Studies on the biosynthesis of the mycotoxin austin, a meroterpenoid metabolite of Aspergillus ustus

1989 ◽  
pp. 807 ◽  
Author(s):  
Salman A. Ahmed ◽  
Fiona E. Scott ◽  
Desmond J. Stenzel ◽  
Thomas J. Simpson ◽  
Richard N. Moore ◽  
...  
Keyword(s):  
Aspergillus Ustus

scholarly journals Micromycetes-resistant colored cotton is promising material to reduce mycotoxins amounts in textiles

2020 ◽  
Vol 164 ◽  
pp. 06015
Author(s):  
Kseniia Illarionova ◽  
Sergey Grigoryev
Keyword(s):  
Upland Cotton ◽  
Federal District ◽  
Cotton Fibers ◽  
Rhizopus Nigricans ◽  
Aspergillus Ustus ◽  
Cotton Plants ◽  
Colored Cotton ◽  
Penicillium Aurantiogriseum ◽  
The Mean ◽  
White Cotton

The aim of research was to characterize epiphyte micromycetes observed on variable cotton fibers accessions, to estimate the range of fiber destruction and select cotton, which were the most resistant to fungus damage. The accessions of differently colored Upland Cotton varieties (Gossypium hirsutum L.) evaluated: eleven cotton of natural green, twelve – of brown and eleven of conventional white color. Cotton plants have been grown in Sothern Federal District, RF. The fiber samples for the study were placed into a thermostat in sterile Petri dishes on moistened filter paper in order to stimulate the development of mycelium or sporulation of fungi naturally occurred on fibers. Incubation carried out in a thermostat at a +24-28 °C, humidity of 90-100% and exposed for 28 days. The samples examined with a microscope or binocular magnifier. Aspergillus ustus (Bainier), A. fumigatus Fresen., A. niger v. Tiegh., A. flavus Link, Penicillium aurantiogriseum Dierckx, P. notatum Westling, Rhizopus nigricans Ehrenb. and Alternaria alternata (Fuier) Keissler were detected. Compared with exposed white, accession of green and brown colors were significantly resistant to fungus. The mean of destruction (K) of white cotton varied up to 0.95, but colored accessions not exceeded 0.3 (initial destruction of the surface, not affecting internal fiber’s structure).

METABOLIC PRODUCTS OF ASPERGILLUS USTUS

1946 ◽  
Vol 68 (4) ◽  
pp. 725-726 ◽  
Author(s):  
W. E. Doering ◽  
R. J. Dubos ◽  
D. S. Noyce ◽  
R. Dreyfus
Keyword(s):  
Aspergillus Ustus ◽  
Metabolic Products

ChemInform Abstract: Novel Drimane Sesquiterpene Esters from Aspergillus ustus var. pseudodeflectus with Endothelin Receptor Binding Activity.

ChemInform ◽  
2010 ◽  
Vol 27 (47) ◽  
pp. no-no
Author(s):  
M. A. HAYES ◽  
S. K. WRIGLEY ◽  
I. CHETLAND ◽  
E. E. REYNOLDS ◽  
A. M. AINSWORTH ◽  
...  
Keyword(s):  
Receptor Binding ◽  
Binding Activity ◽  
Endothelin Receptor ◽  
Aspergillus Ustus ◽  
Receptor Binding Activity

Aspergillus ustus. [Descriptions of Fungi and Bacteria].

2000 ◽  
Author(s):  
Z. Kozakiewicz
Keyword(s):  
Liver Transplant ◽  
Invasive Aspergillosis ◽  
Polyurethane Foam ◽  
Geographical Distribution ◽  
World Wide ◽  
Soil Types ◽  
Cutaneous Infection ◽  
Aspergillus Ustus ◽  
Radio Equipment ◽  
Disseminated Aspergillosis

Abstract A description is provided for Aspergillus ustus. Information is included on the disease caused by the organism, its transmission, geographical distribution, and hosts. HOSTS: Found in all soil types (DOMSCH et al., 1980), but also isolated from radio equipment, polyurethane foam, flannel bag, sugar and fermented cocoa (CABI BIOSCIENCE, 1999). DISEASE: On man it has been implicated in a case of primary cutaneous infection following a liver transplant (STILLER et al., 1994), isolated from invasive aspergillosis (VERWEU et al., 1999) and disseminated aspergillosis (IWEN et al., 1998). GEOGRAPHICAL DISTRIBUTION: World-wide, but with preference for tropical and subtropical regions.

