scholarly journals A Study of the Relation of the Quantity of Fat-soluble Organic Factor in the Diet to the Degree of Calcification of the Bones and the Development of Experimental Rickets in Rats

1923 ◽  
Vol 17 (2) ◽  
pp. 298-326 ◽  
Author(s):  
Harry Goldblatt
Keyword(s):  
Organic Factor

scholarly journals Studies on unidentified growth factors

1974 ◽  
Vol 31 (2) ◽  
pp. 179-184 ◽  
Author(s):  
J. Bunyan ◽  
Elspeth A. Murrell ◽  
M. A. Cawthorne ◽  
B. T. Redman
Keyword(s):  
Amino Acids ◽  
Growth Rate ◽  
Amino Acid ◽  
Soya Bean ◽  
Torula Yeast ◽  
Acid Diet ◽  
Organic Growth ◽  
Organic Factor ◽  
Amino Acid Diet ◽  
Low Activity

1. Chicks at 10 d of age were given diets containing all the nutrients known to be required, with L-amino acids in place of protein. Dietary supplements were added isonitrogenously.2. Ox liver (100 g/kg) greatly improved the chicks' growth rate, whereas torula yeast (50 g/kg) was inactive. The activity of fresh moist liver was considered to be due largely to an organic factor, because of the inactivity of water and the low activity of liver ash.3. The growth rates of chicks receiving diets based upon casein and isolated soya-bean protein were significantly improved by the inclusion of 100 g fresh ox liver/kg, but not of 50 g torula yeast/kg.4. These results show that chicks receiving an amino acid diet require an organic growth factor (Progressin) that differs from the yeast factor required by rats receiving an amino acid diet.

Organic Mania Induced by Phenytoin: A Case Report*

1989 ◽  
Vol 34 (8) ◽  
pp. 827-828 ◽  
Author(s):  
S.B. Patten ◽  
G.M. Klein ◽  
C. Lussier ◽  
R. Sawa
Keyword(s):  
Multiple Sclerosis ◽  
Case Report ◽  
Temporal Lobe Epilepsy ◽  
Mood Disorder ◽  
Mental State ◽  
Clinical Picture ◽  
Manic Episode ◽  
Baclofen Withdrawal ◽  
Organic Factor ◽  
State Score

Organic Mood Disorder of the manic type is a syndrome which resembles a manic episode but is due to a specific organic factor. Organic mania may be associated with a variety of physical illnesses such as temporal lobe epilepsy, multiple sclerosis, neoplasms and hyperthyroidism. In addition, organic mania can be associated with drugs including L-dopa, decongestants, sympathomimetics, steroids, baclofen withdrawal, cimetidine, and possibly captopril. This report describes a case of a 74 year old female who presented with a full syndrome of mania soon after being started on Phenytoin. Neither the clinical picture, Mini-mental state score, nor EEG findings were suggestive of delirium. The syndrome resolved soon after the phenytoin was discontinued. This case suggests that phenytoin should be added to the list of medications capable of producing Organic Mood Syndrome, manic type.

Symptom Complexes in Childhood Psychosis

1967 ◽  
Vol 1 (1) ◽  
pp. 30-34
Author(s):  
Stanley Gold ◽  
I. L. Neufeld
Keyword(s):  
Factor Analysis ◽  
The Body ◽  
Sensory Stimuli ◽  
Homogeneous Groups ◽  
Childhood Psychosis ◽  
Organic Factor

In an attempt to differentiate clinically between sub-groups of children diagnosed psychotic, fifty-six children were assessed on a graphic testing scale using twenty items. Results subjected to factor analysis indicated two significant sub-classes. Factor 1: Characterised by bizarre posturing; abnormal motility patterns; aloofness; impersonal use of people; and self directed aggression. This was designated a “schizophrenic” factor. Factor 2: Characterished by excessive response to sensory stimuli; scrutiny of the body; hyperkinesis and externally directed aggression. This was designated a “non schizophrenic” (? organic) factor. Although clinically overlapping, it is thought that application of the above criteria may provide more homogeneous groups, with implications for research, therapy and prognosis.

scholarly journals EEG in psychiatric practice: to do or not to do?

2011 ◽  
Vol 17 (2) ◽  
pp. 114-121 ◽  
Author(s):  
Vellingiri Raja Badrakalimuthu ◽  
Radhika Swamiraju ◽  
Hugo de Waal
Keyword(s):  
Clinical Assessment ◽  
Crucial Role ◽  
Detection Rate ◽  
Brain Activity ◽  
Low Cost ◽  
Abnormality Detection ◽  
Spontaneous Brain Activity ◽  
Non Invasive ◽  
Organic Factor ◽  
Eeg Changes

