scholarly journals Microbial metabolism of C1 and C2 compounds. The role of acetate during growth of Pseudomonas AM1 on C1 compounds, ethanol and β-hydroxybutyrate

1973 ◽  
Vol 132 (4) ◽  
pp. 797-801 ◽  
Author(s):  
Patricia M. Dunstan ◽  
C. Anthony
Keyword(s):  
Microbial Metabolism ◽  
The Novel ◽  
Short Term ◽  
Glyoxylate Bypass

Pseudomonas AM1 grows on β-hydroxybutyrate and methanol at similar rates. β-Hydroxybutyrate is not metabolized by way of the glyoxylate bypass, but is assimilated by the novel route (with acetate as an intermediate) that operates during growth of this organism on ethanol. Evidence from short-term labelling experiments indicates that acetate, which is a possible intermediate in the assimilation of C1 compounds, is rapidly metabolized to glycine during growth of Pseudomonas AM1 on methanol.

scholarly journals Microbial metabolism of C1 and C2 compounds. The involvement of glycollate in the metabolism of ethanol and of acetate by Pseudomonas AM1

1972 ◽  
Vol 128 (1) ◽  
pp. 99-106 ◽  
Author(s):  
Patricia M. Dunstan ◽  
C. Anthony ◽  
W. T. Drabble
Keyword(s):  
Alcohol Dehydrogenase ◽  
Generation Time ◽  
Isocitrate Lyase ◽  
Microbial Metabolism ◽  
Malate Synthase ◽  
Short Term ◽  
Glyoxylate Bypass ◽  
Incubation Experiments

Pseudomonas AM1 grows on ethanol with a mean generation time of about 10h. A single alcohol dehydrogenase is responsible for oxidation of both methanol and ethanol. It is proposed that the glyoxylate bypass does not operate in Pseudomonas AM1 during growth on ethanol. Although malate synthase is present in extracts of ethanol-grown Pseudomonas AM1, the activity of isocitrate lyase is negligible. Short-term incubation experiments with [14C]ethanol and [14C]acetate indicate that a novel pathway operates during growth of Pseudomonas AM1 on ethanol. Glycollate, glyoxylate and malate are probably intermediates in this pathway.

scholarly journals The Mesoscale Predictability Experiment (MPEX)

2015 ◽  
Vol 96 (12) ◽  
pp. 2127-2149 ◽  
Author(s):  
Morris L. Weisman ◽  
Robert J. Trapp ◽  
Glen S. Romine ◽  
Chris Davis ◽  
Ryan Torn ◽  
...  
Keyword(s):  
Wide Spectrum ◽  
Weather Prediction ◽  
Early Morning ◽  
Basic Question ◽  
The Novel ◽  
Short Term ◽  
Convective Storms ◽  
Central United States ◽  
Convective Scale

Abstract The Mesoscale Predictability Experiment (MPEX) was conducted from 15 May to 15 June 2013 in the central United States. MPEX was motivated by the basic question of whether experimental, subsynoptic observations can extend convective-scale predictability and otherwise enhance skill in short-term regional numerical weather prediction. Observational tools for MPEX included the National Science Foundation (NSF)–National Center for Atmospheric Research (NCAR) Gulfstream V aircraft (GV), which featured the Airborne Vertical Atmospheric Profiling System mini-dropsonde system and a microwave temperature-profiling (MTP) system as well as several ground-based mobile upsonde systems. Basic operations involved two missions per day: an early morning mission with the GV, well upstream of anticipated convective storms, and an afternoon and early evening mission with the mobile sounding units to sample the initiation and upscale feedbacks of the convection. A total of 18 intensive observing periods (IOPs) were completed during the field phase, representing a wide spectrum of synoptic regimes and convective events, including several major severe weather and/or tornado outbreak days. The novel observational strategy employed during MPEX is documented herein, as is the unique role of the ensemble modeling efforts—which included an ensemble sensitivity analysis—to both guide the observational strategies and help address the potential impacts of such enhanced observations on short-term convective forecasting. Preliminary results of retrospective data assimilation experiments are discussed, as are data analyses showing upscale convective feedbacks.

scholarly journals Diabetes and baseline glucose are associated with inflammation, left ventricular function and short- and long-term outcome in acute coronary syndromes: role of the novel biomarker Cyr 61

