scholarly journals Regulation of lipolysis during pregnancy and lactation in sheep. Response to noradrenaline and adenosine

1985 ◽  
Vol 230 (3) ◽  
pp. 651-656 ◽  
Author(s):  
R G Vernon ◽  
E Finley
Keyword(s):  
Adipose Tissue ◽  
Cell Volume ◽  
Milk Production ◽  
Early Lactation ◽  
Mean Cell Volume ◽  
Basal Rate ◽  
Adipose Tissue In Vitro ◽  
Pregnancy And Lactation ◽  
Adenosine Analogue

The effects of pregnancy and lactation on lipolysis in sheep adipose tissue in vitro were investigated. Neither pregnancy nor lactation altered the basal rate of lipolysis. The rate of noradrenaline-stimulated lipolysis was directly proportional to adipocyte mean cell volume. Lactation, but not pregnancy, increased the response to noradrenaline, but had no effect on the ED50 of noradrenaline. The adenosine analogue N6-phenylisopropyladenosine decreased the rate of lipolysis in the presence of noradrenaline; the effect was greater with adipose tissue from lactating than from control, unmated, sheep. Results are discussed in relation to the need of sheep to mobilize lipid during early lactation to support milk production.

scholarly journals Adenosine and the control of lipolysis in rat adipocytes during pregnancy and lactation

1983 ◽  
Vol 216 (1) ◽  
pp. 121-128 ◽  
Author(s):  
R G Vernon ◽  
E Finley ◽  
E Taylor
Keyword(s):  
Adipose Tissue ◽  
Cell Volume ◽  
Adenosine Deaminase ◽  
Stromal Cells ◽  
Male Rats ◽  
Fat Cells ◽  
Pregnant Rats ◽  
Mean Cell Volume ◽  
Pregnancy And Lactation ◽  
Adenosine Analogue

The rate of noradrenaline-stimulated lipolysis is lower in fat-cells from lactating than from pregnant rats; this difference is eliminated by the addition of adenosine deaminase [Aitchison, Clegg & Vernon (1982) Biochem. J. 202, 243-247]. The activity of 5′-nucleotidase, and hence the capacity of the cells to synthesize adenosine, was the same in fat-cells and also stromal cells of adipose tissue from pregnant, lactating and male rats. The response and sensitivity of fat-cells to the anti-lipolytic effects of adenosine were measured by incubating cells in the presence of noradrenaline, adenosine deaminase (to remove endogenous adenosine) and various concentrations of the adenosine analogue N6-phenylisopropyladenosine (PIA). PIA caused a greater inhibition of the rate of noradrenaline-stimulated lipolysis in adipocytes from lactating than from pregnant rats. The concentration of PIA required to inhibit by 50% the rate of noradrenaline-stimulated lipolysis fell from over 100 nM for fat-cells from pregnant rats to 30 nM for fat-cells from lactating rats. The decreased rate of noradrenaline-stimulated lipolysis during lactation was not due to the smaller mean cell volume of adipocytes during this state.

HORMONAL REGULATION OF GLUCOSE METABOLISM IN ADIPOSE TISSUE IN VITRO

1965 ◽  
Vol 131 (1 Adipose Tissu) ◽  
pp. 43-58 ◽  
Author(s):  
Bernard R. Landau ◽  
Joseph Katz ◽  
Glenn E. Bartsch ◽  
Lawrence W. White ◽  
Hollis R. Williams
Keyword(s):  
Adipose Tissue ◽  
Glucose Metabolism ◽  
Hormonal Regulation ◽  
Adipose Tissue In Vitro

Hepatocyte differentiation of mesenchymal stem cells from human adipose tissue in vitro promotes hepatic integration in vivo

Gut ◽  
2008 ◽  
Vol 58 (4) ◽  
pp. 570-581 ◽  
Author(s):  
H Aurich ◽  
M Sgodda ◽  
P Kaltwasser ◽  
M Vetter ◽  
A Weise ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Adipose Tissue ◽  
Human Adipose Tissue ◽  
Hepatocyte Differentiation ◽  
Adipose Tissue In Vitro

Sulfatide increases adiponectin and decreases TNF-α, IL-6, and IL-8 in human adipose tissue in vitro

2007 ◽  
Vol 263 (1-2) ◽  
pp. 142-148 ◽  
Author(s):  
Jens M. Bruun ◽  
Allan Roeske-Nielsen ◽  
Bjørn Richelsen ◽  
Pam Fredman ◽  
Karsten Buschard
Keyword(s):  
Adipose Tissue ◽  
Human Adipose Tissue ◽  
Adipose Tissue In Vitro ◽  
Tnf Α

Effects of hormones on cyclic AMP release from rat adipose tissue in vitro

FEBS Letters ◽  
1974 ◽  
Vol 49 (1) ◽  
pp. 65-69 ◽  
Author(s):  
P. Zumstein ◽  
J. Zapf ◽  
E.R. Froesch
Keyword(s):  
Adipose Tissue ◽  
Cyclic Amp ◽  
Adipose Tissue In Vitro ◽  
Rat Adipose Tissue
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