scholarly journals Further developments of rapid volumetric methods for the determination of amino-acids, organic acids and bases

1928 ◽  
Vol 22 (1) ◽  
pp. 208-221 ◽  
Author(s):  
Frederick William Foreman
Keyword(s):  
Amino Acids ◽  
Organic Acids ◽  
Acids And Bases ◽  
Volumetric Methods

scholarly journals General Analytical Procedure for Determination of Acidity Parameters of Weak Acids and Bases

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Bogusław Pilarski ◽  
Roman Kaliszan ◽  
Dariusz Wyrzykowski ◽  
Janusz Młodzianowski ◽  
Agata Balińska
Keyword(s):  
Organic Acids ◽  
Excellent Agreement ◽  
Analytical Procedure ◽  
Water Solution ◽  
Weak Acids ◽  
Weak Organic Acids ◽  
General Methodology ◽  
Acids And Bases

The paper presents a new convenient, inexpensive, and reagent-saving general methodology for the determination ofpKavalues for components of the mixture of diverse chemical classes weak organic acids and bases in water solution, without the need to separate individual analytes. The data obtained from simple pH-metric microtitrations are numerically processed into reliablepKavalues for each component of the mixture. Excellent agreement has been obtained between the determinedpKavalues and the reference literature data for compounds studied.

scholarly journals Determination of liposome/water partition coefficients of organic acids and bases by solid-phase microextraction

The Analyst ◽  
2001 ◽  
Vol 127 (1) ◽  
pp. 42-48 ◽  
Author(s):  
Beate I. Escher ◽  
Michael Berg ◽  
Jürg Mühlemann ◽  
Martin A. A. Schwarz ◽  
Joop L. M. Hermens ◽  
...  
Keyword(s):  
Organic Acids ◽  
Partition Coefficients ◽  
Solid Phase Microextraction ◽  
Solid Phase ◽  
Acids And Bases

scholarly journals Determination of free amino acids, organic acids, and nucleotides in 29 elegant spices

2020 ◽  
Vol 8 (7) ◽  
pp. 3777-3792 ◽  
Author(s):  
Wen Duan ◽  
Yan Huang ◽  
Junfei Xiao ◽  
Yuyu Zhang ◽  
Yizhuang Tang
Keyword(s):  
Amino Acids ◽  
Organic Acids ◽  
Free Amino Acids ◽  
Free Amino

scholarly journals Determination of the reference values of amino acids and acylcarnitines level in the newborn dry blood spots in Ukraine

2018 ◽  
Vol 16 (1) ◽  
pp. 12-19
Author(s):  
O. I. Barvinska ◽  
N. V. Olkhovych ◽  
N. G. Gorovenko
Keyword(s):  
Amino Acids ◽  
Organic Acids ◽  
Geographical Origin ◽  
Reference Intervals ◽  
Inherited Disorders ◽  
Main Method ◽  
Blood Spots ◽  
Liquid Chromatography Tandem Mass ◽  
Term Newborns

Aim. Implementation of neonatal screening of the group of severe inherited disorders of amino acids, fatty and organic acids metabolism in Ukraine involves determination of the biological variation of amino acids and acylcarnitines level in the blood that depends on the gender, geographical origin of the samples and the gestation term of newborn. Methods. The main method of rapid and reliable diagnosis of this group of inherited disorders is determination of amino acids and acylcarnitines level by liquid chromatography tandem mass spectrometry. Results. Reference intervals of amino acids and acylcarnitines concentration in dry blood samples of newborns from different regions of Ukraine haven’t differed. However, it was found necessity to use separate reference intervals of some amino acids and acylcarnitines (citrulline, arginine, methionine, leucine, tyrosine, alanine, histidine, C0, C3, C3DC, C4, C5, C6, C8, C8:1, C10:2, C12, C14:1, C16, C18OH, C18:1OH) for premature and full-term newborns. Also, it was revealed that for male and female newborns it is necessary to use different reference intervals of citrulline, leucine, C8:1, arginine, methionine, C5, C8. Conclusions. In this study it was found that variation of amino acids and acylcarnitines concentration in dry blood spots depends on the newborns gestation term and sex. We have proposed a two-stage procedure of biomarkers interpretation for which the values variation in different neonatal groups was detected. Keywords: amino acids and acylcarnitines reference intervals, inherited disorders of amino acids, fatty and organic acids metabolism, newborn screening.

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