scholarly journals Selective accumulation of tritium-labelled hexoestrol by the reproductive organs of immature female goats and sheep

1959 ◽  
Vol 72 (4) ◽  
pp. 673-682 ◽  
Author(s):  
R. F. Glascock ◽  
W. G. Hoekstra
Keyword(s):  
Reproductive Organs ◽  
Immature Female ◽  
Selective Accumulation

THE UPTAKE OF RADIOACTIVE ISOMERS OF A SYNTHETIC OESTROGEN IN VARIOUS ORGANS OF IMMATURE MICE

1966 ◽  
Vol 53 (1) ◽  
pp. 84-92 ◽  
Author(s):  
Lars Terenius
Keyword(s):  
Skeletal Muscle ◽  
Simultaneous Administration ◽  
Immature Female ◽  
Female Mice ◽  
Selective Accumulation

ABSTRACT The meso- and rac.isomers of hexoestrol were labelled with tritium and administered systemically into immature female mice. Following the injection of meso-hexoestrol. the concentration of radioactivity was 10—20 times higher in the uterus, vagina and liver than in the skeletal muscle for at least 15 hours. 1 and 4 hours following injection, most of the recovered radioactivity in the uterus and vagina appeared to be unchanged meso-hexoestrol. In the plasma, most of the radioactivity was more polar. The uptake of meso-hexoestrol in the uterus and vagina was depressed by simultaneous administration of carrier. Pretreatment with 17β-oestradiol also inhibited the uterine and vaginal uptake while pretreatment with 17α-oestradiol was less efficient. The uptake in the liver and skeletal muscle was not inhibited. Following the injection of rac.-hexoestrol, there was no selective accumulation of radioactivity in the uterus or vagina in relation to skeletal muscle. The liver content equalled that found following the injection of the meso-isomer.

scholarly journals Effect of Manganese Exposure on the Reproductive Organs in Immature Female Rats

2012 ◽  
Vol 16 (4) ◽  
pp. 295-300 ◽  
Author(s):  
Soo In Kim ◽  
Yeon Seok Jang ◽  
Seung Hee Han ◽  
Myeong Jin Choi ◽  
Eun Hye Go ◽  
...  
Keyword(s):  
Reproductive Organs ◽  
Female Rats ◽  
Immature Female ◽  
Manganese Exposure

scholarly journals Investigation of the estrogenic activity of Pueraria candollei variety mirifica extract on rats

2019 ◽  
Vol 8 (10) ◽  
pp. 2172
Author(s):  
Dao Thi Vui ◽  
Nguyen Thu Hang ◽  
Nguyen Quoc Huy ◽  
Bui Thanh Tung
Keyword(s):  
Estrogenic Activity ◽  
Reproductive Organs ◽  
Mature Female ◽  
Female Rats ◽  
Ovariectomized Rats ◽  
Serum Estradiol ◽  
Immature Female ◽  
Pueraria Candollei ◽  
Immature Rats ◽  
Estradiol Concentration

Background: Pueraria candollei variety mirifica (PM) has been widely used as ingredient in many rejuvenating products. In this study, we aimed to assess the estrogenic activity of PM extract grown in Vietnam.Methods: Estrogenic activity of PM extract was estimated on immature female rats by using uterotrophic method to measure the weight of the reproductive organs. Estrogenic activity of PM extract also was investigated in mature female ovariectomized rats by evaluating the vaginal cells growth, reproductive organs weight, serum estradiol concentration.Results: Our results showed that PM extract at doses of 100 mg/kg, 200 mg/kg had increased the reproductive organs weight in immature rats and female ovariectomized rats. In addition, PM extract had increased the serum estradiol concentration and the vaginal cells growth by increasing the percentage of keratinocytes in female ovariectomized rats.Conclusions: Our results showed that PM extract has strong estrogenic activity in rats.

The Fine Structure of Rat Granulosa Cell Cultures Correlated with Progestin Secretion

1973 ◽  
Vol 31 ◽  
pp. 552-553
Author(s):  
T. M. Crisp ◽  
F.R. Denys
Keyword(s):  
Fine Structure ◽  
Granulosa Cell ◽  
Cell Cultures ◽  
Single Injection ◽  
Surrounding Medium ◽  
Petri Dish ◽  
Female Rats ◽  
Vaginal Smear ◽  
Immature Female ◽  
Serum Gonadotropin

The purpose of this paper is to present observations on the fine structure of rat granulosa cell cultures grown in the presence of an adenohypophyseal explant and to correlate the morphology of these cells with progestin secretion. Twenty-six day old immature female rats were given a single injection of 5 IU pregnant mares serum gonadotropin (PMS) in order to obtain ovaries with large vesicular follicles. At 66 hrs. post-PMS administration (estrus indicated by vaginal smear cytology), the ovaries were removed and placed in a petri dish containing medium 199 and 100 U penicillin/streptomycin (P/S)/ml. Under a 20X magnification dissecting microscope, some 5-8 vesicular follicles/ovary were punctured and the granulosa cells were expressed into the surrounding medium. The cells were transferred to centrifuge tubes and spun down at 1000 rpm for 5 mins.