SummaryElectroencephalography (EEG) is a non-invasive investigation that can aid the diagnosis of psychiatric and neuropsychiatric disorders. A good predictor of an abnormal EEG recording is the presence of an organic factor identified during the clinical assessment. The non-invasiveness and low cost of the procedure and its ability to measure spontaneous brain activity appear to attract clinicians to utilise this investigative tool. However, studies have reported that EEGs arising from psychiatric referrals have the lowest abnormality detection rate. The focus of this article is to improve this by highlighting the current pitfalls and providing recommendations for appropriate utilisation of EEG. We describe specific EEG changes associated with major psychiatric disorders. We conclude by offering pragmatic considerations when referring a patient for EEG, emphasising the fact that the information provided to the neurophysiologist plays a crucial role in interpreting the EEG recording in a diagnostically meaningful way.

scholarly journals The Supplementary Value of Light Rays to a Diet Graded in its Content of Fat-Soluble Organic Factor

1923 ◽  
Vol 17 (4-5) ◽  
pp. 622-629 ◽  
Author(s):  
Harry Goldblatt ◽  
Katharine Marjorie Soames
Keyword(s):  
Light Rays ◽  
Organic Factor

A case of persecutory delusions presenting in a woman with normal pressure hydrocephalus due to idiopathic aqueductal stenosis

2011 ◽  
Vol 26 (S2) ◽  
pp. 1360-1360
Author(s):  
S. Chatziioannidis ◽  
N. Nikolaidis ◽  
I. Charatsidou ◽  
E. Ramantani ◽  
I. Genaris ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Normal Pressure Hydrocephalus ◽  
Psychiatric Symptoms ◽  
Normal Pressure ◽  
Aqueductal Stenosis ◽  
Behavioral Disorder ◽  
Psychotic Symptoms ◽  
Persecutory Delusions ◽  
Abnormal Accumulation ◽  
Organic Factor

IntroductionNormal pressure hydrocephalus due to idiopathic aqueductal stenosis is an abnormal accumulation of CSF in the cerebral ventricles caused by an obstruction in the Sylvian aqueduct. Although NPH typically presents with the progressive ‘triad’ of cognitive impairment, gait disturbance and urinary incontinence it has been described that it rarely manifests with predominant psychotic symptoms.Objective and methodA clinical case was followed and reviewed to illustrate the psychiatric symptoms in NPH.ResultsA 32-year-old female was admitted to our acute psychiatric department because she exhibited verbal and physical aggressive behavior while being in an agitated state with persecutory delusions. Symptoms appeared and gradually exacerbated over a 5-year period reaching their climax two weeks before admission. The patient's increased body weight and bradykinetic appearance implied the presence of an underlying organic factor. However her endocrinological workup proved normal and her neurological examination revealed no actual focal deficits. An EEG also proved negative for seizure activity and encephalopathy.Neuropsychological batteries showed mild cognitive impairment and a CT scan revealed considerable dilatation of the ventricular system due to idiopathic aqueductal stenosis. While a conservative approach was chosen for the treatment of NPH our patient was initiated on atypical antipsychotics showing marked improvement of her psychiatric symptomatology.ConclusionsPatients without a prior psychiatric history who have soft nonlocalising neurological signs and mild cognitive deficits in association with prominent psychotic symptomatology should raise our index of suspicion and prompt the clinician to explore the existence of an organic factor contributing to a behavioral disorder.

Evidence that calcium-dependent cellular processes are involved in the stiffening response of holothurian dermis and that dermal cells contain an organic stiffening factor

1995 ◽  
Vol 198 (9) ◽  
pp. 1951-1961 ◽  
Author(s):  
J Trotter ◽  
T Koob
Keyword(s):  
Extracellular Matrix ◽  
Alternative Hypothesis ◽  
Cellular Regulation ◽  
Calcium Dependent ◽  
Cellular Processes ◽  
Cellular Events ◽  
Organic Factor ◽  
Cellular Pathways ◽  
Dermal Cells ◽  
Stiffening Factor

Although previous investigations have shown that experimental increases and decreases of the concentration of extracellular Ca2+ produce correlated changes in the stiffness of holothurian dermis, they have failed to determine whether the Ca2+-correlated changes were due to Ca2+-dependent cellular events or to direct effects of Ca2+ on the viscosity of the extracellular matrix. We have addressed this question by testing two explicit predictions of the latter hypothesis: that dermal stiffness should be correlated with the Ca2+ concentration in the absence of viable cells; and that, in the presence of a normal extracellular Ca2+ concentration, drugs that inhibit cellular pathways dependent on Ca2+ should not affect dermal stiffness. Our results are inconsistent with the hypothesis and support the alternative hypothesis that Ca2+ is important only in the cellular regulation of dermal stiffness. In addition, we have extracted from dermal cells an organic factor that stiffens the extracellular matrix.

scholarly journals EXPERIMENTAL RICKETS IN RABBITS

1925 ◽  
Vol 42 (4) ◽  
pp. 499-506 ◽  
Author(s):  
Harry Goldblatt ◽  
Alan R. Moritz
Keyword(s):  
Calcium Content ◽  
Cod Liver Oil ◽  
High Calcium ◽  
Organic Factor

Rickets has been produced experimentally in rabbits by the administration of diets deficient in the antirachitic organic factor and phosphorus but with a high calcium content. Cod liver oil added to these rickets-producing diets prevented the development of rickets in rabbits.

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