Tiglicaciduria in propionicacidaemia
Tiglic acid, which has not previously been found in human body fluids, was recently detected in the urine of two patients with propionicacidaemia. These patients had a documented defect in the oxidation of propionate. A competition between acrylyl-CoA and tiglyl-CoA for crotonase could explain the accumulation of tiglic acid.
1958 ◽
Vol 10
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pp. 310-318
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2000 ◽
Vol 107
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pp. 181-190
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2021 ◽
Vol 21
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pp. 31-42
2013 ◽
Vol 5
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1981 ◽
Vol 85
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pp. 248