scholarly journals The release of adenosine triphosphate catabolites during the secretion of catecholamines by bovine adrenal medulla

1966 ◽  
Vol 101 (2) ◽  
pp. 536-541 ◽  
Author(s):  
P Banks
1966 ◽  
Vol 44 (6) ◽  
pp. 879-891 ◽  
Author(s):  
C. J. Toews

The intracellular distribution of the hexokinase of the adrenal medulla was studied. Most of the hexokinase was found, in about equal amounts, in the mitochondria and the nonparticulate cytoplasm. The amount of hexokinase associated with the mitochondria was shown to be dependent on the hexokinase concentration in the medium surrounding the mitochondria.The hexokinase of the adrenal medulla was shown to be noncompetitively inhibited by adenosine diphosphate (ADP) with respect to glucose and adenosine triphosphate (ATP). It was competitively inhibited with respect to glucose by mannose, fructose, and galactose. Glucose-6-phosphate (0.09 M) did not inhibit the hexokinase. The data on product inhibition and initial velocity analysis support the concept of an ordered sequential mechanism for adrenal-medulla hexokinase.


1993 ◽  
Vol 23 (4) ◽  
pp. 343-350 ◽  
Author(s):  
Jef Pinxteren ◽  
Marlene Jimenez Del Rio ◽  
Carlos Velez Pardo ◽  
Guy Ebinger ◽  
Georges Vauquelin ◽  
...  

1988 ◽  
Vol 263 (25) ◽  
pp. 12744-12750
Author(s):  
H Murofushi ◽  
A Ikai ◽  
K Okuhara ◽  
S Kotani ◽  
H Aizawa ◽  
...  

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