scholarly journals Self-association of bovine immunoglobulin G1

1979 ◽  
Vol 183 (2) ◽  
pp. 463-465 ◽  
Author(s):  
T K S Mukkur ◽  
G D Smith

The self-association properties of bovine serum immunoglobulin G1 and colostral immunoglobulin G1 (IgG1) in 0.32 M-NaCl/0.01 M-Tris/HCl, pH 8.0, were investigated by analysing sedimentation data according to a monomer-dimer association model. The self-association was characterized by an equilibrium constant of 5.3 × 10(4) +/- 3.5 × 10(4) M-1 for serum IgG1 and 1.6 × 10(3) +/- 0.69 × 10(3) M-1 for colostral IgG1. The removal of the Fc portion of IgG1 by pepsin digestion abolished its property of self-aggregation. At high total protein concentrations of serum IgG1, low concentrations of the ostensible trimer species were observed. However, no self-aggregation was evident when 0.14 M-NaCl/0.01 M-sodium phosphate. pH 6.0, was used as a solvent, thus confirming results published previously [Tewari & Mukkur (1975) Immunochemistry 12, 925–930].

2014 ◽  
Vol 16 (28) ◽  
pp. 14688-14698 ◽  
Author(s):  
Predrag V. Petrović ◽  
Stefan Grimme ◽  
Snežana D. Zarić ◽  
Michel Pfeffer ◽  
Jean-Pierre Djukic

The issue of self-aggregation of oxaliplatin in water as well as in the gas phase is investigated analytically and analyzed by state-of-the-art DFT-D methods.


2019 ◽  
Vol 20 (12) ◽  
pp. 2948 ◽  
Author(s):  
Werner E.G. Müller ◽  
Emad Tolba ◽  
Shunfeng Wang ◽  
Qiang Li ◽  
Meik Neufurth ◽  
...  

A new biomimetic strategy to im prove the self-healing properties of Portland cement is presented that is based on the application of the biogenic inorganic polymer polyphosphate (polyP), which is used as a cement admixture. The data show that synthetic linear polyp, with an average chain length of 40, as well as natural long-chain polyP isolated from soil bacteria, has the ability to support self-healing of this construction material. Furthermore, polyP, used as a water-soluble Na-salt, is subject to Na+/Ca2+ exchange by the Ca2+ from the cement, resulting in the formation of a water-rich coacervate when added to the cement surface, especially to the surface of bacteria-containing cement/concrete samples. The addition of polyP in low concentrations (<1% on weight basis for the solids) not only accelerated the hardening of cement/concrete but also the healing of microcracks present in the material. The results suggest that long-chain polyP is a promising additive that increases the self-healing capacity of cement by mimicking a bacteria-mediated natural mechanism.


2021 ◽  
pp. 116819
Author(s):  
Lourdes Pérez ◽  
Ramon Pons ◽  
Francisco Fábio Oliveira de Sousa ◽  
Maria del Carmen Morán ◽  
Anderson Ramos da Silva ◽  
...  

1991 ◽  
Vol 6 (4-6) ◽  
pp. 299-310 ◽  
Author(s):  
Y. Adachi ◽  
K. Nakanishi

Sign in / Sign up

Export Citation Format

Share Document