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Patric Winzap ◽  
Allan Davies ◽  
Roland Klingenberg ◽  
Slayman Obeid ◽  
Marco Roffi ◽  
...  
Keyword(s):  
Acute Coronary Syndromes ◽  
Left Ventricular ◽  
The Novel ◽  
Short Term ◽  
Coronary Syndrome ◽  
History Of ◽  
Coronary Syndromes ◽  
Short And Long Term

Abstract Background Hyperglycemia in the setting of an acute coronary syndrome (ACS) impacts short term outcomes, but little is known about longer term effects. We therefore designed this study to firstly determine the association between hyperglycemia and short term and longer term outcomes in patients presenting with ACS and secondly evaluate the prognostic role of diabetes, body mass index (BMI) and the novel biomarker Cyr61 on outcomes. Methods The prospective Special Program University Medicine-Acute Coronary Syndrome (SPUM-ACS) cohort enrolled 2168 patients with ACS between December 2009 and October 2012, of which 2034 underwent PCI (93.8%). Patients were followed up for 12 months. Events were independently adjudicated by three experienced cardiologists. Participants were recruited from four tertiary hospitals in Switzerland: Zurich, Geneva, Lausanne and Bern. Participants presenting with acute coronary syndromes and who underwent coronary angiography were included in the analysis. Patients were grouped according to history of diabetes (or HbA1c greater than 6%), baseline blood sugar level (BSL; < 6, 6–11.1 and > 11.1 mmol/L) and body mass index (BMI). The primary outcome was major adverse cardiac events (MACE) which was a composite of myocardial infarction, stroke and all-cause death. Secondary outcomes included the individual components of the primary endpoint, revascularisations, bleeding events (BARC classification) and cerebrovascular events (ischaemic or haemorrhagic stroke or TIA). Results Patients with hyperglycemia, i.e. BSL ≥ 11.1 mmol/L, had higher levels of C-reactive protein (CRP), white blood cell count (WBC), creatinine kinase (CK), higher heart rates and lower left ventricular ejection fraction (LVEF) and increased N-terminal pro-brain natriuretic peptide. At 30 days and 12 months, those with BSL ≥ 11.1 mmol/L had more MACE and death compared to those with BSL < 6.0 mmol/L or 6.0–11.1 mmol/L (HR-ratio 4.78 and 6.6; p < 0.001). The novel biomarker Cyr61 strongly associated with high BSL and STEMI and was independently associated with 1 year outcomes (HR 2.22; 95% CI 1.33–3.72; Tertile 3 vs. Tertile 1). Conclusions and relevance In this large, prospective, independently adjudicated cohort of in all comers ACS patients undergoing PCI, both a history of diabetes and elevated entry glucose was associated with inflammation and increased risk of MACE both at short and long-term. The mediators might involve increased sympathetic activation, inflammation and ischemia as reflected by elevated Cyr61 levels leading to larger levels of troponin and lower LVEF. Trial registration Clinical Trial Registration Number: NCT01000701. Registered October 23, 2009

Role of affect in short-term memory for paired associates.

1968 ◽  
Vol 78 (3, Pt.1) ◽  
pp. 494-501 ◽  
Author(s):  
Calvin F. Nodine ◽  
James H. Korn
Keyword(s):  
Short Term Memory ◽  
Short Term ◽  
Term Memory ◽  
Paired Associates

ROLE OF THE NOVEL INTRODUCED PAN-INTESTINAL CAPSULE ENDOSCOPY SYSTEM IN CELIAC DISEASE

2019 ◽  
Author(s):  
F Foerster ◽  
K Mönkemüller ◽  
PR Galle ◽  
H Neumann
Keyword(s):  
Celiac Disease ◽  
Capsule Endoscopy ◽  
The Novel

Patterns: Rosamond Lehmann

2018 ◽  
Author(s):  
Vike Martina Plock
Keyword(s):  
Coming Of Age ◽  
Public Image ◽  
Market Forces ◽  
The Novel ◽  
Fashion Industry ◽  
To The Lighthouse ◽  
Fashion Magazines ◽  
Female Authorship ◽  
Rosamond Lehmann

