scholarly journals Studies on protein and nucleic acid metabolism in virus-infected mammalian cells. 5. The kinetics of synthesis of virus protein and of virus ribonucleic acid in Krebs II mouse-ascites-tumour cells infected with encephalomyocarditis virus

1962 ◽  
Vol 83 (3) ◽  
pp. 574-582 ◽  
Author(s):  
EM MARTIN ◽  
TS WORK
1962 ◽  
Vol 25 (2) ◽  
pp. 183-NP ◽  
Author(s):  
W. B. JOLLEY ◽  
W. E. MARTIN ◽  
J. W. BAMBERGER ◽  
L. W. STEARNS

SUMMARY Oestradiol-17β at a concentration of 3 × 10−3 m inhibits cleavage in sea urchin (Strongylocentrotus purpuratus) embryos. This inhibition is accompanied by a reduction in deoxyribonucleic acid (DNA) synthesis and little change in ribonucleic acid (RNA). The effects of oestradiol-17β upon the incorporation of glycine-1-14C and glycine-2-14C into the purines of DNA and RNA and the incorporation of glycine-2-14C into serine were studied. The incorporation of glycine-1-14C and glycine-2-14C into RNA was reduced, but the incorporation of glycine-2-14C into DNA was increased considerably over that of the controls. The incorporation of glycine-2-14C into serine was also accelerated by oestradiol. A possible explanation of the action of oestradiol-17β is offered. The moderate effect upon RNA is not surprising because there is little or no synthesis of this compound from the time of fertilization to blastulation under normal conditions.


1949 ◽  
Vol s3-90 (12) ◽  
pp. 401-409
Author(s):  
T. YAO

In the egg of Drosophila the distribution of sulphydryl and ribonucleic acid compounds has no apparent connexion with the dorso-ventral organization, contrary to the situation found in the amphibian egg. Histochemical evidence suggests that the nucleic acid metabolism of the Drosophila egg may be similar to that of the chick embryo. During embryogenesis the contraction of the germ band can be considered as an important morphogenetic stage which marks the beginning of the histo-differentiation of all larval structures.


1963 ◽  
Vol 9 (3) ◽  
pp. 337-341 ◽  
Author(s):  
MICHIO OISHI ◽  
SHIGERU KITAYAMA ◽  
HAJIME TAKAHASHI ◽  
BUNJI MARUO

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