scholarly journals The steady-state kinetics of isotope exchange at equilibrium: one substrate–one product enzymic mechanisms where two molecules of substrate or product are bound to an enzyme molecule (Short Communication)

1974 ◽  
Vol 143 (3) ◽  
pp. 783-784
Author(s):  
Ivan G. Darvey
Keyword(s):  
Steady State ◽  
Isotope Exchange ◽  
Short Communication ◽  
Enzyme Molecule ◽  
First Order ◽  
Steady State Kinetics ◽  
The One ◽  
Kinetics Of

The conclusion that the steady-state kinetics of isotope exchange at equilibrium do not show first-order behaviour for some one substrate–one product enzymic mechanisms in which two molecules of substrate or product can be combined with an enzyme molecule at the one time was shown to be erroneous.

scholarly journals The steady-state kinetics of isotope exchange for one substrate–one product enzymic reactions

1973 ◽  
Vol 135 (4) ◽  
pp. 861-866 ◽  
Author(s):  
Ivan G. Darvey
Keyword(s):  
Steady State ◽  
Isotope Exchange ◽  
Kinetic Equations ◽  
Enzyme Reaction ◽  
Radioactive Material ◽  
First Order ◽  
Steady State Kinetics ◽  
The One ◽  
Allosteric Mechanisms ◽  
Kinetics Of

Steady-state kinetic equations for isotope exchange are derived for a number of one substrate–one product enzymic mechanisms in which two molecules of substrate or product can be combined with an enzyme molecule at the one time (e.g. allosteric mechanisms). The usual assumption, that the radioactive material is distributed among the substrate and product components according to a first-order law, is not valid. One can recognize whether isotope-exchange kinetics of an enzyme reaction follows first-order behaviour by using various initial concentrations of the labelled substance added to a mixture.

scholarly journals Kinetics of Biofilm Detachment

1992 ◽  
Vol 26 (9-11) ◽  
pp. 1995-1998 ◽  
Author(s):  
B. M. Peyton ◽  
W. G. Characklis
Keyword(s):  
Steady State ◽  
Utilization Rate ◽  
Carbon Utilization ◽  
Biofilm Thickness ◽  
First Order ◽  
Detachment Rate ◽  
Biofilm Detachment ◽  
Biofilm Modeling ◽  
Kinetics Of ◽  
Sensitive Variable

In predictive biofilm modeling, the detachment rate coefficient may be the most sensitive variable affecting both the predicted rate and the extent of biofilm accumulation. At steady state the detachment rate must be equal to the net growth rate in the biofilm. In systems where organic carbon is growth-limiting, the substrate carbon utilization rate determines the net biomass production rate and, therefore, the steady state biomass detachment rate. Detachment rates, first order with biofilm thickness, fit the experimental data well, but are not predictive since the coefficients must be determined experimentally.

Steady-state kinetics of valproic acid in epileptic patients

1978 ◽  
Vol 24 (3) ◽  
pp. 324-332 ◽  
Author(s):  
J. Bruni ◽  
B. J. Wilder ◽  
L. J. Willmore ◽  
R. J. Perchalski ◽  
H. J. Villarreal
Keyword(s):  
Valproic Acid ◽  
Steady State ◽  
Steady State Kinetics ◽  
Epileptic Patients ◽  
Kinetics Of

Steady-state kinetics of bezafibrate retard in hyperlipidemic geriatric patients

1988 ◽  
Vol 66 (6) ◽  
pp. 250-256 ◽  
Author(s):  
G. Neugebauer ◽  
D. Platt ◽  
T. Vömel ◽  
W. Lösch
Keyword(s):  
Steady State ◽  
Geriatric Patients ◽  
Steady State Kinetics ◽  
Kinetics Of
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