This chapter analyzes the role of fashion as a discursive force in Rosamond Lehmann’s 1932 coming-of-age novel Invitation to the Waltz. Reading the novel alongside such fashion magazines as Vogue, it demonstrates Lehmann’s awareness that 1920s fashion, in spite of its carefully stylized public image as harbinger of originality, emphasized the importance of following preconceived (dress) patterns in the successful construction of modern feminine types. Invitation to the Waltz, it argues, opposes the production of patterned types and celebrates difference and disobedience in its stead. At the same time, the novel’s formal appearance is nonetheless dependent on the very same tenets it criticizes. On closer scrutiny, it is seen to reveal its resemblance to Virginia Woolf’s To the Lighthouse (1927). A tension between imitation and originality determines sartorial fashion choices. This chapter shows that female authorship in the inter-war period was subjected to the same market forces that controlled and sustained the organization of the fashion industry.

SARS-COV2 virus and Coronavirus disease (COVID-19)

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 977-982
Author(s):  
Mohamed J. Saadh ◽  
Bashar Haj Rashid M ◽  
Roa’a Matar ◽  
Sajeda Riyad Aldibs ◽  
Hala Sbaih ◽  
...  
Keyword(s):  
Close Contact ◽  
Antiviral Agents ◽  
Health Concern ◽  
The Novel ◽  
Global Public Health ◽  
Fatal Disease ◽  
Mild Disease ◽  
Life Threatening ◽  
Novel Coronavirus

SARS-COV2 virus causes Coronavirus disease (COVID-19) and represents the causative agent of a potentially fatal disease that is of great global public health concern. The novel coronavirus (2019) was discovered in 2019 in Wuhan, the market of the wet animal, China with viral pneumonia cases and is life-threatening. Today, WHO announces COVID-19 outbreak as a pandemic. COVID-19 is likely to be zoonotic. It is transmitted from bats as intermediary animals to human. Also, the virus is transmitted from human to human who is in close contact with others. The computerized tomographic chest scan is usually abnormal even in those with no symptoms or mild disease. Treatment is nearly supportive; the role of antiviral agents is yet to be established. The SARS-COV2 virus spreads faster than its two ancestors, the SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), but has lower fatality. In this article, we aimed to summarize the transmission, symptoms, pathogenesis, diagnosis, treatment, and vaccine to control the spread of this fatal disease.

THE ROLE OF ARTISTIC PSYCHOLOGY IN THE METAPHORICAL HARMONY OF MAN AND THE REALITY OF LIFE

2020 ◽  
Vol 2 (3) ◽  
pp. 19-23
Author(s):  
Shakhlo Botirova ◽  
Keyword(s):  
The Novel

In this article , in the novel “Rebellion and obedience” by Ulugbek Hamdam, the author analyzes the artistic psychological description of a person on the path of development in the center of an integral complex metaphorical system of being. The novel “Rebellion and obedience” is based onthe method of metaphorization of reality. In it, a personexperiences vertigo about who he is and what powerful being he possesses. The reason for this is a riot. After much agony, he obeys. Allegedly thus proves its existence. Finds answers to certain riddles

Le premier moment de l’art dans À la recherche du temps perdu de Marcel Proust – une « leçon d’idéalisme » ?

2020 ◽  
pp. 25-40
Author(s):  
Larisa Botnari
Keyword(s):  
Essential Role ◽  
Marcel Proust ◽  
The Self ◽  
Philosophy Of Art ◽  
The Novel ◽  
Philosophical Interpretation ◽  
German Philosopher ◽  
Lost Time ◽  
Aesthetic Thinking

Although very famous, some key moments of the novel In Search of Lost Time, such as those of the madeleine or the uneven pavement, often remain enigmatic for the reader. Our article attempts to formulate a possible philosophical interpretation of the narrator's experiences during these scenes, through a confrontation of the Proustian text with the ideas found in the System of Transcendental Idealism (1800) of the German philosopher F. W. J. Schelling. We thus try to highlight the essential role of the self in Marcel Proust's aesthetic thinking, by showing that the mysterious happiness felt by the narrator, and from which the project of creating a work of art is ultimately born, is similar to the experiences of pure self-consciousness evoked and analyzed by Schellingian philosophy of art.

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