), weaning chest circumference(WCC), weaning shoulder height (WSH) and average daily gain (ADG) were collected and used for analysis of MC4R gene. Sixty blood samples were collected for DNA isolation and PCR amplification. The single nucleotide polymorphisms (SNP) g.1133 C>G was used for genotyping by using PCR-RFLP methods. The frequenciy of G allele (0.59) was greater than C allele (0.41). The highest genotype frequencies have been detected in CG heterozygote animals (0.52) followed by GG (0.33) and CC (0.15) in homozygote animals. The results of Pearson ‘s Chi-square test indicated that the population was not deviate (P>0.05) from the Hardy-Weinberg equilibrium (HWE). The SNP g. 1133 C>G of MC4R gene indicated affecting high birth body length with GG genotype (P<0.05). In conclusion, the SNP g. 1133 C>G may can be a marker for birth body length of calf selection.

scholarly journals Morphometrics and genetic diversity of Tegal, Magelang and their crossbred ducks based on Cytochrome b gene

2018 ◽  
Vol 43 (1) ◽  
pp. 9
Author(s):  
H. Henrik ◽  
D. Purwantini ◽  
I. Ismoyowati
Keyword(s):  
Genetic Diversity ◽  
Body Weight ◽  
Genetic Distance ◽  
Cytochrome B ◽  
Body Length ◽  
The Body ◽  
Chest Circumference ◽  
Neck Length ◽  
Significant Difference ◽  
Cyt B Gene

This experiment was conducted to study the morphometric and genetic diversity of Tegal, Magelang, and their crossbred ducks. Each ten female about twenty weeks old ducks from Tegal, Magelang, Gallang, and Maggal ducks, respectively, were used as the group materialss. The body weight, chest circumference, body length, shank length, neck length, and pubis width were recorded and tested by analysis of variance of one way classification as the morphometric characteristics. Polymorphism of cytochrome b (cyt b) gene on mitochondrial DNA (mtDNA) was analyzed by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). Genetic distance was analyzed based on value of heterozygosity, whereas the phylogeny tree was reconstructed using MEGA6 software. The results showed there were highly significant difference (P<0.01) on body weight, chest circumference, body length, and neck length between population, while shank and pubis width were not significant different. The genetic distance between Gallang and Maggal ducks (0.206) was higher than Tegal and Magelang ducks (0.169). It is concluded that the reciprocal crosses increased the morphometric and genetic diversity of Indonesian local duck population.

scholarly journals Hubungan Ukuran-Ukuran Tubuh Terhadap Bobot Badan Sapi Simmental Peranakan Ongole Jantan Pada Berbagai Kelompok Umur di Rumah Pemotongan Hewan Sapi Jagalan Surakarta

2017 ◽  
Vol 15 (1) ◽  
pp. 16
Author(s):  
Sofie Suliani ◽  
Ahmad Pramono ◽  
Joko Riyanto ◽  
Sigit Prastowo
Keyword(s):  
Body Weight ◽  
Body Size ◽  
Body Length ◽  
Strong Correlation ◽  
Chest Circumference ◽  
Carcass Weight ◽  
Dental Anatomy ◽  
Group 3 ◽  
R Value ◽  
Group 2

<p><em>This study aim to know the relationship between body size, body weight and carcass weight of male Simmental Ongole crossbred at various age. The study was conducted in Jagalan abattoir in Surakarta for 2 months from December 2016 untill Januari 2016. Ninety heads of male Simmental Ongole crossbred were grouped into 3 groups (each 30 heads) that are Group 1 (1,5-2 years old), Group 2 (2-3 years old) and Group 3 (3-3,5 years old) according to dental anatomy observation at the incisivus replacement. Body length and chest circumference were respectively observed then correlated with body weight and carcass weight. Result shows a strong correlation between body weight and carcass weight by r value 0.931. The correlation between body length with body weight, chest circumference with body weight of Group1, Group 2 and Group 3 also shows in similiar pattern, with r value 0.647, 0.787, 0.666, and 0.661, 0.851, 0.661 respectively. A strong correlation also expressed between body length with carcass weight and chest circumference with carcass weight in each of groups as shown by r value 0.638, 0.740, 0.551 and 0.572, 0.803, 0.603 respectively. It is conculded that body size, body weight and carcass weight of male Simmental Ongole crossbreed have strong correlation among others.</em></p>

