C/EBPβ (CCAAT/enhancer-binding protein β) mediates progesterone production through transcriptional regulation in co-operation with SF-1 (steroidogenic factor-1)

2014 ◽  
Vol 460 (3) ◽  
pp. 459-471 ◽  
Author(s):  
Tetsuya Mizutani ◽  
Yunfeng Ju ◽  
Yoshitaka Imamichi ◽  
Tsukasa Osaki ◽  
Takashi Yazawa ◽  
...  

CCAAT/enhancer-binding protein β (C/EBPβ) was identified as a component of the SF-1 nuclear complex. C/EBPβ regulates expression of progesterone production-related genes (STAR, CYP11A1 and HSD3B2) by co-operation with SF-1. Our findings reveal a novel molecular mechanism of progesterone production.

2008 ◽  
Vol 283 (14) ◽  
pp. 8788-8795 ◽  
Author(s):  
Liping Qiao ◽  
Chenhui Zou ◽  
Peng Shao ◽  
Jerome Schaack ◽  
Peter F. Johnson ◽  
...  

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