scholarly journals Isothermal titration calorimetry: feeling the heat

2019 ◽  
Vol 41 (2) ◽  
pp. 4-7
Author(s):  
Gemma Harris ◽  
David J. Scott
Keyword(s):  
Small Molecules ◽  
Isothermal Titration Calorimetry ◽  
Titration Calorimetry ◽  
Good Data ◽  
Background Theory ◽  
Complex Phenomena ◽  
Underlying Processes

Isothermal titration calorimetry (ITC) has become one of the mainstays of determining the affinity of small molecules with macromolecules. As such there has been a resurgence in interest in the underlying processes that contribute to a ‘good’ ITC experiment. In this article we discuss the thermodynamic origins of the data seen in an ITC experiment, some of the background theory and exemplars of what good data look like. We also discuss the origins of more complex phenomena seen with ITC, and how these may be interpreted.

scholarly journals Plasmon-Mediated Oxidation Reaction on Au/p-Cu2O: The Origin of Hot Holes

Physchem ◽  
2021 ◽  
Vol 1 (2) ◽  
pp. 163-175
Author(s):  
Philipp Hawe ◽  
Vitor R. R. Silveira ◽  
Robert Bericat Vadell ◽  
Erik Lewin ◽  
Jacinto Sá
Keyword(s):  
Optical Absorption ◽  
Small Molecules ◽  
Photocatalytic Efficiency ◽  
Sustainable Solutions ◽  
Hot Carrier ◽  
Mitigate Climate Change ◽  
Underlying Processes ◽  
Direct Use ◽  
Mediated Oxidation ◽  
High Optical Absorption

More sustainable solutions are needed to produce chemicals and fuels, mainly to face rising demands and mitigate climate change. Light, as a reagent, has emerged as a route to activate small molecules, e.g., H2O, CO2, N2, and make complex chemicals in a process called photocatalysis. Several photosystems have been proposed, with plasmonic technology emerging as one the most promising technologies due to its high optical absorption and hot-carrier formation. However, the lifetime of hot carriers is unsuitable for direct use; therefore, they are normally coupled with suitable charge-accepting materials, such as semiconductors. Herein, a system is reported consisting of Au supported in p-Cu2O. The combination of p-Cu2O intrinsic photoactivity with the plasmonic properties of Au extended the system’s optical absorption range, increasing photocatalytic efficiency. More importantly, the system enabled us to study the underlying processes responsible for hot-hole transfer to p-Cu2O. Based on photocatalytic studies, it was concluded that most of the holes involved in aniline photo-oxidation come from hot-carrier injections, not from the PIRET process.

scholarly journals Thermodynamic characterization of calcium-milk protein interaction by isothermal titration calorimetry

2009 ◽  
Vol 89 (3-4) ◽  
pp. 257-267 ◽  
Author(s):  
Latha-Selvi Canabady-Rochelle ◽  
Christian Sanchez ◽  
Michel Mellema ◽  
Sylvie Banon
Keyword(s):  
Isothermal Titration Calorimetry ◽  
Protein Interaction ◽  
Milk Protein ◽  
Titration Calorimetry ◽  
Thermodynamic Characterization
Sign in / Sign up

Export Citation Format

Share Document