scholarly journals MODERN SPECIFIC FEATURES OF THE PHYSICAL DEVELOPMENT OF SCHOOL STUDENTS OF YEKATERINBURG

2019 ◽  
Vol 98 (3) ◽  
pp. 301-307
Author(s):  
Liudmila L. Lipanova ◽  
A. S. Babikova ◽  
G. M. Nasybullina ◽  
O. S. Popova
Keyword(s):  
Body Weight ◽  
Body Length ◽  
Physical Development ◽  
Chest Circumference ◽  
Hand Strength ◽  
School Students ◽  
Large Cities ◽  
Lung Capacity ◽  
The City ◽  
Average Body

Introduction. An investigation aimed at studying the modern specific features of the physical development of children of school age of Yekaterinburg city was performed. Material and Methods. Somatic (body length, body weight, chest circumference) and physiometric (vital lung capacity, hand strength) physical development indices of 1378 school students of the city of Yekaterinburg aged from 8 to 16 years were surveyed and studied using the anthropomorphic measurement method (cross-sectional studies). The obtained results were compared with the equivalent physical development results collected from the children within the period between 1894 and 2000, as well as physical development data of school students residing in the large cities of the Russian Federation; Student’s t-test, regression analysis were used. Results. A decline in somatometric indices of the physical development (body length, weight, chest circumference) in all age and gender groups of school students was noted within the period between 1894 and 2017, but the decreased average values of the physiometric parameters, i.e. vital lung capacity, hand strength, were noted from 1985. The average body length and average body weight of school students of the city of Yekaterinburg are not significantly different or higher as compared to the peers residing in the large cities of the Russian Federation. In contrast to the regional physical development standards (as of 2000), each third school student has high or higher than average physical development indices: body length by 26.4%, body weight - 36%, chest circumference - 29.8%; a high incidence of low physiometric parameters was noted: low and lower than average indices of the vital lung capacity are characteristic to 35.1% of school students, hand strength - to 20.4% (right) and 22.9% (left) school students. Conclusion. The obtained results are indicative of the epoch-making changes in the physical development of children of the school age, as well as of certain regional distinguishing features, which may be associated with changes in the social and economic, environmental situation, and life style peculiarities of the modern school students.

scholarly journals Bafra Koyun ve Kuzularının Biyometrik Özelliklerinin İncelenmesi

2019 ◽  
Vol 7 (10) ◽  
pp. 1710
Author(s):  
Sezen Ocak Yetişgin
Keyword(s):  
Body Weight ◽  
Path Analysis ◽  
Correlation Coefficient ◽  
Body Length ◽  
Pearson Correlation ◽  
Live Weight ◽  
Chest Circumference ◽  
Pearson Correlation Coefficient ◽  
Weight Estimation

The aim of this study was to compare the effects of biometric properties of Bafra sheep and lambs such as chest depth, chest width, chest circumference, rump height, height at withers, body length and body weight. Relationships were determined by Pearson correlation coefficient and Path analysis. As a result, it has been shown that biometric properties of Bafra sheep and lambs provide different results on live weight estimation. In addition, the relationships between biometric properties were not similar (r = -0.16).

