scholarly journals Metabolism of the developing retina. 2. The effect of an inherited retinal degeneration on the development of glycolysis in the rat retina*

1959 ◽  
Vol 72 (3) ◽  
pp. 459-461 ◽  
Author(s):  
C. N. Graymore ◽  
Katharine Tansley ◽  
Margaret Kerly
Keyword(s):  
Retinal Degeneration ◽  
Rat Retina ◽  
Inherited Retinal Degeneration

Assessment of inner retinal oxygen metrics and thickness in a mouse model of inherited retinal degeneration

2021 ◽  
Vol 205 ◽  
pp. 108480
Author(s):  
Mansour Rahimi ◽  
Sophie Leahy ◽  
Nathanael Matei ◽  
Norman P. Blair ◽  
Shinwu Jeong ◽  
...  
Keyword(s):  
Mouse Model ◽  
Retinal Degeneration ◽  
Inherited Retinal Degeneration

Neurochemical studies on the inherited retinal degeneration of the rat

1963 ◽  
Vol 3 (7-8) ◽  
pp. 271-280 ◽  
Author(s):  
Vincenzo Bonavita ◽  
Francesco Ponte ◽  
Giuseppe Amore
Keyword(s):  
Retinal Degeneration ◽  
Inherited Retinal Degeneration

scholarly journals CRISPR-Cas9 genome engineering: Treating inherited retinal degeneration

2018 ◽  
Vol 65 ◽  
pp. 28-49 ◽  
Author(s):  
Erin R. Burnight ◽  
Joseph C. Giacalone ◽  
Jessica A. Cooke ◽  
Jessica R. Thompson ◽  
Laura R. Bohrer ◽  
...  
Keyword(s):  
Retinal Degeneration ◽  
Genome Engineering ◽  
Inherited Retinal Degeneration

scholarly journals Increased proteasomal activity supports photoreceptor survival in inherited retinal degeneration

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Ekaterina S. Lobanova ◽  
Stella Finkelstein ◽  
Jing Li ◽  
Amanda M. Travis ◽  
Ying Hao ◽  
...  
Keyword(s):  
Retinal Degeneration ◽  
Proteasomal Activity ◽  
Inherited Retinal Degeneration

Inherited retinal degeneration current genetics practices – a needs assessment

2020 ◽  
Vol 41 (6) ◽  
pp. 533-538
Author(s):  
Sydney Strait ◽  
Rebecca Loman ◽  
Lindsay Erickson ◽  
Meghan DeBenedictis
Keyword(s):  
Needs Assessment ◽  
Retinal Degeneration ◽  
Inherited Retinal Degeneration

scholarly journals Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss

Cells ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 931 ◽  
Author(s):  
Gayle B. Collin ◽  
Navdeep Gogna ◽  
Bo Chang ◽  
Nattaya Damkham ◽  
Jai Pinkney ◽  
...  
Keyword(s):  
Retinal Degeneration ◽  
Mouse Models ◽  
Laboratory Mouse ◽  
Gene List ◽  
Cell Loss ◽  
Mouse Genome Informatics ◽  
Future Research ◽  
Damage Repair ◽  
Wide Range ◽  
Inherited Retinal Degeneration

Inherited retinal degeneration (RD) leads to the impairment or loss of vision in millions of individuals worldwide, most frequently due to the loss of photoreceptor (PR) cells. Animal models, particularly the laboratory mouse, have been used to understand the pathogenic mechanisms that underlie PR cell loss and to explore therapies that may prevent, delay, or reverse RD. Here, we reviewed entries in the Mouse Genome Informatics and PubMed databases to compile a comprehensive list of monogenic mouse models in which PR cell loss is demonstrated. The progression of PR cell loss with postnatal age was documented in mutant alleles of genes grouped by biological function. As anticipated, a wide range in the onset and rate of cell loss was observed among the reported models. The analysis underscored relationships between RD genes and ciliary function, transcription-coupled DNA damage repair, and cellular chloride homeostasis. Comparing the mouse gene list to human RD genes identified in the RetNet database revealed that mouse models are available for 40% of the known human diseases, suggesting opportunities for future research. This work may provide insight into the molecular players and pathways through which PR degenerative disease occurs and may be useful for planning translational studies.

Photoreceptor Cell Death Mechanisms in Inherited Retinal Degeneration

2008 ◽  
Vol 38 (3) ◽  
pp. 253-269 ◽  
Author(s):  
Javier Sancho-Pelluz ◽  
Blanca Arango-Gonzalez ◽  
Stefan Kustermann ◽  
Francisco Javier Romero ◽  
Theo van Veen ◽  
...  
Keyword(s):  
Cell Death ◽  
Retinal Degeneration ◽  
Photoreceptor Cell ◽  
Cell Death Mechanisms ◽  
Inherited Retinal Degeneration
Sign in / Sign up

Export Citation Format

Share Document