scholarly journals Acid glycosaminoglycans of elastic cartilage

1970 ◽  
Vol 118 (2) ◽  
pp. 25P-25P ◽  
Author(s):  
G C Gillard ◽  
F S Wusteman
Keyword(s):  
Elastic Cartilage ◽  
Acid Glycosaminoglycans

scholarly journals Cencentration and composition of serum acid glycosaminoglycans in horses

1996 ◽  
Vol 12 (4) ◽  
pp. 488-492
Author(s):  
A Calatroni ◽  
R Vinci ◽  
A Ferlazzo ◽  
A M Ferlazzo
Keyword(s):  
Acid Glycosaminoglycans

scholarly journals Ear wound healing in MRL/MpJ mice is associated with gut microbiome composition and is transferable to non-healer mice via microbiome transplantation

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0248322
Author(s):  
Cassandra Velasco ◽  
Christopher Dunn ◽  
Cassandra Sturdy ◽  
Vladislav Izda ◽  
Jake Martin ◽  
...  
Keyword(s):  
Tissue Regeneration ◽  
Gut Microbiome ◽  
Vehicle Control ◽  
Repair Capacity ◽  
16S Sequencing ◽  
Microbiome Composition ◽  
Sex Effects ◽  
Elastic Cartilage ◽  
Better Than ◽  
Hole Closure

Objective Adult elastic cartilage has limited repair capacity. MRL/MpJ (MRL) mice, by contrast, are capable of spontaneously healing ear punctures. This study was undertaken to characterize microbiome differences between healer and non-healer mice and to evaluate whether this healing phenotype can be transferred via gut microbiome transplantation. Methods We orally transplanted C57BL/6J (B6) mice with MRL/MpJ cecal contents at weaning and as adults (n = 57) and measured ear hole closure 4 weeks after a 2.0mm punch and compared to vehicle-transplanted MRL and B6 (n = 25) and B6-transplanted MRL (n = 20) mice. Sex effects, timing of transplant relative to earpunch, and transgenerational heritability were evaluated. In a subset (n = 58), cecal microbiomes were profiled by 16S sequencing and compared to ear hole closure. Microbial metagenomes were imputed using PICRUSt. Results Transplantation of B6 mice with MRL microbiota, either in weanlings or adults, improved ear hole closure. B6-vehicle mice healed ear hole punches poorly (0.25±0.03mm, mm ear hole healing 4 weeks after a 2mm ear hole punch [2.0mm—final ear hole size], mean±SEM), whereas MRL-vehicle mice healed well (1.4±0.1mm). MRL-transplanted B6 mice healed roughly three times as well as B6-vehicle mice, and half as well as MRL-vehicle mice (0.74±0.05mm, P = 6.9E-10 vs. B6-vehicle, P = 5.2E-12 vs. MRL-vehicle). Transplantation of MRL mice with B6 cecal material did not reduce MRL healing (B6-transplanted MRL 1.3±0.1 vs. MRL-vehicle 1.4±0.1, p = 0.36). Transplantation prior to ear punch was associated with the greatest ear hole closure. Offspring of transplanted mice healed significantly better than non-transplanted control mice (offspring:0.63±0.03mm, mean±SEM vs. B6-vehicle control:0.25±0.03mm, n = 39 offspring, P = 4.6E-11). Several microbiome clades were correlated with healing, including Firmicutes (R = 0.84, P = 8.0E-7), Lactobacillales (R = 0.65, P = 1.1E-3), and Verrucomicrobia (R = -0.80, P = 9.2E-6). Females of all groups tended to heal better than males (B6-vehicle P = 0.059, MRL-transplanted B6 P = 0.096, offspring of MRL-transplanted B6 P = 0.0038, B6-transplanted MRL P = 1.6E-6, MRL-vehicle P = 0.0031). Many clades characteristic of female mouse cecal microbiota vs. males were the same as clades characteristic of MRL and MRL-transplanted B6 mice vs. B6 controls, including including increases in Clostridia and reductions in Verrucomicrobia in female mice. Conclusion In this study, we found an association between the microbiome and tissue regeneration in MRL mice and demonstrate that this trait can be transferred to non-healer mice via microbiome transplantation. We identified several microbiome clades associated with healing.

ChemInform Abstract: Acid Glycosaminoglycans and Their Chemical Modification

ChemInform ◽  
2009 ◽  
Vol 40 (12) ◽  
Author(s):  
I. Yu. Ponedel'kina ◽  
E. S. Lukina ◽  
V. N. Odinokov
Keyword(s):  
Chemical Modification ◽  
Acid Glycosaminoglycans

Acid glycosaminoglycans of pig aorta

1967 ◽  
Vol 23 (5) ◽  
pp. 344-345 ◽  
Author(s):  
J. R. Dunstone
Keyword(s):  
Acid Glycosaminoglycans

Activation criteria for cutaneous hemangiomas

1982 ◽  
Vol 63 (1) ◽  
pp. 9-11
Author(s):  
A. A. Ryzvanov
Keyword(s):  
Hyaluronic Acid ◽  
Blood Vessels ◽  
Vascular Tumor ◽  
Biopsy Material ◽  
Activation Criteria ◽  
Acid Glycosaminoglycans

Abstract. Morphohistochemical results. Studies of biopsy material from 51 patients with skin hemangiomas of various localization showed that the earliest and most permanent sign of vascular tumor activation is the accumulation of unsulfated acid glycosaminoglycans, mainly hyaluronic acid, in the walls of blood vessels and the stroma of the tumor itself

Idiopathic Bilateral Auricular Ossificans: A Case Report and Review of the Literature

2004 ◽  
Vol 128 (12) ◽  
pp. 1432-1434 ◽  
Author(s):  
Whitney A. High ◽  
Matthew J. Larson ◽  
Mai P. Hoang
Keyword(s):  
Radiographic Examination ◽  
Ectopic Calcification ◽  
Rare Occurrence ◽  
Review Of The Literature ◽  
Routine Testing ◽  
Elastic Cartilage ◽  
Addison Disease ◽  
Pathologic Findings ◽  
History Of ◽  
The Right

Abstract Petrification of the auricle results in a rigid and immalleable ear. The etiology of such a finding is usually ectopic calcification. The condition has been associated with injurious processes, such as cold injury, and with various endocrinopathies, including Addison disease. In a significant number of cases, ossification occurs without knowledge of the precipitating cause or event. True auricular ossification is a rare occurrence, with only 12 histologically confirmed cases in the literature. We herein present the clinical and pathologic findings of another case. A 60-year-old man with diet-controlled diabetes presented with a 10-year history of slowly and insidiously stiffened auricles. He denied any precipitating historical events. Routine testing did not demonstrate systemic abnormalities. Radiographic examination revealed opacities consistent with bony structure in the auricles of the ears, with the right more prominent than the left. Histologic sampling demonstrated ossification with deposition of trabecular bone in proximity to normal elastic cartilage.

Acid glycosaminoglycans in fetal pig epidermis

1968 ◽  
Vol 165 (1) ◽  
pp. 182-184 ◽  
Author(s):  
J.Graham Smith ◽  
Eugene A. Davidson
Keyword(s):  
Fetal Pig ◽  
Acid Glycosaminoglycans
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