scholarly journals KARAKTERISTIK KUANTITATIF DAN KUALITATIF KAMBING DAN DOMBA SEBAGAI HEWAN QURBAN DI MITRA TANI FARM

2015 ◽  
Vol 39 (2) ◽  
pp. 84 ◽  
Author(s):  
Komariah (Komariah) ◽  
Dwi Joko Setyono ◽  
Aslimah (Aslimah)
Keyword(s):  
Body Weight ◽  
Body Length ◽  
The Body ◽  
Chest Circumference ◽  
Hair Color ◽  
Chi Square ◽  
Chi Square Test ◽  
Chest Girth ◽  
Average Body ◽  
Test Correlation

<p>The objective of the present study was to study the qualitative characteristics (wool color, horned) and the quantitative characteristics (body weight, chest circumference, body length, age) of sheep and goats for qurban in the Mitra Tani Farm; and the consumers preferences of choosing the sheep and goat required for ‘qurban’ event. In total eighty three Jawarandu goats; 16 Garut; 37 Thin-Tailed and 35 Fat-Tailed rams were observed to measure their body weight, chest circumference, body length, age, the present of horn and hair color. Qualitative data was obtained by interviewing the owner and consumers of MT Farm (30 trader and 30 consumers). The data was statistically analysis using, chi-square test, correlation test and T test. The results showed that the consumers from Jakarta, Depok and Tangerang significantly (P&lt;0.05) prefer goats than rams, while the consumers from Bogor, Yogyakarta and Bandung prefer rams than goats. The traders more consider the weight of the body (posture) and the price, while consumers more consider the finance budget. The average body weight of Jawarandu was 25.84±4.54 kg; Garut, Fat-Tailed and Thin-Tailed rams were 29.32±3.61, 28.45±5.54 and 28.44±4.65 kg respectively. The chest girth had higher correlation with body weight than body length. The percentage of goats and rams age were 60.56% (I0), 33.89% (I1) and 5.56% (I2). The dominant color of Jawarandu goat were brown (54.2%), black (26.51%) and white (19.28%). The color of Fat-Tailed rams wool more uniform than Thin-Tailed rams or Garut.</p><p><br />(Key words: Characteristics of Sheep and Goat, Mitra Tani Farm, Qurban)</p>

scholarly journals Korelasi Ukuran Tubuh terhadap Bobot Badan Sapi Aceh Umur Sapih dan Umur Satu Tahun

2018 ◽  
Vol 18 (2) ◽  
pp. 117-122
Author(s):  
Ikhsanuddin Ikhsanuddin ◽  
Veronica Margareta Ani Nurgiartiningsih ◽  
Kuswati Kuswati ◽  
Zainuddin Zainuddin
Keyword(s):  
Body Weight ◽  
Body Size ◽  
Regression Model ◽  
Body Length ◽  
Regression Equation ◽  
The Body ◽  
Chest Circumference ◽  
Weaning Weight ◽  
Weaning Age