(±)-Usphenethylones A−C, three pairs of heterodimeric polyketide enantiomers from Aspergillus ustus 3.3904

2022 ◽  
Author(s):  
Hanli Ruan ◽  
Xiaogang Peng ◽  
Shuang Zhou ◽  
Junjun Liu ◽  
Ying Gao ◽  
...  
Keyword(s):  
Aspergillus Ustus ◽  
Culture Extract

Three pairs of novel heterodimeric polyketide enantiomers, (±)-usphenethylones A−C (1−3), were isolated from the culture extract of Aspergillus ustus 3.3904. Compounds 1−3 represent two unique heterodimerization patterns of a phenethyl...

scholarly journals Oxepinamide F biosynthesis involves enzymatic d-aminoacyl epimerization, 3H-oxepin formation, and hydroxylation induced double bond migration

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Liujuan Zheng ◽  
Haowen Wang ◽  
Aili Fan ◽  
Shu-Ming Li
Keyword(s):  
Cytochrome P450 ◽  
Double Bond ◽  
Biosynthetic Pathway ◽  
Hydroxyl Group ◽  
Cytochrome P450 Enzyme ◽  
Double Bond Migration ◽  
Feeding Experiments ◽  
Aspergillus Ustus ◽  
P450 Enzyme ◽  
Derivatives Of

Abstract Oxepinamides are derivatives of anthranilyl-containing tripeptides and share an oxepin ring and a fused pyrimidinone moiety. To the best of our knowledge, no studies have been reported on the elucidation of an oxepinamide biosynthetic pathway and conversion of a quinazolinone to a pyrimidinone-fused 1H-oxepin framework by a cytochrome P450 enzyme in fungal natural product biosynthesis. Here we report the isolation of oxepinamide F from Aspergillus ustus and identification of its biosynthetic pathway by gene deletion, heterologous expression, feeding experiments, and enzyme assays. The nonribosomal peptide synthase (NRPS) OpaA assembles the quinazolinone core with d-Phe incorporation. The cytochrome P450 enzyme OpaB catalyzes alone the oxepin ring formation. The flavoenzyme OpaC installs subsequently one hydroxyl group at the oxepin ring, accompanied by double bond migration. The epimerase OpaE changes the d-Phe residue back to l-form, which is essential for the final methylation by OpaF.

Synthesis of the New Furo[3,2-h]isoquinoline Alkaloid, TMC-120B from Aspergillus ustus.

ChemInform ◽  
2005 ◽  
Vol 36 (38) ◽  
Author(s):  
Teppei Kumemura ◽  
Tominari Choshi ◽  
Aki Hirata ◽  
Mitsuko Sera ◽  
Yohhei Takahashi ◽  
...  
Keyword(s):  
Isoquinoline Alkaloid ◽  
Aspergillus Ustus

Disseminated Aspergillus ustus Infection Following Cardiac Surgery

1983 ◽  
Vol 80 (3) ◽  
pp. 408-411 ◽  
Author(s):  
Lawrence M. Weiss ◽  
William A. Thiemke
Keyword(s):  
Cardiac Surgery ◽  
Aspergillus Ustus

scholarly journals Aspergillus calidoustus sp. nov., Causative Agent of Human Infections Previously Assigned to Aspergillus ustus

2008 ◽  
Vol 7 (4) ◽  
pp. 630-638 ◽  
Author(s):  
János Varga ◽  
Jos Houbraken ◽  
Henrich A. L. Van Der Lee ◽  
Paul E. Verweij ◽  
Robert A. Samson
Keyword(s):  
Antifungal Susceptibility ◽  
Antifungal Drugs ◽  
Protein Coding ◽  
Coding Regions ◽  
Aspergillus Ustus ◽  
Invasive Infections ◽  
Human Infections ◽  
Immunocompromised Hosts ◽  
A New Species

ABSTRACT Aspergillus ustus is a relatively rare human pathogen causing invasive infections in immunocompromised hosts. In this study isolates originating from clinical and other sources have been examined using molecular, morphological, and physiological approaches to clarify their species assignment. Phylogenetic analysis of partial β-tubulin, calmodulin, actin, and intergenic transcribed spacer sequences indicated that none of the clinical isolates recognized previously as A. ustus belongs to this species. All but two of these isolates formed a well-defined clade related to A. pseudodeflectus based on sequence analysis of protein-coding regions. Morphological and physiological examination of these isolates indicated that they are able to grow above 37°C, in contrast with A. ustus isolates, and give a positive Ehrlich reaction, in contrast with related species including A. granulosus, A. ustus, and A. pseudodeflectus. These isolates are proposed as a new species, A. calidoustus. Antifungal susceptibility testing showed that this species has decreased susceptibilities to several antifungal drugs. The triazoles are inactive in vitro, including the new azole posaconazole.

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