Ultrastructural aspects of gymnosperms reproductive organs tissues due to their functional condition

1978 ◽  
Vol 36 (2) ◽  
pp. 440-441
Author(s):  
G. M. Kozubov
Keyword(s):  
Metabolic Activity ◽  
Functional Condition ◽  
Reproductive Organs ◽  
Considerable Change ◽  
Complicated Structure ◽  
Tetrad Stage ◽  
Ubisch Bodies ◽  
Similar Organization ◽  
Female Reproductive Organs ◽  
High Metabolic Activity

The ultrastructure of reproductive organs of pine, spruce, larch and ginkgo was investigated. It was found that the male reproductive organs possess similar organization. The most considerable change in the ultrastructure of the microsporocytes occur in meiosis. Sporoderm is being laid at the late tetrad stage. The cells of the male gameto-phyte are distinguished according to the metabolic activity of the or- ganells. They are most weakly developed in the spermiogenic cell. Ta-petum of the gymnosperms is of the periplasmodic - secretorial type. The Ubisch bodies which possess similar structure in the types investigated but are specific in details in different species are produced in tapetum.Parietal and subepidermal layers are distinguished for their high metabolic activity and are capable of the autonomous photosynthesis. Female reproductive organs differ more greatly in their struture and have the most complicated structure in primitive groups. On the first stages of their formation the inner cells of nucellus are transformed into the nucellar tapetum in which the structures similar to the Ubisch bodies taking part in the formation of the sporoderm of female gametophyte have been found.

Pelvic Impairments

2018 ◽  
Vol 23 (4) ◽  
pp. 9-10
Author(s):  
James Talmage ◽  
Jay Blaisdell
Keyword(s):  
Pelvic Ring ◽  
Reproductive Organs ◽  
High Impact ◽  
Pelvic Fractures ◽  
Motor Dysfunction ◽  
Impact Event ◽  
Concomitant Injuries ◽  
Rating Process ◽  
Pass Through ◽  
A Minor

Abstract Pelvic fractures are relatively uncommon, and in workers’ compensation most pelvic fractures are the result of an acute, high-impact event such as a fall from a roof or an automobile collision. A person with osteoporosis may sustain a pelvic fracture from a lower-impact injury such as a minor fall. Further, major parts of the bladder, bowel, reproductive organs, nerves, and blood vessels pass through the pelvic ring, and traumatic pelvic fractures that result from a high-impact event often coincide with damaged organs, significant bleeding, and sensory and motor dysfunction. Following are the steps in the rating process: 1) assign the diagnosis and impairment class for the pelvis; 2) assign the functional history, physical examination, and clinical studies grade modifiers; and 3) apply the net adjustment formula. Because pelvic fractures are so uncommon, raters may be less familiar with the rating process for these types of injuries. The diagnosis-based methodology for rating pelvic fractures is consistent with the process used to rate other musculoskeletal impairments. Evaluators must base the rating on reliable data when the patient is at maximum medical impairment and must assess possible impairment from concomitant injuries.

PHYSIOLOGICAL EFFECTS OF THE PINEAL GLAND IN ANDROGEN-STERILIZED FEMALE RATS

1970 ◽  
Vol 63 (4) ◽  
pp. 667-678 ◽  
Author(s):  
Russel J. Reiter
Keyword(s):  
Pineal Gland ◽  
Reproductive Organs ◽  
Female Rats ◽  
Inhibitory Influence ◽  
Light Deprivation ◽  
Vaginal Smears ◽  
Adult Rats ◽  
Androgen Treatment ◽  
Postnatal Treatment ◽  
Cervical Ganglia

ABSTRACT The influence of early androgen treatment, light deprivation (by blinding), pinealectomy and superior cervical ganglionectomy on the reproductive system of female rats was tested. Early postnatal treatment of rats with testosterone propionate caused adult rats to exhibit the characteristic signs of androgen sterilization; these included polyfollicular ovaries, normal-sized uteri and persistent vaginal cornification. If early androgentreated rats also were blinded the ovaries were smaller in size and contained fewer follicles, the uteri were greatly reduced in size and the incidence of vaginal oestrus was decreased by approximately 50% If in addition to blinding, androgen-sterilized animals were subjected to either removal of the pineal gland or superior cervical ganglia, the reproductive organs and the vaginal smears were indistinguishable from those of testosterone-treated rats with eyes. These data indicate that the inhibitory influence of blinding on the pituitary-ovarian axis was mediated through the sympathetic nervous system and the pineal gland. The restraining influence of light deprivation on the growth of the reproductive organs was not permanent as illustrated by the fact that if these animals were kept to 120 days of age the ovaries and uteri grew to the same level as those of pinealectomized control rats.

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