ABSTRAK. Penelitian ini bertujuan untuk menghitung nilai korelasi antara bobot badan dengan ukuran tubuh serta mengestimasi bobot badan (BB) berdasarkan ukuran tubuh. Materi penelitian ini adalah 159 ekor sapi Aceh umur sapih dan umur satu tahun. Metode penelitian adalah studi kasus berdasarkan data bobot sapih dan bobot satu tahun beserta ukuran tubuh sapi Aceh. Hasil penelitian pada sapi Aceh umur sapih menunjukkan korelasi bobot badan dengan lingkar dada, panjang badan, dan tinggi pundak berturut-turut 0.65, 0,56 dan 0,64, sedangkan nilai determinasinya adalah 0,42, 0,30 dan 0,41. Model regresi untuk estimasi bobot badan umur sapih yaitu BB= -30,23 + 0,47LD + 0,13PB + 0,50TP. Untuk sapi Aceh umur satu tahun nilai korelasi bobot badan dengan lingkar dada, panjang badan, dan tinggi pundak berturut-turut 0.69, 0,58 dan 0,55, nilai determinasinya adalah 0,47, 0,34 dan 0,30. Persamaan garis regresi untuk sapi Aceh umur satu tahun yaitu BB = -44,96 + 0,72LD + 0,46PB + 0,24TP. Berdasarkan hasil analisis korelasi menunjukkan bahwa korelasi lingkar dada dengan bobot badan memiliki hubungan paling kuat dibandingkan dengan panjang badan dan tinggi pundak.  (Correlation between body size and body weight of Aceh Cattle at weaning and yearling age) ABSTRACT. This study aimed to evaluate the correlation between body weight and body size, as well to estimate body weight based on body size. A total of 159 Aceh cattle at weaning and yearling age were used in this study. The method used was a case study based on the data on weaning weight, yearling weight, and body size of Aceh cattle. The results showed that at the weaning age, the correlation values between body weight (BW) with chest circumference (CC), body length (BL), and shoulder height (SH) were 0.65, 0.56, and 0.64, respectively, while the determinant values were 0.42, 0.30, and 0.41, respectively. Regression model for estimating body weight at weaning age was BW = -30.23 + 0.47CC + 0.13BL + 0.50SH. At the yearling age, the correlation values of body weight with chest circumference, body length, and shoulder height were 0.69, 0.58, and 0.55, respectively, while the determinant values were 0.47, 0.34, and 0.30, respectively. The regression equation for yearling Aceh cattle was BW = -44.96 + 0.72CC + 0.46BL + 0.24SH. This study showed that the highest correlation was observed on the body weight with chest circumference compared to those with either body length or shoulder height.

scholarly journals Photoperiodic Regulation of Leptin Sensitivity in the Siberian Hamster, Phodopus sungorus, Is Reflected in Arcuate Nucleus SOCS-3 (Suppressor of Cytokine Signaling) Gene Expression

Endocrinology ◽  
2004 ◽  
Vol 145 (3) ◽  
pp. 1185-1193 ◽  
Author(s):  
Alexander Tups ◽  
Claire Ellis ◽  
Kim M. Moar ◽  
Tracy J. Logie ◽  
Clare L. Adam ◽  
...  
Keyword(s):  
Gene Expression ◽  
Body Weight ◽  
Arcuate Nucleus ◽  
Janus Kinase ◽  
Cytokine Signaling ◽  
Suppressor Of Cytokine Signaling ◽  
Serum Leptin ◽  
Siberian Hamster ◽  
Leptin Sensitivity ◽  
Socs3 Mrna

Abstract We present the first evidence that suppressor of cytokine signaling-3 (SOCS3), a protein inhibiting Janus kinase/signal transducer and activator of transcription (STAT) signaling distal of the leptin receptor, conveys seasonal changes in leptin sensitivity in the Siberian hamster. Food deprivation (48 h) reduced SOCS3 gene expression in hamsters acclimated to either long (LD) or short (SD) photoperiods, suggesting that leptin signals acute starvation regardless of photoperiod. However, SOCS3 mRNA levels were substantially lower in the hypothalamic arcuate nucleus of hamsters acclimated to SD than in those raised in LD. In juveniles raised in LD, a rapid increase in SOCS3 mRNA was observed within 4 d of weaning, which was completely prevented by transfer to SD on the day of weaning. The early increase in SOCS3 gene expression in juvenile hamsters in LD clearly preceded the establishment of different body weight trajectories in LD and SD. In adult LD hamsters, SOCS3 mRNA was maintained at an elevated level despite the chronic food restriction imposed to lower body weight and serum leptin to or even below SD levels. A single injection of leptin in SD hamsters elevated SOCS3 mRNA to LD levels, whereas leptin treatment had no effect on SOCS3 gene expression in LD hamsters. Our results suggest that the development of leptin resistance in LD-acclimated hamsters involves SOCS3-mediated suppression of leptin signaling in the arcuate nucleus. Increased SOCS3 expression in LD hamsters is independent of body fat and serum leptin levels, suggesting that the photoperiod is able to trigger the biannual reversible switch in leptin sensitivity.

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