scholarly journals Regulation of concentrations of mRNA for amylase, trypsinogen I and chymotrypsinogen B in rat pancreas by secretagogues

1986 ◽  
Vol 235 (1) ◽  
pp. 305-308 ◽  
Author(s):  
W Renaud ◽  
D Giorgi ◽  
J Iovanna ◽  
J C Dagorn
Keyword(s):  
Gene Expression ◽  
Translational Regulation ◽  
Protein Gene ◽  
Secretory Protein ◽  
Serine Proteinases ◽  
Rat Pancreas ◽  
Rna Transcripts ◽  
Specific Mrnas ◽  
Cloned Cdna

Regulation of pancreatic gene expression by the secretory stimulants cholecystokinin-pancreozymin, caerulein and pilocarpine was studied in the rat, by using cloned cDNA probes to quantify concentrations of specific mRNAs (amylase, trypsinogen I and chymotrypsinogen B). It is concluded that long-term pancreatic stimulation results in pre-translational regulation of secretory-protein gene expression, with a preferential accumulation of RNA transcripts encoding serine proteinases, compared with that for amylase.

Donor lung surfactant protein gene expression predicts early and long-term outcome

2005 ◽  
Vol 24 (2) ◽  
pp. S99-S100
Author(s):  
F. D’Ovidio ◽  
H. Kaneda ◽  
C. Andrade ◽  
M. Mura ◽  
H. Takahashi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Protein Gene ◽  
Lung Surfactant ◽  
Surfactant Protein ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Donor Lung ◽  
Lung Surfactant Protein

Regulation of prostatic genes: role of androgens and zinc in gene expression

1986 ◽  
Vol 64 (6) ◽  
pp. 601-607 ◽  
Author(s):  
R. J. Matusik ◽  
C. Kreis ◽  
P. McNicol ◽  
R. Sweetland ◽  
C. Mullin ◽  
...  
Keyword(s):  
Gene Expression ◽  
Signal Peptide ◽  
Prostate Gland ◽  
Male Rats ◽  
Castration Resistant ◽  
Gene Transcripts ◽  
Specific Mrnas ◽  
Steady State Levels ◽  
Cloned Cdna

Gene expression in the rat dorsolateral prostate gland has been studied using cloned cDNA probes to the most abundant expressed mRNAs. One cDNA clone (pM-40) corresponds to two closely homologous mRNAs of about 880 nucleotides which code for two proteins of 23 and 21 kilodaltons (kDa). At least the 23-kDa protein contains a signal peptide. Another clone (pRWB) corresponds to a 1550-nucleotide mRNA which codes for a 52-kDa protein which also contains a signal peptide. The steady-state levels of these specific mRNAs increase in the dorsolateral prostate with sexual maturation. In castrated mature male rats, the M-40 mRNAs are inducible either by androgens or zinc, while the RWB mRNA is only responsive to androgens. In situ cDNA–mRNA hybridization histochemistry has been used to study the localization of the M-40 and RWB gene transcripts. Both M-40 and RWB mRNAs are most abundant in the epithelium of the lateral tip of the dorsolateral prostate. Following castration, the RWB mRNA decreases, while the M-40 mRNAs continue to be expressed in isolated areas of the epithelium. These castration-resistant cells maintain normal morphology in the absence of androgens.

scholarly journals Regulation of secretory protein gene expression in Paramecium

2000 ◽  
Vol 267 (11) ◽  
pp. 3226-3234 ◽  
Author(s):  
Angélique Galvani ◽  
Linda Sperling
Keyword(s):  
Gene Expression ◽  
Protein Gene ◽  
Secretory Protein

Regulation of Clara cell secretory protein gene expression by the CCAAT-binding factor NF-Y

2007 ◽  
Vol 459 (1) ◽  
pp. 33-39 ◽  
Author(s):  
Adriana Acosta ◽  
Teresa Zariñán ◽  
Héctor Macías ◽  
Ana María Pasapera ◽  
Marco Allán Pérez-Solis ◽  
...  
Keyword(s):  
Gene Expression ◽  
Protein Gene ◽  
Secretory Protein ◽  
Clara Cell ◽  
Clara Cell Secretory Protein ◽  
Binding Factor

Interplay between Pur α and Egr-1 in the transcriptional regulation of amyloid precursor protein gene expression

2010 ◽  
Vol 34 (8) ◽  
pp. S27-S27
Author(s):  
Jianqi Cui ◽  
Xiuying Pei ◽  
Qian Zhang ◽  
Bassel E. Sawaya ◽  
Xiaohong Lu ◽  
...  
Keyword(s):  
Gene Expression ◽  
Transcriptional Regulation ◽  
Amyloid Precursor Protein ◽  
Protein Gene ◽  
Precursor Protein ◽  
Amyloid Precursor Protein Gene
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