scholarly journals Inhibition by trioxalen (psoralen) plus near-ultraviolet light of the induction of ornithine decarboxylase in Chinese-hamster cells

1979 ◽  
Vol 183 (1) ◽  
pp. 179-180 ◽  
Author(s):  
Y M Heimer ◽  
E Riklis

Trioxalen (trimethylpsoralen) plus near-u.v. light, a potent inhibitor of DNA and RNA synthesis, inhibits the induction of ornithine decarboxylase in stationary-phase V79 fibroblasts. It does not affect the translation of pre-existing mRNA. The method, in view of its high degree of specificity and precise timing, is a better choice for inhibiting RNA synthesis than the commonly used chemical inhibitors and precursor analogues.

1981 ◽  
Vol 91 (4-5) ◽  
pp. 391-394 ◽  
Author(s):  
Nora Babudri ◽  
Bianca Pani ◽  
Sandra Venturini ◽  
Marisa Tamaro ◽  
Carlo Montibragadin ◽  
...  

1995 ◽  
Vol 20 (10) ◽  
pp. 431-434 ◽  
Author(s):  
Olga B. Chernova ◽  
Michail V. Chernov ◽  
Munna L. Agarwal ◽  
William R. Taylor ◽  
George R. Stark

Author(s):  
T.A. Craig-Cameron ◽  
D.I. Southern ◽  
P.E. Pell

1971 ◽  
Vol 17 (4) ◽  
pp. 461-466 ◽  
Author(s):  
Hiroko Watanabe ◽  
Mamoru Watanabe

Infection of Escherichia coli by R23 results in a marked inhibition of rRNA synthesis. Both 16 S and 23 S RNA are inhibited with maximal inhibition occurring at 30 min. Inhibition of 4 S RNA is not as profound. DNA synthesis is also inhibited after R23 infection although infected cells continue to divide for about one generation (45–60 min) after infection.


Nature ◽  
1965 ◽  
Vol 205 (4976) ◽  
pp. 1131-1133 ◽  
Author(s):  
A. KRISHNAKUMARAN ◽  
H. OBERLANDER ◽  
H. A. SCHNEIDERMAN

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