Spontaneous free radical/spin adduct formation and 1,3-dipolar molecular addition in reactions of cyanohalocarbons and C-phenyl N-tert-butyl nitrone (PBN)

1996 ◽  
pp. 1183 ◽  
Author(s):  
Hong Sang ◽  
Edward G. Janzen ◽  
J. Lee Poyer
Keyword(s):  
Free Radical ◽  
Adduct Formation ◽  
Spin Adduct ◽  
Tert Butyl

On the spin trapping of chlorine atoms. Competition from chloride ions

1991 ◽  
Vol 69 (7) ◽  
pp. 1131-1133 ◽  
Author(s):  
Detlef Rehorek ◽  
Edward G. Janzen ◽  
Yashige Kotake
Keyword(s):  
Key Words ◽  
Epr Spectroscopy ◽  
Spin Trapping ◽  
Adduct Formation ◽  
Chloride Ions ◽  
Spin Adduct ◽  
Phenyl Radicals ◽  
Chlorine Atoms ◽  
Tert Butyl ◽  
Epr Spin Trapping

Chlorine atoms generated by photolysis of hexachloroethane add to C-phenyl-N-tert-butyl nitrone (PBN) to form persistent spin adducts that are readily detectable by EPR spectroscopy. The presence of chloride ions reduces spin adduct formation competitively. Chlorine atoms also react with tetraphenylarsenium ions to liberate phenyl radicals by radical replacement. Key words: EPR, spin trapping, C-phenyl-N-tert-butyl nitrone, PBN, photolysis, chlorine atoms, tetraphenylarsenium ion, hexachloroethane.

Catalytic etherification of glycerol to tert-butyl glycerol ethers using tert-butanol over sulfonic acid functionalized mesoporous polymer

RSC Advances ◽  
2016 ◽  
Vol 6 (86) ◽  
pp. 82654-82660 ◽  
Author(s):  
Pandian Manjunathan ◽  
Manish Kumar ◽  
Sathyapal R. Churipard ◽  
S. Sivasankaran ◽  
Ganapati V. Shanbhag ◽  
...  
Keyword(s):  
Free Radical ◽  
Radical Polymerization ◽  
Sulfonic Acid ◽  
Solvothermal Method ◽  
Free Radical Polymerization ◽  
Tert Butyl ◽  
Mesoporous Polymer ◽  
Glycerol Ethers ◽  
Tert Butanol

Mesoporous polymers (MP) were synthesized by free radical polymerization of divinylbenzene by a solvothermal method followed by sulfonic acid functionalization by a post synthetic modification with conc.

Paraquat-induced lung injury: prevention by N-tert-butyl-alpha-phenylnitrone, a free-radical spin-trapping agent

1992 ◽  
Vol 262 (2) ◽  
pp. L147-L152
Author(s):  
T. Sata ◽  
E. Kubota ◽  
H. P. Misra ◽  
M. Mojarad ◽  
H. Pakbaz ◽  
...  
Keyword(s):  
Free Radical ◽  
Lung Injury ◽  
Guinea Pig ◽  
Weight Ratio ◽  
Spin Trapping ◽  
Lung Weight ◽  
Paramagnetic Resonance ◽  
Arterial Perfusion ◽  
Tert Butyl ◽  
Trapping Agent

The herbicide paraquat causes lung injury that is believed to be oxygen-radical mediated. To further characterize this injury and explore new methods of preventing it, we used the spin-trapping agent N-tert-butyl-alpha-phenylnitrone (PBN) to identify the paraquat radical in lung tissue and to reduce the injury resulting from the subsequent generation of reactive oxygen species. The formation of a paraquat free radical by guinea pig lung was detected under anaerobic conditions by electron paramagnetic resonance spectrometry. Infused (25, 50, or 100 mg/kg) into guinea pig lungs (perfused at constant flow with Krebs solution containing 4% bovine serum albumin and ventilated with 95% O2-5% CO2), paraquat produced dose-dependent increases in peak airway pressure (Paw), mean pulmonary arterial perfusion pressure (Ppa), and wet-to-dry (W/D) lung weight ratio. At 100 mg/kg, paraquat increased Paw by 589.6 +/- 59.8% (mean +/- SE, n = 8) and W/D ratio from 5.33 +/- 0.07 to 6.29 +/- 0.11 (P less than 0.001). Pulmonary vascular leak index increased from 0.40 +/- 0.09 to 1.96 +/- 0.45 (P less than 0.02), without changes in pulmonary microvascular pressure. Perfusate concentrations of thromboxane B2 and 6-ketoprostaglandin F1 alpha increased, but indomethacin did not reduce the injury. PBN (2.3 mM) markedly attenuated all evidence of lung injury, which was also reduced by catalase, mannitol, ethanol, and vitamin E.(ABSTRACT TRUNCATED AT 250 WORDS)

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